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Items: 14

1.

Discovery of Small Molecules for the Reversal of T Cell Exhaustion.

Marro BS, Zak J, Zavareh RB, Teijaro JR, Lairson LL, Oldstone MBA.

Cell Rep. 2019 Dec 3;29(10):3293-3302.e3. doi: 10.1016/j.celrep.2019.10.119.

2.

IL-27 promotes the expansion of self-renewing CD8+ T cells in persistent viral infection.

Huang Z, Zak J, Pratumchai I, Shaabani N, Vartabedian VF, Nguyen N, Wu T, Xiao C, Teijaro JR.

J Exp Med. 2019 Aug 5;216(8):1791-1808. doi: 10.1084/jem.20190173. Epub 2019 Jun 4.

3.

Heterozygous Variants in KMT2E Cause a Spectrum of Neurodevelopmental Disorders and Epilepsy.

O'Donnell-Luria AH, Pais LS, Faundes V, Wood JC, Sveden A, Luria V, Abou Jamra R, Accogli A, Amburgey K, Anderlid BM, Azzarello-Burri S, Basinger AA, Bianchini C, Bird LM, Buchert R, Carre W, Ceulemans S, Charles P, Cox H, Culliton L, Currò A; Deciphering Developmental Disorders (DDD) Study, Demurger F, Dowling JJ, Duban-Bedu B, Dubourg C, Eiset SE, Escobar LF, Ferrarini A, Haack TB, Hashim M, Heide S, Helbig KL, Helbig I, Heredia R, Héron D, Isidor B, Jonasson AR, Joset P, Keren B, Kok F, Kroes HY, Lavillaureix A, Lu X, Maas SM, Maegawa GHB, Marcelis CLM, Mark PR, Masruha MR, McLaughlin HM, McWalter K, Melchinger EU, Mercimek-Andrews S, Nava C, Pendziwiat M, Person R, Ramelli GP, Ramos LLP, Rauch A, Reavey C, Renieri A, Rieß A, Sanchez-Valle A, Sattar S, Saunders C, Schwarz N, Smol T, Srour M, Steindl K, Syrbe S, Taylor JC, Telegrafi A, Thiffault I, Trauner DA, van der Linden H Jr, van Koningsbruggen S, Villard L, Vogel I, Vogt J, Weber YG, Wentzensen IM, Widjaja E, Zak J, Baxter S, Banka S, Rodan LH.

Am J Hum Genet. 2019 Jun 6;104(6):1210-1222. doi: 10.1016/j.ajhg.2019.03.021. Epub 2019 May 9.

4.

Progression of type 1 diabetes from the prediabetic stage is controlled by interferon-α signaling.

Marro BS, Ware BC, Zak J, de la Torre JC, Rosen H, Oldstone MB.

Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):3708-3713. doi: 10.1073/pnas.1700878114. Epub 2017 Mar 21.

5.

Cancer Genetics May Aid Diagnostics of Developmental Disorders.

Zak J, Schuster-Boeckler B, Bond G.

Hum Mutat. 2016 Oct;37(10):989. doi: 10.1002/humu.23068. No abstract available.

PMID:
27623404
6.

Aspp1: A Guardian of Hematopoietic Stem Cell Integrity.

Zak J, Lu X.

Cell Stem Cell. 2015 Jul 2;17(1):3-5. doi: 10.1016/j.stem.2015.06.012.

7.

Polemics on Ethical Aspects in the Compost Business.

Maroušek J, Hašková S, Zeman R, Žák J, Vaníčková R, Maroušková A, Váchal J, Myšková K.

Sci Eng Ethics. 2016 Apr;22(2):581-90. doi: 10.1007/s11948-015-9664-y. Epub 2015 May 31.

PMID:
26026968
8.

ASPP2 links the apical lateral polarity complex to the regulation of YAP activity in epithelial cells.

Royer C, Koch S, Qin X, Zak J, Buti L, Dudziec E, Zhong S, Ratnayaka I, Srinivas S, Lu X.

PLoS One. 2014 Oct 31;9(10):e111384. doi: 10.1371/journal.pone.0111384. eCollection 2014.

9.

ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1.

Wang Y, Bu F, Royer C, Serres S, Larkin JR, Soto MS, Sibson NR, Salter V, Fritzsche F, Turnquist C, Koch S, Zak J, Zhong S, Wu G, Liang A, Olofsen PA, Moch H, Hancock DC, Downward J, Goldin RD, Zhao J, Tong X, Guo Y, Lu X.

Nat Cell Biol. 2014 Nov;16(11):1092-104. doi: 10.1038/ncb3050. Epub 2014 Oct 26.

PMID:
25344754
10.

A code for RanGDP binding in ankyrin repeats defines a nuclear import pathway.

Lu M, Zak J, Chen S, Sanchez-Pulido L, Severson DT, Endicott J, Ponting CP, Schofield CJ, Lu X.

Cell. 2014 May 22;157(5):1130-45. doi: 10.1016/j.cell.2014.05.006.

11.

Chronic Obstructive Pulmonary Disease: official diagnosis and treatment guidelines of the Czech Pneumological and Phthisiological Society; a novel phenotypic approach to COPD with patient-oriented care.

Koblizek V, Chlumsky J, Zindr V, Neumannova K, Zatloukal J, Zak J, Sedlak V, Kocianova J, Zatloukal J, Hejduk K, Pracharova S; Czech Pneumological and Phthisiological Society.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2013 Jun;157(2):189-201. doi: 10.5507/bp.2013.039. Epub 2013 May 24.

12.

Establishing a flow process to coumarin-8-carbaldehydes as important synthetic scaffolds.

Zak J, Ron D, Riva E, Harding HP, Cross BC, Baxendale IR.

Chemistry. 2012 Aug 6;18(32):9901-10. doi: 10.1002/chem.201201039. Epub 2012 Jul 10.

PMID:
22782929
13.

The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule.

Cross BC, Bond PJ, Sadowski PG, Jha BK, Zak J, Goodman JM, Silverman RH, Neubert TA, Baxendale IR, Ron D, Harding HP.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):E869-78. doi: 10.1073/pnas.1115623109. Epub 2012 Feb 6.

14.

Envenoming by the viperid snake Proatheris superciliaris: a case report.

Valenta J, Stach Z, Fricova D, Zak J, Balik M.

Toxicon. 2008 Aug 1;52(2):392-4. doi: 10.1016/j.toxicon.2008.05.021. Epub 2008 Jun 13.

PMID:
18619480

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