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Items: 1 to 20 of 23


Mitochondrial damage pathways in ventilator induced lung injury (VILI): an update.

Parker JC.

J Lung Health Dis. 2018;2(2):18-22. Epub 2018 Apr 18.


Mitochondrial Targeted Endonuclease III DNA Repair Enzyme Protects against Ventilator Induced Lung Injury in Mice.

Hashizume M, Mouner M, Chouteau JM, Gorodnya OM, Ruchko MV, Wilson GL, Gillespie MN, Parker JC.

Pharmaceuticals (Basel). 2014 Aug 22;7(8):894-912. doi: 10.3390/ph7080894.


TRPV4 calcium entry and surface expression attenuated by inhibition of myosin light chain kinase in rat pulmonary microvascular endothelial cells.

Parker JC, Hashizumi M, Kelly SV, Francis M, Mouner M, Meyer AL, Townsley MI, Wu S, Cioffi DL, Taylor MS.

Physiol Rep. 2013 Oct;1(5):e00121. doi: 10.1002/phy2.121. Epub 2013 Oct 27.


Mitochondrial-targeted DNA repair enzyme 8-oxoguanine DNA glycosylase 1 protects against ventilator-induced lung injury in intact mice.

Hashizume M, Mouner M, Chouteau JM, Gorodnya OM, Ruchko MV, Potter BJ, Wilson GL, Gillespie MN, Parker JC.

Am J Physiol Lung Cell Mol Physiol. 2013 Feb 15;304(4):L287-97. doi: 10.1152/ajplung.00071.2012. Epub 2012 Dec 14.


Acute lung injury and pulmonary vascular permeability: use of transgenic models.

Parker JC.

Compr Physiol. 2011 Apr;1(2):835-82. doi: 10.1002/cphy.c100013. Review.


TRPV4 channels augment macrophage activation and ventilator-induced lung injury.

Hamanaka K, Jian MY, Townsley MI, King JA, Liedtke W, Weber DS, Eyal FG, Clapp MM, Parker JC.

Am J Physiol Lung Cell Mol Physiol. 2010 Sep;299(3):L353-62. doi: 10.1152/ajplung.00315.2009. Epub 2010 Jun 18.


Pulmonary vascular heterogeneity and the Starling hypothesis.

Effros RM, Parker JC.

Microvasc Res. 2009 Jun;78(1):71-7. doi: 10.1016/j.mvr.2009.03.004. Epub 2009 Mar 28. Review.


Rapid cooling preserves the ischaemic myocardium against mitochondrial damage and left ventricular dysfunction.

Tissier R, Couvreur N, Ghaleh B, Bruneval P, Lidouren F, Morin D, Zini R, Bize A, Chenoune M, Belair MF, Mandet C, Douheret M, Dubois-Rande JL, Parker JC, Cohen MV, Downey JM, Berdeaux A.

Cardiovasc Res. 2009 Jul 15;83(2):345-53. doi: 10.1093/cvr/cvp046. Epub 2009 Feb 5.


Physiological determinants of the pulmonary filtration coefficient.

Parker JC, Townsley MI.

Am J Physiol Lung Cell Mol Physiol. 2008 Aug;295(2):L235-7. doi: 10.1152/ajplung.00064.2008. Epub 2008 May 23. Review.


Pulmonary microvascular endothelial cells form a tighter monolayer when grown in chronic hypoxia.

Solodushko V, Parker JC, Fouty B.

Am J Respir Cell Mol Biol. 2008 Apr;38(4):491-7. Epub 2007 Nov 29.


Cytosolic phospholipase A2 and arachidonic acid metabolites modulate ventilator-induced permeability increases in isolated mouse lungs.

Miyahara T, Hamanaka K, Weber DS, Anghelescu M, Frost JR, King JA, Parker JC.

J Appl Physiol (1985). 2008 Feb;104(2):354-62. Epub 2007 Nov 15.


TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs.

Hamanaka K, Jian MY, Weber DS, Alvarez DF, Townsley MI, Al-Mehdi AB, King JA, Liedtke W, Parker JC.

Am J Physiol Lung Cell Mol Physiol. 2007 Oct;293(4):L923-32. Epub 2007 Jul 27.


Reduction in alveolar macrophages attenuates acute ventilator induced lung injury in rats.

Eyal FG, Hamm CR, Parker JC.

Intensive Care Med. 2007 Jul;33(7):1212-1218. doi: 10.1007/s00134-007-0651-x. Epub 2007 Apr 28.


Phosphoinositide 3-kinase, Src, and Akt modulate acute ventilation-induced vascular permeability increases in mouse lungs.

Miyahara T, Hamanaka K, Weber DS, Drake DA, Anghelescu M, Parker JC.

Am J Physiol Lung Cell Mol Physiol. 2007 Jul;293(1):L11-21. Epub 2007 Feb 23.


Total liquid ventilation provides ultra-fast cardioprotective cooling.

Tissier R, Hamanaka K, Kuno A, Parker JC, Cohen MV, Downey JM.

J Am Coll Cardiol. 2007 Feb 6;49(5):601-5. Epub 2007 Jan 22.


Hydraulic conductance of lung endothelial phenotypes and Starling safety factors against edema.

Parker JC.

Am J Physiol Lung Cell Mol Physiol. 2007 Feb;292(2):L378-80. Epub 2006 Oct 13.


Hydraulic conductance of pulmonary microvascular and macrovascular endothelial cell monolayers.

Parker JC, Stevens T, Randall J, Weber DS, King JA.

Am J Physiol Lung Cell Mol Physiol. 2006 Jul;291(1):L30-7.


Differential responses of pulmonary endothelial phenotypes to cyclical stretch.

Adkison JB, Miller GT, Weber DS, Miyahara T, Ballard ST, Frost JR, Parker JC.

Microvasc Res. 2006 May;71(3):175-84. Epub 2006 Apr 19.


Restoration of mucociliary transport in the fluid-depleted trachea by surface-active instillates.

Ballard ST, Parker JC, Hamm CR.

Am J Respir Cell Mol Biol. 2006 Apr;34(4):500-4. Epub 2005 Dec 15.


Clara cell secretory protein and phospholipase A2 activity modulate acute ventilator-induced lung injury in mice.

Yoshikawa S, Miyahara T, Reynolds SD, Stripp BR, Anghelescu M, Eyal FG, Parker JC.

J Appl Physiol (1985). 2005 Apr;98(4):1264-71. Epub 2004 Dec 17.

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