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Items: 1 to 20 of 32


Monocytes as Endothelial Progenitor Cells (EPCs), Another Brick in the Wall to Disentangle Tumor Angiogenesis.

Lopes-Coelho F, Silva F, Gouveia-Fernandes S, Martins C, Lopes N, Domingues G, Brito C, Almeida AM, Pereira SA, Serpa J.

Cells. 2020 Jan 1;9(1). pii: E107. doi: 10.3390/cells9010107.


Metabolic Remodelling: An Accomplice for New Therapeutic Strategies to Fight Lung Cancer.

Mendes C, Serpa J.

Antioxidants (Basel). 2019 Nov 29;8(12). pii: E603. doi: 10.3390/antiox8120603. Review.


Targeting Glutathione and Cystathionine β-Synthase in Ovarian Cancer Treatment by Selenium-Chrysin Polyurea Dendrimer Nanoformulation.

Santos I, Ramos C, Mendes C, Sequeira CO, Tomé CS, Fernandes DGH, Mota P, Pires RF, Urso D, Hipólito A, Antunes AMM, Vicente JB, Pereira SA, Bonifácio VDB, Nunes SC, Serpa J.

Nutrients. 2019 Oct 19;11(10). pii: E2523. doi: 10.3390/nu11102523.


Unraveling FATP1, regulated by ER-β, as a targeted breast cancer innovative therapy.

Mendes C, Lopes-Coelho F, Ramos C, Martins F, Santos I, Rodrigues A, Silva F, André S, Serpa J.

Sci Rep. 2019 Oct 1;9(1):14107. doi: 10.1038/s41598-019-50531-3.


Arl13b Regulates Breast Cancer Cell Migration and Invasion by Controlling Integrin-Mediated Signaling.

Casalou C, Faustino A, Silva F, Ferreira IC, Vaqueirinho D, Ferreira A, Castanheira P, Barona T, Ramalho JS, Serpa J, Félix A, Barral DC.

Cancers (Basel). 2019 Sep 29;11(10). pii: E1461. doi: 10.3390/cancers11101461.


l-Buthionine Sulfoximine Detection and Quantification in Polyurea Dendrimer Nanoformulations.

Mota P, Pires RF, Serpa J, Bonifácio VDB.

Molecules. 2019 Aug 27;24(17). pii: E3111. doi: 10.3390/molecules24173111.


A Metabolomics-Inspired Strategy for the Identification of Protein Covalent Modifications.

Nunes J, Charneira C, Nunes C, Gouveia-Fernandes S, Serpa J, Morello J, Antunes AMM.

Front Chem. 2019 Jul 31;7:532. doi: 10.3389/fchem.2019.00532. eCollection 2019.


Acetylation drives hepatocyte nuclear factor 1β stability by blocking proteasome-mediated degradation.

Lopes-Coelho F, Silva F, Hipólito A, Cardoso BA, Serpa J.

J Cell Biochem. 2019 Jun;120(6):9337-9344. doi: 10.1002/jcb.28209. Epub 2018 Dec 7.


Cysteine Oxidative Dynamics Underlies Hypertension and Kidney Dysfunction Induced by Chronic Intermittent Hypoxia.

Coelho NR, Dias CG, João Correia M, Grácio P, Serpa J, Monteiro EC, Diogo LN, Pereira SA.

Adv Exp Med Biol. 2018;1071:83-88. doi: 10.1007/978-3-319-91137-3_10.


Glutathione in Ovarian Cancer: A Double-Edged Sword.

Nunes SC, Serpa J.

Int J Mol Sci. 2018 Jun 26;19(7). pii: E1882. doi: 10.3390/ijms19071882. Review.


Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity.

Nunes SC, Ramos C, Lopes-Coelho F, Sequeira CO, Silva F, Gouveia-Fernandes S, Rodrigues A, Guimarães A, Silveira M, Abreu S, Santo VE, Brito C, Félix A, Pereira SA, Serpa J.

Sci Rep. 2018 Jun 22;8(1):9513. doi: 10.1038/s41598-018-27753-y.


Cysteine boosters the evolutionary adaptation to CoCl2 mimicked hypoxia conditions, favouring carboplatin resistance in ovarian cancer.

Nunes SC, Lopes-Coelho F, Gouveia-Fernandes S, Ramos C, Pereira SA, Serpa J.

BMC Evol Biol. 2018 Jun 19;18(1):97. doi: 10.1186/s12862-018-1214-1.


Revisiting the Crabtree/Warburg effect in a dynamic perspective: a fitness advantage against sugar-induced cell death.

de Alteriis E, Cartenì F, Parascandola P, Serpa J, Mazzoleni S.

Cell Cycle. 2018;17(6):688-701. doi: 10.1080/15384101.2018.1442622. Review.


Metabolic cooperation between cancer and non-cancerous stromal cells is pivotal in cancer progression.

Lopes-Coelho F, Gouveia-Fernandes S, Serpa J.

Tumour Biol. 2018 Feb;40(2):1010428318756203. doi: 10.1177/1010428318756203. Review.


Monocarboxylate transporter 1 (MCT1), a tool to stratify acute myeloid leukemia (AML) patients and a vehicle to kill cancer cells.

Lopes-Coelho F, Nunes C, Gouveia-Fernandes S, Rosas R, Silva F, Gameiro P, Carvalho T, Gomes da Silva M, Cabeçadas J, Dias S, Gonçalves LG, Serpa J.

Oncotarget. 2017 Aug 16;8(47):82803-82823. doi: 10.18632/oncotarget.20294. eCollection 2017 Oct 10.


Unmasking efavirenz neurotoxicity: Time matters to the underlying mechanisms.

Grilo NM, João Correia M, Miranda JP, Cipriano M, Serpa J, Matilde Marques M, Monteiro EC, Antunes AMM, Diogo LN, Pereira SA.

Eur J Pharm Sci. 2017 Jul 15;105:47-54. doi: 10.1016/j.ejps.2017.05.010. Epub 2017 May 6.


Breast cancer metabolic cross-talk: Fibroblasts are hubs and breast cancer cells are gatherers of lipids.

Lopes-Coelho F, André S, Félix A, Serpa J.

Mol Cell Endocrinol. 2018 Feb 15;462(Pt B):93-106. doi: 10.1016/j.mce.2017.01.031. Epub 2017 Jan 22.


Functional redundancy of the Notch pathway in ovarian cancer cell lines.

Silva F, Félix A, Serpa J.

Oncol Lett. 2016 Oct;12(4):2686-2691. Epub 2016 Aug 5.


STAT3:FOXM1 and MCT1 drive uterine cervix carcinoma fitness to a lactate-rich microenvironment.

Silva LS, Goncalves LG, Silva F, Domingues G, Maximo V, Ferreira J, Lam EW, Dias S, Felix A, Serpa J.

Tumour Biol. 2016 Apr;37(4):5385-95. doi: 10.1007/s13277-015-4385-z. Epub 2015 Nov 12.


HNF1β drives glutathione (GSH) synthesis underlying intrinsic carboplatin resistance of ovarian clear cell carcinoma (OCCC).

Lopes-Coelho F, Gouveia-Fernandes S, Gonçalves LG, Nunes C, Faustino I, Silva F, Félix A, Pereira SA, Serpa J.

Tumour Biol. 2016 Apr;37(4):4813-29. doi: 10.1007/s13277-015-4290-5. Epub 2015 Oct 31.


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