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Items: 11

1.

Antitumor activity of Lepidium latifolium and identification of the epithionitrile 1-cyano-2,3-epithiopropane as its major active component.

Conde-Rioll M, Gajate C, Fernández JJ, Villa-Pulgarin JA, Napolitano JG, Norte M, Mollinedo F.

Mol Carcinog. 2018 Mar;57(3):347-360. doi: 10.1002/mc.22759. Epub 2017 Nov 14.

PMID:
29073716
2.

Mitochondria and lipid raft-located FOF1-ATP synthase as major therapeutic targets in the antileishmanial and anticancer activities of ether lipid edelfosine.

Villa-Pulgarín JA, Gajate C, Botet J, Jimenez A, Justies N, Varela-M RE, Cuesta-Marbán Á, Müller I, Modolell M, Revuelta JL, Mollinedo F.

PLoS Negl Trop Dis. 2017 Aug 22;11(8):e0005805. doi: 10.1371/journal.pntd.0005805. eCollection 2017 Aug.

3.

C-Geranylated flavonoids from Paulownia tomentosa fruits with antimicrobial potential and synergistic activity with antibiotics.

Navrátilová A, Nešuta O, Vančatová I, Čížek A, Varela-M RE, López-Abán J, Villa-Pulgarin JA, Mollinedo F, Muro A, Žemličková H, Kadlecová D, Šmejkal K.

Pharm Biol. 2016 Aug;54(8):1398-407. doi: 10.3109/13880209.2015.1103755. Epub 2016 Jan 20.

PMID:
26789098
4.

Complete inhibition of extranodal dissemination of lymphoma by edelfosine-loaded lipid nanoparticles.

Estella-Hermoso de Mendoza A, Campanero MA, Lana H, Villa-Pulgarin JA, de la Iglesia-Vicente J, Mollinedo F, Blanco-Prieto MJ.

Nanomedicine (Lond). 2012 May;7(5):679-90. doi: 10.2217/nnm.11.134.

5.

In vitro and in vivo efficacy of ether lipid edelfosine against Leishmania spp. and SbV-resistant parasites.

Varela-M RE, Villa-Pulgarin JA, Yepes E, Müller I, Modolell M, Muñoz DL, Robledo SM, Muskus CE, López-Abán J, Muro A, Vélez ID, Mollinedo F.

PLoS Negl Trop Dis. 2012;6(4):e1612. doi: 10.1371/journal.pntd.0001612. Epub 2012 Apr 10.

6.

New polyether triterpenoids from Laurencia viridis and their biological evaluation.

Pacheco FC, Villa-Pulgarin JA, Mollinedo F, Martín MN, Fernández JJ, Daranas AH.

Mar Drugs. 2011;9(11):2220-35. doi: 10.3390/md9112220. Epub 2011 Nov 7.

7.

Cytotoxic oxasqualenoids from the red alga Laurencia viridis.

Cen-Pacheco F, Villa-Pulgarin JA, Mollinedo F, Norte M, Daranas AH, Fernández JJ.

Eur J Med Chem. 2011 Aug;46(8):3302-8. doi: 10.1016/j.ejmech.2011.04.051. Epub 2011 Apr 29.

PMID:
21616566
8.

Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells.

Burgeiro A, Gajate C, Dakir el H, Villa-Pulgarín JA, Oliveira PJ, Mollinedo F.

Anticancer Drugs. 2011 Jul;22(6):507-18. doi: 10.1097/CAD.0b013e32834438f6.

PMID:
21527846
9.

Selective fusion of azurophilic granules with Leishmania-containing phagosomes in human neutrophils.

Mollinedo F, Janssen H, de la Iglesia-Vicente J, Villa-Pulgarin JA, Calafat J.

J Biol Chem. 2010 Nov 5;285(45):34528-36. doi: 10.1074/jbc.M110.125302. Epub 2010 Aug 26.

10.

Synthesis and cytotoxic activity of a new potential DNA bisintercalator: 1,4-Bis{3-[N-(4-chlorobenzo[g]phthalazin-1-yl)aminopropyl]}piperazine.

Galisteo J, Navarro P, Campayo L, Yunta MJ, Gómez-Contreras F, Villa-Pulgarin JA, Sierra BG, Mollinedo F, Gonzalez J, Garcia-España E.

Bioorg Med Chem. 2010 Jul 15;18(14):5301-9. doi: 10.1016/j.bmc.2010.05.053. Epub 2010 May 24.

PMID:
20538470
11.

In vitro and In vivo selective antitumor activity of Edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid rafts.

Mollinedo F, de la Iglesia-Vicente J, Gajate C, Estella-Hermoso de Mendoza A, Villa-Pulgarin JA, de Frias M, Roué G, Gil J, Colomer D, Campanero MA, Blanco-Prieto MJ.

Clin Cancer Res. 2010 Apr 1;16(7):2046-54. doi: 10.1158/1078-0432.CCR-09-2456. Epub 2010 Mar 16.

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