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Author Correction: The effect of endothelial nitric oxide synthase on the hemodynamics and wall mechanics in murine arteriovenous fistulas.

Pike D, Shiu YT, Cho YF, Le H, Somarathna M, Isayeva T, Guo L, Symons JD, Kevil CG, Totenhagen J, Lee T.

Sci Rep. 2019 Oct 24;9(1):15555. doi: 10.1038/s41598-019-51080-5.


Effect of Continuous-Flow Left Ventricular Assist Device Support on Coronary Artery Endothelial Function in Ischemic and Nonischemic Cardiomyopathy.

Symons JD, Deeter L, Deeter N, Bonn T, Cho JM, Ferrin P, McCreath L, Diakos NA, Taleb I, Alharethi R, McKellar S, Wever-Pinzon O, Navankasattusas S, Selzman CH, Fang JC, Drakos SG.

Circ Heart Fail. 2019 Aug;12(8):e006085. doi: 10.1161/CIRCHEARTFAILURE.119.006085. Epub 2019 Aug 19.


The effect of endothelial nitric oxide synthase on the hemodynamics and wall mechanics in murine arteriovenous fistulas.

Pike D, Shiu YT, Cho YF, Le H, Somarathna M, Isayeva T, Guo L, Symons JD, Kevil CG, Totenhagen J, Lee T.

Sci Rep. 2019 Mar 12;9(1):4299. doi: 10.1038/s41598-019-40683-7. Erratum in: Sci Rep. 2019 Oct 24;9(1):15555.


Dietary supplementation with strawberry induces marked changes in the composition and functional potential of the gut microbiome in diabetic mice.

Petersen C, Wankhade UD, Bharat D, Wong K, Mueller JE, Chintapalli SV, Piccolo BD, Jalili T, Jia Z, Symons JD, Shankar K, Anandh Babu PV.

J Nutr Biochem. 2019 Apr;66:63-69. doi: 10.1016/j.jnutbio.2019.01.004. Epub 2019 Jan 18.


Elevated arterial shear rate increases indexes of endothelial cell autophagy and nitric oxide synthase activation in humans.

Park SK, La Salle DT, Cerbie J, Cho JM, Bledsoe A, Nelson A, Morgan DE, Richardson RS, Shiu YT, Boudina S, Trinity JD, Symons JD.

Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H106-H112. doi: 10.1152/ajpheart.00561.2018. Epub 2018 Nov 9.


Soluble (pro)renin receptor as a potential therapy for diabetes insipidus.

Yang KT, Yang T, Symons JD.

Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1416-F1421. doi: 10.1152/ajprenal.00266.2018. Epub 2018 Jul 18. Review.


Circulating metabolites of strawberry mediate reductions in vascular inflammation and endothelial dysfunction in db/db mice.

Petersen C, Bharat D, Cutler BR, Gholami S, Denetso C, Mueller JE, Cho JM, Kim JS, Symons JD, Anandh Babu PV.

Int J Cardiol. 2018 Jul 15;263:111-117. doi: 10.1016/j.ijcard.2018.04.040. Epub 2018 Apr 12.


Commentaries on Viewpoint: Origin of the forward-going "backward" wave.

Hydren JR, Richardson RS, Symons JD, Mynard JP, Smolich JJ, Ramos JS, Dias KA, Dalleck LC, Drummond C, Westerhof B, Westerhof N, Zuo L, Zhou T.

J Appl Physiol (1985). 2017 Nov 1;123(5):1408-1410. doi: 10.1152/japplphysiol.00758.2017. No abstract available.


Blueberry Metabolites Attenuate Lipotoxicity-Induced Endothelial Dysfunction.

Bharat D, Cavalcanti RRM, Petersen C, Begaye N, Cutler BR, Costa MMA, Ramos RKLG, Ferreira MR, Li Y, Bharath LP, Toolson E, Sebahar P, Looper RE, Jalili T, Rajasekaran NS, Jia Z, Symons JD, Anandh Babu PV.

Mol Nutr Food Res. 2018 Jan;62(2). doi: 10.1002/mnfr.201700601. Epub 2017 Dec 14.


Endothelial Cell Autophagy Maintains Shear Stress-Induced Nitric Oxide Generation via Glycolysis-Dependent Purinergic Signaling to Endothelial Nitric Oxide Synthase.

