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Items: 1 to 20 of 186


Arctiin is a pharmacological inhibitor of STAT3 phosphorylation at tyrosine 705 residue and potentiates bortezomib-induced apoptotic and anti-angiogenic effects in human multiple myeloma cells.

Lee JH, Kim C, Lee J, Um JY, Sethi G, Ahn KS.

Phytomedicine. 2018 Aug 11;55:282-292. doi: 10.1016/j.phymed.2018.06.038. [Epub ahead of print]


Platycodin D, a novel activator of AMP-activated protein kinase, attenuates obesity in db/db mice via regulation of adipogenesis and thermogenesis.

Kim HL, Park J, Jung Y, Ahn KS, Um JY.

Phytomedicine. 2019 Jan;52:254-263. doi: 10.1016/j.phymed.2018.09.227. Epub 2018 Sep 27.


Synergistic Effect of Bupleuri Radix and Scutellariae Radix on Adipogenesis and AMP-Activated Protein Kinase: A Network Pharmacological Approach.

Lee J, Park J, Park H, Youn DH, Lee J, Hong S, Um JY.

Evid Based Complement Alternat Med. 2018 Aug 23;2018:5269731. doi: 10.1155/2018/5269731. eCollection 2018.


Berberine Improves Benign Prostatic Hyperplasia via Suppression of 5 Alpha Reductase and Extracellular Signal-Regulated Kinase in Vivo and in Vitro.

Youn DH, Park J, Kim HL, Jung Y, Kang J, Lim S, Song G, Kwak HJ, Um JY.

Front Pharmacol. 2018 Jul 16;9:773. doi: 10.3389/fphar.2018.00773. eCollection 2018.


Bergamottin Suppresses Metastasis of Lung Cancer Cells through Abrogation of Diverse Oncogenic Signaling Cascades and Epithelial-to-Mesenchymal Transition.

Ko JH, Nam D, Um JY, Jung SH, Sethi G, Ahn KS.

Molecules. 2018 Jul 2;23(7). pii: E1601. doi: 10.3390/molecules23071601.


Anti-myeloma Effects of Icariin Are Mediated Through the Attenuation of JAK/STAT3-Dependent Signaling Cascade.

Jung YY, Lee JH, Nam D, Narula AS, Namjoshi OA, Blough BE, Um JY, Sethi G, Ahn KS.

Front Pharmacol. 2018 May 30;9:531. doi: 10.3389/fphar.2018.00531. eCollection 2018.


Formononetin-induced oxidative stress abrogates the activation of STAT3/5 signaling axis and suppresses the tumor growth in multiple myeloma preclinical model.

Kim C, Lee SG, Yang WM, Arfuso F, Um JY, Kumar AP, Bian J, Sethi G, Ahn KS.

Cancer Lett. 2018 Sep 1;431:123-141. doi: 10.1016/j.canlet.2018.05.038. Epub 2018 May 29.


Corrigendum to 'Secoisolariciresinol diglucoside inhibits adipogenesis through the AMPK pathway' [European Journal of Pharmacology (2018) 820:235-244].

Kang J, Park J, Kim HL, Jung Y, Youn DH, Lim S, Song G, Park H, Jin JS, Kwak HJ, Um JY.

Eur J Pharmacol. 2018 Jul 5;830:139. doi: 10.1016/j.ejphar.2018.05.012. No abstract available.


Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo.

Leem E, Kim HJ, Choi M, Kim S, Oh YS, Lee KJ, Choe YS, Um JY, Shin WH, Jeong JY, Jin BK, Kim DW, McLean C, Fisher PB, Kholodilov N, Ahn KS, Lee JM, Jung UJ, Lee SG, Kim SR.

Cell Death Dis. 2018 May 1;9(5):449. doi: 10.1038/s41419-018-0491-3.


Bergamottin Inhibits Adipogenesis in 3T3-L1 Cells and Weight Regulation in Diet-Induced Obese Mice.

Ko JH, Nam D, Um JY, Jung SH, Ahn KS.

Am J Chin Med. 2018;46(3):601-615. doi: 10.1142/S0192415X18500313. Epub 2018 Apr 4.


