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Items: 1 to 20 of 37

1.

Nanodrugs used in cancer therapy.

Kopeckova K, Eckschlager T, Sirc J, Hobzova R, Plch J, Hrabeta J, Michalek J.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2019 Jun;163(2):122-131. doi: 10.5507/bp.2019.010. Epub 2019 Apr 9.

2.

Ellipticine-loaded apoferritin nanocarrier retains DNA adduct-based cytochrome P450-facilitated toxicity in neuroblastoma cells.

Indra R, Černá T, Heger Z, Hraběta J, Wilhelm M, Dostálová S, Lengálová A, Martínková M, Adam V, Eckschlager T, Schmeiser HH, Arlt VM, Stiborová M.

Toxicology. 2019 May 1;419:40-54. doi: 10.1016/j.tox.2019.03.009. Epub 2019 Mar 23.

PMID:
30914192
3.

Cytometric analysis of cell suspension generated by cavitron ultrasonic surgical aspirator in pediatric brain tumors.

Vaskova M, Tichy M, Zamecnik J, Liby P, Kuzilkova D, Vicha A, Hrabeta J, Kalina T, Stary J, Hrusak O.

J Neurooncol. 2019 May;143(1):15-25. doi: 10.1007/s11060-019-03135-w. Epub 2019 Mar 2.

PMID:
30827009
4.

Poly(d,l-lactide)/polyethylene glycol micro/nanofiber mats as paclitaxel-eluting carriers: preparation and characterization of fibers, in vitro drug release, antiangiogenic activity and tumor recurrence prevention.

Hobzova R, Hampejsova Z, Cerna T, Hrabeta J, Venclikova K, Jedelska J, Bakowsky U, Bosakova Z, Lhotka M, Vaculin S, Franek M, Steinhart M, Kovarova J, Michalek J, Sirc J.

Mater Sci Eng C Mater Biol Appl. 2019 May;98:982-993. doi: 10.1016/j.msec.2019.01.046. Epub 2019 Jan 14.

PMID:
30813105
5.

Proteomic Signature of Neuroblastoma Cells UKF-NB-4 Reveals Key Role of Lysosomal Sequestration and the Proteasome Complex in Acquiring Chemoresistance to Cisplatin.

Merlos Rodrigo MA, Buchtelova H, de Los Rios V, Casal JI, Eckschlager T, Hrabeta J, Belhajova M, Heger Z, Adam V.

J Proteome Res. 2019 Mar 1;18(3):1255-1263. doi: 10.1021/acs.jproteome.8b00867. Epub 2019 Jan 11.

PMID:
30592607
6.

KDM5 demethylases and their role in cancer cell chemoresistance.

Plch J, Hrabeta J, Eckschlager T.

Int J Cancer. 2019 Jan 15;144(2):221-231. doi: 10.1002/ijc.31881. Epub 2018 Nov 26. Review.

PMID:
30246379
7.

Paclitaxel-Loaded Polylactide/Polyethylene Glycol Fibers with Long-Term Antitumor Activity as a Potential Drug Carrier for Local Chemotherapy.

Plch J, Venclikova K, Janouskova O, Hrabeta J, Eckschlager T, Kopeckova K, Hampejsova Z, Bosakova Z, Sirc J, Hobzova R.

Macromol Biosci. 2018 Jun;18(6):e1800011. doi: 10.1002/mabi.201800011. Epub 2018 Apr 24.

PMID:
29688614
8.

The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells.

Cerna T, Hrabeta J, Eckschlager T, Frei E, Schmeiser HH, Arlt VM, Stiborová M.

Int J Mol Sci. 2018 Jan 5;19(1). pii: E164. doi: 10.3390/ijms19010164.

9.

VPA does not enhance platinum binding to DNA in cisplatin-resistant neuroblastoma cancer cells.

Raudenska M, Krejcova L, Richtera L, Heger Z, Hrabeta J, Eckschlager T, Stiborova M, Adam V, Kratochvilova M, Masarik M, Gumulec J.

Tumour Biol. 2017 Sep;39(9):1010428317711656. doi: 10.1177/1010428317711656.

PMID:
28945187
10.

Histone Deacetylase Inhibitors as Anticancer Drugs.