Bharath LP, Cho JM, Park SK, Ruan T, Li Y, Mueller R, Bean T, Reese V, Richardson RS, Cai J, Sargsyan A, Pires K, Anandh Babu PV, Boudina S, Graham TE, Symons JD.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1646-1656. doi: 10.1161/ATVBAHA.117.309510. Epub 2017 Jul 6.


γ-Carboxyethyl hydroxychroman, a metabolite of γ-tocopherol, preserves nitric oxide bioavailability in endothelial cells challenged with high glucose.

Li Y, Bharath LP, Qian Y, Ruan T, Anandh Babu PV, Bruno RS, Symons JD, Jalili T.

Exp Biol Med (Maywood). 2016 Dec;241(18):2056-2062. doi: 10.1177/1535370216661780. Epub 2016 Jul 28.


Exercise training improves vascular mitochondrial function.

Park SY, Rossman MJ, Gifford JR, Bharath LP, Bauersachs J, Richardson RS, Abel ED, Symons JD, Riehle C.

Am J Physiol Heart Circ Physiol. 2016 Apr 1;310(7):H821-9. doi: 10.1152/ajpheart.00751.2015. Epub 2016 Jan 29.


Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo.

Bharath LP, Ruan T, Li Y, Ravindran A, Wan X, Nhan JK, Walker ML, Deeter L, Goodrich R, Johnson E, Munday D, Mueller R, Kunz D, Jones D, Reese V, Summers SA, Babu PV, Holland WL, Zhang QJ, Abel ED, Symons JD.

Diabetes. 2015 Nov;64(11):3914-26. doi: 10.2337/db15-0244. Epub 2015 Aug 7.


MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intolerance.

Kwon OS, Tanner RE, Barrows KM, Runtsch M, Symons JD, Jalili T, Bikman BT, McClain DA, O'Connell RM, Drummond MJ.

Am J Physiol Endocrinol Metab. 2015 Jul 1;309(1):E11-21. doi: 10.1152/ajpendo.00124.2015. Epub 2015 May 12.


Increased dihydroceramide/ceramide ratio mediated by defective expression of degs1 impairs adipocyte differentiation and function.

Barbarroja N, Rodriguez-Cuenca S, Nygren H, Camargo A, Pirraco A, Relat J, Cuadrado I, Pellegrinelli V, Medina-Gomez G, Lopez-Pedrera C, Tinahones FJ, Symons JD, Summers SA, Oresic M, Vidal-Puig A.

Diabetes. 2015 Apr;64(4):1180-92. doi: 10.2337/db14-0359. Epub 2014 Oct 28.


Impairment of autophagy in endothelial cells prevents shear-stress-induced increases in nitric oxide bioavailability.

Bharath LP, Mueller R, Li Y, Ruan T, Kunz D, Goodrich R, Mills T, Deeter L, Sargsyan A, Anandh Babu PV, Graham TE, Symons JD.

Can J Physiol Pharmacol. 2014 Jul;92(7):605-12. doi: 10.1139/cjpp-2014-0017. Epub 2014 Jun 18.


Opportunity "nox": a novel approach to preventing endothelial dysfunction in the context of insulin resistance.

Symons JD.

Diabetes. 2013 Jun;62(6):1818-20. doi: 10.2337/db13-0255. No abstract available.


A low-carbohydrate/high-fat diet reduces blood pressure in spontaneously hypertensive rats without deleterious changes in insulin resistance.

Bosse JD, Lin HY, Sloan C, Zhang QJ, Abel ED, Pereira TJ, Dolinsky VW, Symons JD, Jalili T.

Am J Physiol Heart Circ Physiol. 2013 Jun 15;304(12):H1733-42. doi: 10.1152/ajpheart.00631.2012. Epub 2013 Apr 19.


Lipotoxicity contributes to endothelial dysfunction: a focus on the contribution from ceramide.

Symons JD, Abel ED.

Rev Endocr Metab Disord. 2013 Mar;14(1):59-68. doi: 10.1007/s11154-012-9235-3. Review.


Mechanisms of lipotoxicity in the cardiovascular system.

Wende AR, Symons JD, Abel ED.

Curr Hypertens Rep. 2012 Dec;14(6):517-31. doi: 10.1007/s11906-012-0307-2. Review.

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