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Items: 1 to 20 of 31

1.

Metal ion coordination delays amyloid-β peptide self-assembly by forming an aggregation-inert complex.

Wallin C, Jarvet J, Biverstål H, Wärmländer S, Danielsson J, Gräslund A, Abelein A.

J Biol Chem. 2020 Apr 2. pii: jbc.RA120.012738. doi: 10.1074/jbc.RA120.012738. [Epub ahead of print]

2.

Mercury and Alzheimer's Disease: Hg(II) Ions Display Specific Binding to the Amyloid-β Peptide and Hinder Its Fibrillization.

Wallin C, Friedemann M, Sholts SB, Noormägi A, Svantesson T, Jarvet J, Roos PM, Palumaa P, Gräslund A, Wärmländer SKTS.

Biomolecules. 2019 Dec 27;10(1). pii: E44. doi: 10.3390/biom10010044.

3.

Metal binding to the amyloid-β peptides in the presence of biomembranes: potential mechanisms of cell toxicity.

Wärmländer SKTS, Österlund N, Wallin C, Wu J, Luo J, Tiiman A, Jarvet J, Gräslund A.

J Biol Inorg Chem. 2019 Dec;24(8):1189-1196. doi: 10.1007/s00775-019-01723-9. Epub 2019 Sep 27. Review.

PMID:
31562546
4.

Effects of in vivo conditions on amyloid aggregation.

Owen MC, Gnutt D, Gao M, Wärmländer SKTS, Jarvet J, Gräslund A, Winter R, Ebbinghaus S, Strodel B.

Chem Soc Rev. 2019 Jul 15;48(14):3946-3996. doi: 10.1039/c8cs00034d. Review.

PMID:
31192324
5.

Amyloidogenic Nanoplaques in Blood Serum of Patients with Alzheimer's Disease Revealed by Time-Resolved Thioflavin T Fluorescence Intensity Fluctuation Analysis.

Tiiman A, Jelić V, Jarvet J, Järemo P, Bogdanović N, Rigler R, Terenius L, Gräslund A, Vukojević V.

J Alzheimers Dis. 2019;68(2):571-582. doi: 10.3233/JAD-181144.

6.

Copper ions induce dityrosine-linked dimers in human but not in murine islet amyloid polypeptide (IAPP/amylin).

Dong X, Svantesson T, Sholts SB, Wallin C, Jarvet J, Gräslund A, Wärmländer SKTS.

Biochem Biophys Res Commun. 2019 Mar 19;510(4):520-524. doi: 10.1016/j.bbrc.2019.01.120. Epub 2019 Feb 6.

PMID:
30737030
7.

The Neuronal Tau Protein Blocks in Vitro Fibrillation of the Amyloid-β (Aβ) Peptide at the Oligomeric Stage.

Wallin C, Hiruma Y, Wärmländer SKTS, Huvent I, Jarvet J, Abrahams JP, Gräslund A, Lippens G, Luo J.

J Am Chem Soc. 2018 Jul 5;140(26):8138-8146. doi: 10.1021/jacs.7b13623. Epub 2018 May 22.

PMID:
29708745
8.

Amyloid-β Peptide Interactions with Amphiphilic Surfactants: Electrostatic and Hydrophobic Effects.

Österlund N, Kulkarni YS, Misiaszek AD, Wallin C, Krüger DM, Liao Q, Mashayekhy Rad F, Jarvet J, Strodel B, Wärmländer SKTS, Ilag LL, Kamerlin SCL, Gräslund A.

ACS Chem Neurosci. 2018 Jul 18;9(7):1680-1692. doi: 10.1021/acschemneuro.8b00065. Epub 2018 May 4.

PMID:
29683649
9.

Shortfall of B3LYP in Reproducing NMR JCH Couplings in Some Isomeric Epoxy Structures with Strong Stereoelectronic Effects: A Benchmark Study on DFT Functionals.

Adamson J, Nazarski RB, Jarvet J, Pehk T, Aav R.

Chemphyschem. 2018 Mar 5;19(5):631-642. doi: 10.1002/cphc.201701125. Epub 2018 Jan 12.

PMID:
29168914
10.

Alzheimer's disease and cigarette smoke components: effects of nicotine, PAHs, and Cd(II), Cr(III), Pb(II), Pb(IV) ions on amyloid-β peptide aggregation.

Wallin C, Sholts SB, Österlund N, Luo J, Jarvet J, Roos PM, Ilag L, Gräslund A, Wärmländer SKTS.

