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Items: 1 to 20 of 37

1.

Human Pluripotent Stem Cell-Derived Hepatocytes Show Higher Transcriptional Correlation with Adult Liver Tissue than with Fetal Liver Tissue.

Ghosheh N, Küppers-Munther B, Asplund A, Andersson CX, Björquist P, Andersson TB, Carén H, Simonsson S, Sartipy P, Synnergren J.

ACS Omega. 2020 Mar 2;5(10):4816-4827. doi: 10.1021/acsomega.9b03514. eCollection 2020 Mar 17.

2.

Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases.

Holmgren G, Ulfenborg B, Asplund A, Toet K, Andersson CX, Hammarstedt A, Hanemaaijer R, Küppers-Munther B, Synnergren J.

Int J Mol Sci. 2020 Jan 11;21(2). pii: E469. doi: 10.3390/ijms21020469.

3.

Transcriptional sex and regional differences in paired human atrial and ventricular cardiac biopsies collected in vivo.

Synnergren J, Vukusic K, Dönnes P, Jonsson M, Lindahl A, Dellgren G, Jeppsson A, Asp J.

Physiol Genomics. 2020 Feb 1;52(2):110-120. doi: 10.1152/physiolgenomics.00036.2019. Epub 2019 Dec 23.

PMID:
31869284
4.

Enhanced xeno-free differentiation of hiPSC-derived astroglia applied in a blood-brain barrier model.

Delsing L, Kallur T, Zetterberg H, Hicks R, Synnergren J.

Fluids Barriers CNS. 2019 Aug 29;16(1):27. doi: 10.1186/s12987-019-0147-4.

5.

Diabetic Cardiomyopathy Modelling Using Induced Pluripotent Stem Cell Derived Cardiomyocytes: Recent Advances and Emerging Models.

Granéli C, Hicks R, Brolén G, Synnergren J, Sartipy P.

Stem Cell Rev Rep. 2019 Feb;15(1):13-22. doi: 10.1007/s12015-018-9858-1. Review.

6.

Barrier Properties and Transcriptome Expression in Human iPSC-Derived Models of the Blood-Brain Barrier.

Delsing L, Dönnes P, Sánchez J, Clausen M, Voulgaris D, Falk A, Herland A, Brolén G, Zetterberg H, Hicks R, Synnergren J.

Stem Cells. 2018 Dec;36(12):1816-1827. doi: 10.1002/stem.2908. Epub 2018 Nov 5.

7.

Human iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic Models.

Lundin A, Delsing L, Clausen M, Ricchiuto P, Sanchez J, Sabirsh A, Ding M, Synnergren J, Zetterberg H, Brolén G, Hicks R, Herland A, Falk A.

Stem Cell Reports. 2018 Mar 13;10(3):1030-1045. doi: 10.1016/j.stemcr.2018.01.021. Epub 2018 Feb 15.

8.

Expression Profiling of Human Pluripotent Stem Cell-Derived Cardiomyocytes Exposed to Doxorubicin-Integration and Visualization of Multi-Omics Data.

Holmgren G, Sartipy P, Andersson CX, Lindahl A, Synnergren J.

Toxicol Sci. 2018 May 1;163(1):182-195. doi: 10.1093/toxsci/kfy012.

PMID:
29385562
9.

CSF/serum albumin ratio in dementias: a cross-sectional study on 1861 patients.

Skillbäck T, Delsing L, Synnergren J, Mattsson N, Janelidze S, Nägga K, Kilander L, Hicks R, Wimo A, Winblad B, Hansson O, Blennow K, Eriksdotter M, Zetterberg H.

Neurobiol Aging. 2017 Nov;59:1-9. doi: 10.1016/j.neurobiolaging.2017.06.028. Epub 2017 Jul 11.

PMID:
28779628
10.

Comparative transcriptomics of hepatic differentiation of human pluripotent stem cells and adult human liver tissue.

Ghosheh N, Küppers-Munther B, Asplund A, Edsbagge J, Ulfenborg B, Andersson TB, Björquist P, Andersson CX, Carén H, Simonsson S, Sartipy P, Synnergren J.

Physiol Genomics. 2017 Aug 1;49(8):430-446. doi: 10.1152/physiolgenomics.00007.2017. Epub 2017 Jul 10.

11.

A data analysis framework for biomedical big data: Application on mesoderm differentiation of human pluripotent stem cells.

Ulfenborg B, Karlsson A, Riveiro M, Améen C, Åkesson K, Andersson CX, Sartipy P, Synnergren J.

