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Items: 1 to 20 of 172


Role of Sulfonylurea Receptor 1 and Glibenclamide in Traumatic Brain Injury: A Review of the Evidence.

Jha RM, Bell J, Citerio G, Hemphill JC, Kimberly WT, Narayan RK, Sahuquillo J, Sheth KN, Simard JM.

Int J Mol Sci. 2020 Jan 9;21(2). pii: E409. doi: 10.3390/ijms21020409. Review.


Emerging Pharmacological Treatments for Cerebral Edema: Evidence from Clinical Studies.

Stokum JA, Gerzanich V, Sheth KN, Kimberly WT, Simard JM.

Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:291-309. doi: 10.1146/annurev-pharmtox-010919-023429.


SUR1-TRPM4 channels, not KATP, mediate brain swelling following cerebral ischemia.

Woo SK, Tsymbalyuk N, Tsymbalyuk O, Ivanova S, Gerzanich V, Simard JM.

Neurosci Lett. 2019 Dec 31;718:134729. doi: 10.1016/j.neulet.2019.134729. [Epub ahead of print] Review.


Anti-edema and antioxidant combination therapy for ischemic stroke via glyburide-loaded betulinic acid nanoparticles.

Deng G, Ma C, Zhao H, Zhang S, Liu J, Liu F, Chen Z, Chen AT, Yang X, Avery J, Zou P, Du F, Lim KP, Holden D, Li S, Carson RE, Huang Y, Chen Q, Kimberly WT, Simard JM, Sheth KN, Zhou J.

Theranostics. 2019 Sep 21;9(23):6991-7002. doi: 10.7150/thno.35791. eCollection 2019.


BIIB093 (IV glibenclamide): an investigational compound for the prevention and treatment of severe cerebral edema.

Pergakis M, Badjatia N, Chaturvedi S, Cronin CA, Kimberly WT, Sheth KN, Simard JM.

Expert Opin Investig Drugs. 2019 Dec;28(12):1031-1040. doi: 10.1080/13543784.2019.1681967. Epub 2019 Oct 24. Review.


Brivaracetam attenuates pain behaviors in a murine model of neuropathic pain.

Tsymbalyuk S, Smith M, Gore C, Tsymbalyuk O, Ivanova S, Sansur C, Gerzanich V, Simard JM.

Mol Pain. 2019 Jan-Dec;15:1744806919886503. doi: 10.1177/1744806919886503. No abstract available.


Intravenous Glibenclamide Reduces Lesional Water Uptake in Large Hemispheric Infarction.

Vorasayan P, Bevers MB, Beslow LA, Sze G, Molyneaux BJ, Hinson HE, Simard JM, von Kummer R, Sheth KN, Kimberly WT.

Stroke. 2019 Nov;50(11):3021-3027. doi: 10.1161/STROKEAHA.119.026036. Epub 2019 Sep 20.


Utility of the Hijdra Sum Score in Predicting Risk of Aneurysm in Patients With Subarachnoid Hemorrhage: A Single-Center Experience With 550 Patients.

Kole MJ, Shea P, Albrecht JS, Cannarsa GJ, Wessell AP, Miller TR, Jindal G, Gandhi D, Aldrich EF, Simard JM.

Neurosurgery. 2019 Sep 9. pii: nyz346. doi: 10.1093/neuros/nyz346. [Epub ahead of print]


Iodine-based Dual-Energy CT of Traumatic Hemorrhagic Contusions: Relationship to In-Hospital Mortality and Short-term Outcome.

Bodanapally UK, Shanmuganathan K, Ramaswamy M, Tsymbalyuk S, Aarabi B, Parikh GY, Schwartzbauer G, Dreizin D, Simard JM, Ptak T, Li G, Liang Y, Fleiter TR.

Radiology. 2019 Sep;292(3):730-738. doi: 10.1148/radiol.2019190078. Epub 2019 Jul 30.


Magnetic Resonance Imaging Pilot Study of Intravenous Glyburide in Traumatic Brain Injury.

Eisenberg HM, Shenton ME, Pasternak O, Simard JM, Okonkwo DO, Aldrich C, He F, Jain S, Hayman EG.

