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Items: 1 to 20 of 67

1.

Solid-Phase Synthesis of Phosphorothioate/Phosphonothioate and Phosphoramidate/Phosphonamidate Oligonucleotides.

Kostov O, Liboska R, Páv O, Novák P, Rosenberg I.

Molecules. 2019 May 15;24(10). pii: E1872. doi: 10.3390/molecules24101872.

2.

Nucleoside-O-Methyl-(H)-Phosphinates: Novel Monomers for the Synthesis of Methylphosphonate Oligonucleotides Using H-Phosphonate Chemistry.

Kostov O, Páv O, Rosenberg I.

Curr Protoc Nucleic Acid Chem. 2017 Sep 18;70:4.76.1-4.76.22. doi: 10.1002/cpnc.35.

PMID:
28921496
3.

Tuning the hybridization properties of modified oligonucleotides: from flexible to conformationally constrained phosphonate internucleotide linkages.

Páv O, Barvík I, Liboska R, Petrová M, Šimák O, Rosenbergová Š, Novák P, Buděšínský M, Rosenberg I.

Org Biomol Chem. 2017 Jan 18;15(3):701-707. doi: 10.1039/c6ob02571d.

PMID:
27995239
4.

Synthesis of 4'-Methoxy 2'-Deoxynucleoside Phosphoramidites for Incorporation into Oligonucleotides.

Petrová M, Rosenberg I.

Curr Protoc Nucleic Acid Chem. 2016 Sep 1;66:1.38.1-1.38.27. doi: 10.1002/cpnc.15.

PMID:
27584701
5.

4-Toluenesulfonyloxymethyl-(H)-phosphinate: A Reagent for the Introduction of O- and S-Methyl-(H)-phosphinate Moieties.

Kostov O, Páv O, Buděšínský M, Liboska R, Šimák O, Petrová M, Novák P, Rosenberg I.

Org Lett. 2016 Jun 3;18(11):2704-7. doi: 10.1021/acs.orglett.6b01167. Epub 2016 May 13.

PMID:
27177076
6.

Dr Jekyll and Mr Hyde: a strange case of 5-ethynyl-2'-deoxyuridine and 5-ethynyl-2'-deoxycytidine.

Ligasová A, Liboska R, Friedecký D, Mičová K, Adam T, Oždian T, Rosenberg I, Koberna K.

Open Biol. 2016 Jan;6(1):150172. doi: 10.1098/rsob.150172.

7.

The Fingerprint of Anti-Bromodeoxyuridine Antibodies and Its Use for the Assessment of Their Affinity to 5-Bromo-2'-Deoxyuridine in Cellular DNA under Various Conditions.

Ligasová A, Liboska R, Rosenberg I, Koberna K.

PLoS One. 2015 Jul 10;10(7):e0132393. doi: 10.1371/journal.pone.0132393. eCollection 2015.

8.

Straightforward Synthesis of Purine 4'-Alkoxy-2'-deoxynucleosides: First Report of Mixed Purine-Pyrimidine 4'-Alkoxyoligodeoxynucleotides as New RNA Mimics.

Petrová M, Páv O, Buděšínský M, Zborníková E, Novák P, Rosenbergová Š, Pačes O, Liboska R, Dvořáková I, Šimák O, Rosenberg I.

Org Lett. 2015 Jul 17;17(14):3426-9. doi: 10.1021/acs.orglett.5b01430. Epub 2015 Jul 2.

PMID:
26133076
9.

N-Branched acyclic nucleoside phosphonates as monomers for the synthesis of modified oligonucleotides.

Hocková D, Rosenbergová Š, Ménová P, Páv O, Pohl R, Novák P, Rosenberg I.

Org Biomol Chem. 2015 Apr 21;13(15):4449-58. doi: 10.1039/c4ob02265c.

PMID:
25766752
10.

A comparison of the dose distributions from three proton treatment planning systems in the planning of meningioma patients with single-field uniform dose pencil beam scanning.

Doolan PJ, Alshaikhi J, Rosenberg I, Ainsley CG, Gibson A, D'Souza D, Bentefour el H, Royle G.

J Appl Clin Med Phys. 2015 Jan 8;16(1):4996. doi: 10.1120/jacmp.v16i1.4996.