PLoS One. 2017 Jun 27;12(6):e0179613. doi: 10.1371/journal.pone.0179613. eCollection 2017.

12.

Erratum to: Maintenance of drug metabolism and transport functions in human precision-cut liver slices during prolonged incubation for 5 days.

Starokozhko V, Vatakuti S, Schievink B, Merema MT, Asplund A, Synnergren J, Aspegren A, Groothuis GMM.

Arch Toxicol. 2017 Jul;91(7):2711. doi: 10.1007/s00204-016-1895-4. No abstract available.

13.

Comparative transcriptomic analysis identifies genes differentially expressed in human epicardial progenitors and hiPSC-derived cardiac progenitors.

Synnergren J, Drowley L, Plowright AT, Brolén G, Goumans MJ, Gittenberger-de Groot AC, Sartipy P, Wang QD.

Physiol Genomics. 2016 Nov 1;48(11):771-784. doi: 10.1152/physiolgenomics.00064.2016. Epub 2016 Sep 2.

14.

Maintenance of drug metabolism and transport functions in human precision-cut liver slices during prolonged incubation for 5 days.

Starokozhko V, Vatakuti S, Schievink B, Merema MT, Asplund A, Synnergren J, Aspegren A, Groothuis GMM.

Arch Toxicol. 2017 May;91(5):2079-2092. doi: 10.1007/s00204-016-1865-x. Epub 2016 Oct 7. Erratum in: Arch Toxicol. 2017 Jul;91(7):2711.

15.

MicroRNAs as potential biomarkers for doxorubicin-induced cardiotoxicity.

Holmgren G, Synnergren J, Andersson CX, Lindahl A, Sartipy P.

Toxicol In Vitro. 2016 Aug;34:26-34. doi: 10.1016/j.tiv.2016.03.009. Epub 2016 Apr 6.

PMID:
27033315
16.

Towards Creating the Perfect In Vitro Cell Model.

Jonsson MK, van Veen TA, Synnergren J, Becker B.

Stem Cells Int. 2016;2016:3459730. doi: 10.1155/2016/3459730. Epub 2016 Feb 3. No abstract available.

17.

Highly Synchronized Expression of Lineage-Specific Genes during In Vitro Hepatic Differentiation of Human Pluripotent Stem Cell Lines.

Ghosheh N, Olsson B, Edsbagge J, Küppers-Munther B, Van Giezen M, Asplund A, Andersson TB, Björquist P, Carén H, Simonsson S, Sartipy P, Synnergren J.

Stem Cells Int. 2016;2016:8648356. doi: 10.1155/2016/8648356. Epub 2016 Feb 1.

18.

Corrigendum to "Gene networks and transcription factor motifs defining the differentiation of human stem cells into hepatocyte-like cells" [J Hepatol 2015;63:934-942].

Godoy P, Schmidt-Heck W, Natarajan K, Lucendo-Villarin B, Szkolnicka D, Asplund A, Björquist P, Widera A, Stöber R, Campos G, Hammad S, Sachinidis A, Chaudhari U, Damm G, Weiss TS, Nüssler A, Synnergren J, Edlund K, Küppers-Munther B, Hay DC, Hengstler JG.

J Hepatol. 2016 Feb;64(2):525-526. doi: 10.1016/j.jhep.2015.11.003. Epub 2015 Dec 2. No abstract available.

19.

Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells.

Godoy P, Schmidt-Heck W, Natarajan K, Lucendo-Villarin B, Szkolnicka D, Asplund A, Björquist P, Widera A, Stöber R, Campos G, Hammad S, Sachinidis A, Chaudhari U, Damm G, Weiss TS, Nüssler A, Synnergren J, Edlund K, Küppers-Munther B, Hay DC, Hengstler JG.

J Hepatol. 2015 Oct;63(4):934-42. doi: 10.1016/j.jhep.2015.05.013. Epub 2015 May 25. Erratum in: J Hepatol. 2016 Feb;64(2):525-6. Erratum in: J Hepatol. 2016 Feb;64(2):525-526.

20.

Identification of stable reference genes in differentiating human pluripotent stem cells.

Holmgren G, Ghosheh N, Zeng X, Bogestål Y, Sartipy P, Synnergren J.

Physiol Genomics. 2015 Jun;47(6):232-9. doi: 10.1152/physiolgenomics.00130.2014. Epub 2015 Apr 7.

PMID:
25852171

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