J Neurotrauma. 2020 Jan 1;37(1):185-193. doi: 10.1089/neu.2019.6538. Epub 2019 Aug 27.


Efficacy of Ultra-Early (< 12 h), Early (12-24 h), and Late (>24-138.5 h) Surgery with Magnetic Resonance Imaging-Confirmed Decompression in American Spinal Injury Association Impairment Scale Grades A, B, and C Cervical Spinal Cord Injury.

Aarabi B, Akhtar-Danesh N, Chryssikos T, Shanmuganathan K, Schwartzbauer GT, Simard JM, Olexa J, Sansur CA, Crandall KM, Mushlin H, Kole MJ, Le EJ, Wessell AP, Pratt N, Cannarsa G, Lomangino C, Scarboro M, Aresco C, Oliver J, Caffes N, Carbine S, Mori K.

J Neurotrauma. 2019 Aug 1. doi: 10.1089/neu.2019.6606. [Epub ahead of print]


Chronic pain after blast-induced traumatic brain injury in awake rats.

Uddin O, Studlack PE, Parihar S, Keledjian K, Cruz A, Farooq T, Shin N, Gerzanich V, Simard JM, Keller A.

Neurobiol Pain. 2019 Apr 2;6:100030. doi: 10.1016/j.ynpai.2019.100030. eCollection 2019 Aug-Dec.


Minimally Invasive Surgery for Spontaneous Cerebellar Hemorrhage: A Multicenter Study.

Khattar NK, Fortuny EM, Wessell AP, John KD, Bak E, Adams SW, Meyer KS, Schirmer CM, Simard JM, Neimat JS, Ding D, James RF.

World Neurosurg. 2019 Sep;129:e35-e39. doi: 10.1016/j.wneu.2019.04.164. Epub 2019 Apr 28.


Pipeline embolization device diameter is an important factor determining the efficacy of flow diversion treatment of small intracranial saccular aneurysms.

Kole MJ, Miller TR, Cannarsa G, Wessell A, Jones S, Le E, Jindal G, Aldrich F, Simard JM, Gandhi D.

J Neurointerv Surg. 2019 Oct;11(10):1004-1008. doi: 10.1136/neurintsurg-2019-014792. Epub 2019 Mar 29.


Winners, losers, and controls.

Simard JM.

Neurology. 2019 Apr 9;92(15):689-690. doi: 10.1212/WNL.0000000000007257. Epub 2019 Mar 20. No abstract available.


Bursting at the Seams: Molecular Mechanisms Mediating Astrocyte Swelling.

Lafrenaye AD, Simard JM.

Int J Mol Sci. 2019 Jan 15;20(2). pii: E330. doi: 10.3390/ijms20020330. Review.


Effect of IV glyburide on adjudicated edema endpoints in the GAMES-RP Trial.

Kimberly WT, Bevers MB, von Kummer R, Demchuk AM, Romero JM, Elm JJ, Hinson HE, Molyneaux BJ, Simard JM, Sheth KN.

Neurology. 2018 Dec 4;91(23):e2163-e2169. doi: 10.1212/WNL.0000000000006618. Epub 2018 Nov 16.


Blast-induced brain injury in rats leads to transient vestibulomotor deficits and persistent orofacial pain.

Studlack PE, Keledjian K, Farooq T, Akintola T, Gerzanich V, Simard JM, Keller A.

Brain Inj. 2018;32(13-14):1866-1878. doi: 10.1080/02699052.2018.1536282. Epub 2018 Oct 22.


Extent of Spinal Cord Decompression in Motor Complete (American Spinal Injury Association Impairment Scale Grades A and B) Traumatic Spinal Cord Injury Patients: Post-Operative Magnetic Resonance Imaging Analysis of Standard Operative Approaches.

Aarabi B, Olexa J, Chryssikos T, Galvagno SM, Hersh DS, Wessell A, Sansur C, Schwartzbauer G, Crandall K, Shanmuganathan K, Simard JM, Mushlin H, Kole M, Le E, Pratt N, Cannarsa G, Lomangino CD, Scarboro M, Aresco C, Curry B.

J Neurotrauma. 2019 Mar 19;36(6):862-876. doi: 10.1089/neu.2018.5834. Epub 2018 Oct 9.

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