11.

Synthesis of locked cyclohexene and cyclohexane nucleic acids (LCeNA and LCNA) with modified adenosine units.

Šála M, Dejmek M, Procházková E, Hřebabecký H, Rybáček J, Dračínský M, Novák P, Rosenbergová Š, Fukal J, Sychrovský V, Rosenberg I, Nencka R.

Org Biomol Chem. 2015 Mar 7;13(9):2703-15. doi: 10.1039/c4ob02193b.

PMID:
25594585
12.

In vivo dosimetry for total body irradiation: five-year results and technique comparison.

Patel RP, Warry AJ, Eaton DJ, Collis CH, Rosenberg I.

J Appl Clin Med Phys. 2014 Jul 8;15(4):4939. doi: 10.1120/jacmp.v15i4.4939.

13.

Assessment of the dosimetric accuracies of CATPhan 504 and CIRS 062 using kV-CBCT for performing direct calculations.

Annkah JK, Rosenberg I, Hindocha N, Moinuddin SA, Ricketts K, Adeyemi A, Royle G.

J Med Phys. 2014 Jul;39(3):133-41. doi: 10.4103/0971-6203.139001.

14.

Conformationally constrained nucleoside phosphonic acids--potent inhibitors of human mitochondrial and cytosolic 5'(3')-nucleotidases.

Šimák O, Pachl P, Fábry M, Buděšínský M, Jandušík T, Hnízda A, Skleničková R, Petrová M, Veverka V, Řezáčová P, Brynda J, Rosenberg I.

Org Biomol Chem. 2014 Oct 28;12(40):7971-82. doi: 10.1039/c4ob01332h. Epub 2014 Sep 1.

PMID:
25178098
15.

Theoretical and experimental study of charge transfer through DNA: impact of mercury mediated T-Hg-T base pair.

Kratochvílová I, Golan M, Vala M, Špérová M, Weiter M, Páv O, Šebera J, Rosenberg I, Sychrovský V, Tanaka Y, Bickelhaupt FM.

J Phys Chem B. 2014 May 22;118(20):5374-81. doi: 10.1021/jp501986a. Epub 2014 May 7.

PMID:
24780102
16.

Imaging Cerenkov emission as a quality assurance tool in electron radiotherapy.

Helo Y, Rosenberg I, D'Souza D, Macdonald L, Speller R, Royle G, Gibson A.

Phys Med Biol. 2014 Apr 21;59(8):1963-78. doi: 10.1088/0031-9155/59/8/1963. Epub 2014 Apr 2.

PMID:
24694567
17.

Structures of human cytosolic and mitochondrial nucleotidases: implications for structure-based design of selective inhibitors.

Pachl P, Fábry M, Rosenberg I, Simák O, Rezáčová P, Brynda J.

Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):461-70. doi: 10.1107/S1399004713030502. Epub 2014 Jan 29.

PMID:
24531480
18.

5'-O-Methylphosphonate nucleic acids--new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes.

Šipova H, Špringer T, Rejman D, Šimak O, Petrová M, Novák P, Rosenbergová Š, Páv O, Liboska R, Barvík I, Štěpanek J, Rosenberg I, Homola J.

Nucleic Acids Res. 2014 Apr;42(8):5378-89. doi: 10.1093/nar/gku125. Epub 2014 Feb 12.

19.

Inhibition of human thymidine phosphorylase by conformationally constrained pyrimidine nucleoside phosphonic acids and their "open-structure" isosteres.

Košiová I, Šimák O, Panova N, Buděšínský M, Petrová M, Rejman D, Liboska R, Páv O, Rosenberg I.

Eur J Med Chem. 2014 Mar 3;74:145-68. doi: 10.1016/j.ejmech.2013.12.026. Epub 2014 Jan 3.

PMID:
24462848
20.

Charge transfer through DNA/DNA duplexes and DNA/RNA hybrids: complex theoretical and experimental studies.

Kratochvílová I, Vala M, Weiter M, Špérová M, Schneider B, Páv O, Šebera J, Rosenberg I, Sychrovský V.

Biophys Chem. 2013 Oct-Nov;180-181:127-34. doi: 10.1016/j.bpc.2013.07.009. Epub 2013 Jul 31.

PMID:
23968861

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