Sci Rep. 2017 Oct 31;7(1):14423. doi: 10.1038/s41598-017-13759-5.

11.

Ionic Strength Modulation of the Free Energy Landscape of Aβ40 Peptide Fibril Formation.

Abelein A, Jarvet J, Barth A, Gräslund A, Danielsson J.

J Am Chem Soc. 2016 Jun 1;138(21):6893-902. doi: 10.1021/jacs.6b04511. Epub 2016 May 23.

PMID:
27171340
12.

Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer's disease.

Wallin C, Kulkarni YS, Abelein A, Jarvet J, Liao Q, Strodel B, Olsson L, Luo J, Abrahams JP, Sholts SB, Roos PM, Kamerlin SC, Gräslund A, Wärmländer SK.

J Trace Elem Med Biol. 2016 Dec;38:183-193. doi: 10.1016/j.jtemb.2016.03.009. Epub 2016 Mar 18.

PMID:
27085215
13.

Heterogeneity and Turnover of Intermediates during Amyloid-β (Aβ) Peptide Aggregation Studied by Fluorescence Correlation Spectroscopy.

Tiiman A, Jarvet J, Gräslund A, Vukojević V.

Biochemistry. 2015 Dec 15;54(49):7203-11. doi: 10.1021/acs.biochem.5b00976. Epub 2015 Dec 3.

PMID:
26574169
14.

The hairpin conformation of the amyloid β peptide is an important structural motif along the aggregation pathway.

Abelein A, Abrahams JP, Danielsson J, Gräslund A, Jarvet J, Luo J, Tiiman A, Wärmländer SK.

J Biol Inorg Chem. 2014 Jun;19(4-5):623-34. doi: 10.1007/s00775-014-1131-8. Epub 2014 Apr 16. Review.

PMID:
24737040
15.

The role of pro-inflammatory S100A9 in Alzheimer's disease amyloid-neuroinflammatory cascade.

Wang C, Klechikov AG, Gharibyan AL, Wärmländer SK, Jarvet J, Zhao L, Jia X, Narayana VK, Shankar SK, Olofsson A, Brännström T, Mu Y, Gräslund A, Morozova-Roche LA.

Acta Neuropathol. 2014 Apr;127(4):507-22. doi: 10.1007/s00401-013-1208-4. Epub 2013 Nov 16. Erratum in: Acta Neuropathol. 2014 Sep;128(3):461.

16.

An NMR and MD modeling insight into nucleation of 1,2-alkanediols: selective crystallization of lipase-catalytically resolved enantiomers from the reaction mixtures.

Parve O, Reile I, Parve J, Kasvandik S, Kudrjašova M, Tamp S, Metsala A, Villo L, Pehk T, Jarvet J, Vares L.

J Org Chem. 2013 Dec 20;78(24):12795-801. doi: 10.1021/jo402189e. Epub 2013 Nov 14.

PMID:
24228810
17.

The transcriptional repressor domain of Gli3 is intrinsically disordered.

Tsanev R, Vanatalu K, Jarvet J, Tanner R, Laur K, Tiigimägi P, Kragelund BB, Østerlund T, Kogerman P.

PLoS One. 2013 Oct 17;8(10):e76972. doi: 10.1371/journal.pone.0076972. eCollection 2013.

18.

Specific binding of a β-cyclodextrin dimer to the amyloid β peptide modulates the peptide aggregation process.

Wahlström A, Cukalevski R, Danielsson J, Jarvet J, Onagi H, Rebek J Jr, Linse S, Gräslund A.

Biochemistry. 2012 May 29;51(21):4280-9. doi: 10.1021/bi300341j. Epub 2012 May 17.

PMID:
22554145
19.

Secondary structure conversions of Alzheimer's Abeta(1-40) peptide induced by membrane-mimicking detergents.

Wahlström A, Hugonin L, Perálvarez-Marín A, Jarvet J, Gräslund A.

FEBS J. 2008 Oct;275(20):5117-28. doi: 10.1111/j.1742-4658.2008.06643.x. Epub 2008 Sep 10.

20.

Making a single-chain four-helix bundle for redox chemistry studies.

Westerlund K, Moran SD, Privett HK, Hay S, Jarvet J, Gibney BR, Tommos C.

Protein Eng Des Sel. 2008 Nov;21(11):645-52. doi: 10.1093/protein/gzn043. Epub 2008 Aug 28.

PMID:
18755707

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