Eckschlager T, Plch J, Stiborova M, Hrabeta J.

Int J Mol Sci. 2017 Jul 1;18(7). pii: E1414. doi: 10.3390/ijms18071414. Review.

11.

Zinc and zinc-containing biomolecules in childhood brain tumors.

Hrabeta J, Eckschlager T, Stiborova M, Heger Z, Krizkova S, Adam V.

J Mol Med (Berl). 2016 Nov;94(11):1199-1215. doi: 10.1007/s00109-016-1454-8. Epub 2016 Sep 16. Review.

PMID:
27638340
12.

Valproic Acid Increases CD133 Positive Cells that Show Low Sensitivity to Cytostatics in Neuroblastoma.

Khalil MA, Hraběta J, Groh T, Procházka P, Doktorová H, Eckschlager T.

PLoS One. 2016 Sep 14;11(9):e0162916. doi: 10.1371/journal.pone.0162916. eCollection 2016.

13.

Site-Directed Conjugation of Antibodies to Apoferritin Nanocarrier for Targeted Drug Delivery to Prostate Cancer Cells.

Dostalova S, Cerna T, Hynek D, Koudelkova Z, Vaculovic T, Kopel P, Hrabeta J, Heger Z, Vaculovicova M, Eckschlager T, Stiborova M, Adam V.

ACS Appl Mater Interfaces. 2016 Jun 15;8(23):14430-41. doi: 10.1021/acsami.6b04286. Epub 2016 Jun 2.

PMID:
27219717
14.

Overcoming multidrug resistance in Dox-resistant neuroblastoma cell lines via treatment with HPMA copolymer conjugates containing anthracyclines and P-gp inhibitors.

Koziolová E, Janoušková O, Cuchalová L, Hvězdová Z, Hraběta J, Eckschlager T, Sivák L, Ulbrich K, Etrych T, Šubr V.

J Control Release. 2016 Jul 10;233:136-46. doi: 10.1016/j.jconrel.2016.05.036. Epub 2016 May 14.

PMID:
27189135
15.

Metal Containing Cytostatics and Their Interaction with Cellular Thiol Compounds Causing Chemoresistance.

Hrabeta J, Adam V, Eckschlager T, Frei E, Stiborova M, Kizek R.

Anticancer Agents Med Chem. 2016;16(6):686-98. Review.

PMID:
26584725
16.

Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells.

Hrabeta J, Groh T, Khalil MA, Poljakova J, Adam V, Kizek R, Uhlik J, Doktorova H, Cerna T, Frei E, Stiborova M, Eckschlager T.

Int J Oncol. 2015 Sep;47(3):971-80. doi: 10.3892/ijo.2015.3066. Epub 2015 Jun 29.

PMID:
26134421
17.

Hypoxia-induced chemoresistance in cancer cells: The role of not only HIF-1.

Doktorova H, Hrabeta J, Khalil MA, Eckschlager T.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015 Jun;159(2):166-77. doi: 10.5507/bp.2015.025. Epub 2015 May 19. Review.

18.

The synergistic effects of DNA-damaging drugs cisplatin and etoposide with a histone deacetylase inhibitor valproate in high-risk neuroblastoma cells.

Groh T, Hrabeta J, Khalil MA, Doktorova H, Eckschlager T, Stiborova M.

Int J Oncol. 2015 Jul;47(1):343-52. doi: 10.3892/ijo.2015.2996. Epub 2015 May 11.

PMID:
25963435
19.

Hypoxia-mediated histone acetylation and expression of N-myc transcription factor dictate aggressiveness of neuroblastoma cells.

Poljaková J, Groh T, Gudino ZO, Hraběta J, Bořek-Dohalská L, Kizek R, Doktorová H, Eckschlager T, Stiborová M.

Oncol Rep. 2014 Apr;31(4):1928-34. doi: 10.3892/or.2014.2999. Epub 2014 Jan 27.

PMID:
24481548
20.

Histone deacetylase inhibitors in cancer therapy. A review.

Hrabeta J, Stiborova M, Adam V, Kizek R, Eckschlager T.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2014 Jun;158(2):161-9. doi: 10.5507/bp.2013.085. Epub 2013 Nov 21. Review.

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