Pharmacological effect of prohibited combination pair Panax ginseng and Veratrum nigrum on colorectal metastasis in vitro and in vivo.

Kee JY, Han YH, Mun JG, Um JY, Hong SH.

J Ethnopharmacol. 2018 Jun 28;220:177-187. doi: 10.1016/j.jep.2018.03.036. Epub 2018 Mar 28.


The Application of Embelin for Cancer Prevention and Therapy.

Ko JH, Lee SG, Yang WM, Um JY, Sethi G, Mishra S, Shanmugam MK, Ahn KS.

Molecules. 2018 Mar 9;23(3). pii: E621. doi: 10.3390/molecules23030621. Review.


Ophiopogonin D modulates multiple oncogenic signaling pathways, leading to suppression of proliferation and chemosensitization of human lung cancer cells.

Lee JH, Kim C, Lee SG, Yang WM, Um JY, Sethi G, Ahn KS.

Phytomedicine. 2018 Feb 1;40:165-175. doi: 10.1016/j.phymed.2018.01.002. Epub 2018 Jan 12.


Secoisolariciresinol diglucoside inhibits adipogenesis through the AMPK pathway.

Kang J, Park J, Kim HL, Jung Y, Youn DH, Lim S, Song G, Park H, Jin JS, Kwak HJ, Um JY.

Eur J Pharmacol. 2018 Feb 5;820:235-244. doi: 10.1016/j.ejphar.2017.12.038. Epub 2017 Dec 18. Erratum in: Eur J Pharmacol. 2018 Jul 5;830:139.


The Role of Resveratrol in Cancer Therapy.

Ko JH, Sethi G, Um JY, Shanmugam MK, Arfuso F, Kumar AP, Bishayee A, Ahn KS.

Int J Mol Sci. 2017 Dec 1;18(12). pii: E2589. doi: 10.3390/ijms18122589. Review.


Vanillic acid attenuates testosterone-induced benign prostatic hyperplasia in rats and inhibits proliferation of prostatic epithelial cells.

Jung Y, Park J, Kim HL, Youn DH, Kang J, Lim S, Jeong MY, Sethi G, Park SJ, Ahn KS, Um JY.

Oncotarget. 2017 Aug 3;8(50):87194-87208. doi: 10.18632/oncotarget.19909. eCollection 2017 Oct 20.


Vanillic acid attenuates obesity via activation of the AMPK pathway and thermogenic factors in vivo and in vitro.

Jung Y, Park J, Kim HL, Sim JE, Youn DH, Kang J, Lim S, Jeong MY, Yang WM, Lee SG, Ahn KS, Um JY.

FASEB J. 2018 Mar;32(3):1388-1402. doi: 10.1096/fj.201700231RR.


Farnesol Has an Anti-obesity Effect in High-Fat Diet-Induced Obese Mice and Induces the Development of Beige Adipocytes in Human Adipose Tissue Derived-Mesenchymal Stem Cells.

Kim HL, Jung Y, Park J, Youn DH, Kang J, Lim S, Lee BS, Jeong MY, Choe SK, Park R, Ahn KS, Um JY.

Front Pharmacol. 2017 Sep 20;8:654. doi: 10.3389/fphar.2017.00654. eCollection 2017.


Arctii Fructus Inhibits Colorectal Cancer Cell Proliferation and MMPs Mediated Invasion via AMPK.

Han YH, Kee JY, Kim DS, Mun JG, Park SH, Kim YJ, Um JY, Hong SH.

Am J Chin Med. 2017;45(6):1309-1325. doi: 10.1142/S0192415X17500720. Epub 2017 Aug 22.


Albiflorin ameliorates obesity by inducing thermogenic genes via AMPK and PI3K/AKT in vivo and in vitro.

Jeong MY, Park J, Youn DH, Jung Y, Kang J, Lim S, Kang MW, Kim HL, So HS, Park R, Hong SH, Um JY.

Metabolism. 2017 Aug;73:85-99. doi: 10.1016/j.metabol.2017.05.009. Epub 2017 May 31.


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