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Items: 16


Modeling the Effect of Hypoxia and DNA Repair Inhibition on Cell Survival After Photon Irradiation.

Liew H, Klein C, Zenke FT, Abdollahi A, Debus J, Dokic I, Mairani A.

Int J Mol Sci. 2019 Nov 30;20(23). pii: E6054. doi: 10.3390/ijms20236054.


Development and Validation of Single Field Multi-Ion Particle Therapy Treatments.

Kopp B, Mein S, Dokic I, Harrabi S, Böhlen TT, Haberer T, Debus J, Abdollahi A, Mairani A.

Int J Radiat Oncol Biol Phys. 2020 Jan 1;106(1):194-205. doi: 10.1016/j.ijrobp.2019.10.008. Epub 2019 Oct 11.


Biophysical modeling and experimental validation of relative biological effectiveness (RBE) for 4He ion beam therapy.

Mein S, Dokic I, Klein C, Tessonnier T, Böhlen TT, Magro G, Bauer J, Ferrari A, Parodi K, Haberer T, Debus J, Abdollahi A, Mairani A.

Radiat Oncol. 2019 Jul 11;14(1):123. doi: 10.1186/s13014-019-1295-z.


Carbon irradiation overcomes glioma radioresistance by eradicating stem cells and forming an antiangiogenic and immunopermissive niche.

Chiblak S, Tang Z, Lemke D, Knoll M, Dokic I, Warta R, Moustafa M, Mier W, Brons S, Rapp C, Muschal S, Seidel P, Bendszus M, Adeberg S, Wiestler OD, Haberkorn U, Debus J, Herold-Mende C, Wick W, Abdollahi A.

JCI Insight. 2019 Jan 24;4(2). pii: 123837. doi: 10.1172/jci.insight.123837. [Epub ahead of print]


Pastoral care and religious support as a part of treatment of religious patient with the severe form of osteoarthritis.

Đurović A, Sovilj S, Đokić I, Brdareski Z, Vukomanović A, Ilić N, Milavić-Vujković M.

Vojnosanit Pregl. 2017 Jan;74(1):69-77. doi: 10.2298/VSP1508025059D.


Overcoming hypoxia-induced tumor radioresistance in non-small cell lung cancer by targeting DNA-dependent protein kinase in combination with carbon ion irradiation.

Klein C, Dokic I, Mairani A, Mein S, Brons S, Häring P, Haberer T, Jäkel O, Zimmermann A, Zenke F, Blaukat A, Debus J, Abdollahi A.

Radiat Oncol. 2017 Dec 29;12(1):208. doi: 10.1186/s13014-017-0939-0.


Optimization of Monte Carlo particle transport parameters and validation of a novel high throughput experimental setup to measure the biological effects of particle beams.

Patel D, Bronk L, Guan F, Peeler CR, Brons S, Dokic I, Abdollahi A, Rittmüller C, Jäkel O, Grosshans D, Mohan R, Titt U.

Med Phys. 2017 Nov;44(11):6061-6073. doi: 10.1002/mp.12568. Epub 2017 Oct 9.


Comparative analysis of the effects of a sphingosine kinase inhibitor to temozolomide and radiation treatment on glioblastoma cell lines.

Oancea-Castillo LR, Klein C, Abdollahi A, Weber KJ, Régnier-Vigouroux A, Dokic I.

Cancer Biol Ther. 2017 Jun 3;18(6):400-406. doi: 10.1080/15384047.2017.1323583. Epub 2017 May 11.


Deciphering the Acute Cellular Phosphoproteome Response to Irradiation with X-rays, Protons and Carbon Ions.

Winter M, Dokic I, Schlegel J, Warnken U, Debus J, Abdollahi A, Schnölzer M.

Mol Cell Proteomics. 2017 May;16(5):855-872. doi: 10.1074/mcp.M116.066597. Epub 2017 Mar 16.


Next generation multi-scale biophysical characterization of high precision cancer particle radiotherapy using clinical proton, helium-, carbon- and oxygen ion beams.

Dokic I, Mairani A, Niklas M, Zimmermann F, Chaudhri N, Krunic D, Tessonnier T, Ferrari A, Parodi K, Jäkel O, Debus J, Haberer T, Abdollahi A.

Oncotarget. 2016 Aug 30;7(35):56676-56689. doi: 10.18632/oncotarget.10996.


Correlation of Particle Traversals with Clonogenic Survival Using Cell-Fluorescent Ion Track Hybrid Detector.

Dokic I, Niklas M, Zimmermann F, Mairani A, Seidel P, Krunic D, Jäkel O, Debus J, Greilich S, Abdollahi A.

Front Oncol. 2015 Dec 7;5:275. doi: 10.3389/fonc.2015.00275. eCollection 2015.


High resistance to X-rays and therapeutic carbon ions in glioblastoma cells bearing dysfunctional ATM associates with intrinsic chromosomal instability.

Dokic I, Mairani A, Brons S, Schoell B, Jauch A, Krunic D, Debus J, Régnier-Vigouroux A, Weber KJ.

Int J Radiat Biol. 2015 Feb;91(2):157-65. doi: 10.3109/09553002.2014.937511. Epub 2014 Sep 8.


Modelling of cell killing due to sparsely ionizing radiation in normoxic and hypoxic conditions and an extension to high LET radiation.

Mairani A, Böhlen TT, Dokic I, Cabal G, Brons S, Haberer T.

Int J Radiat Biol. 2013 Oct;89(10):782-93. doi: 10.3109/09553002.2013.800247. Epub 2013 Jun 26.


Glutathione peroxidase 1 activity dictates the sensitivity of glioblastoma cells to oxidative stress.

Dokic I, Hartmann C, Herold-Mende C, Régnier-Vigouroux A.

Glia. 2012 Nov;60(11):1785-800. doi: 10.1002/glia.22397. Epub 2012 Aug 1.


Sphingolipid rheostat alterations related to transformation can be exploited for specific induction of lysosomal cell death in murine and human glioma.

Mora R, Dokic I, Kees T, Hüber CM, Keitel D, Geibig R, Brügge B, Zentgraf H, Brady NR, Régnier-Vigouroux A.

Glia. 2010 Aug 15;58(11):1364-83. doi: 10.1002/glia.21013.


TNF-alpha- and TRAIL-resistant glioma cells undergo autophagy-dependent cell death induced by activated microglia.

Mora R, Abschuetz A, Kees T, Dokic I, Joschko N, Kleber S, Geibig R, Mosconi E, Zentgraf H, Martin-Villalba A, Régnier-Vigouroux A.

Glia. 2009 Apr 1;57(5):561-81. doi: 10.1002/glia.20785.


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