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Items: 1 to 20 of 144


The potential use of grape phytochemicals for preventing the development of intestine-related and subsequent inflammatory diseases.

Santa K, Kumazawa Y, Nagaoka I.

Endocr Metab Immune Disord Drug Targets. 2019 May 28. doi: 10.2174/1871530319666190529105226. [Epub ahead of print]


Effect of aging on the tendon structure and tendon-associated gene expression in mouse foot flexor tendon.

Sugiyama Y, Naito K, Goto K, Kojima Y, Furuhata A, Igarashi M, Nagaoka I, Kaneko K.

Biomed Rep. 2019 Apr;10(4):238-244. doi: 10.3892/br.2019.1200. Epub 2019 Mar 13.


Chondroprotective action of glucosamine, a chitosan monomer, on the joint health of athletes.

Nagaoka I, Tsuruta A, Yoshimura M.

Int J Biol Macromol. 2019 Jul 1;132:795-800. doi: 10.1016/j.ijbiomac.2019.03.234. Epub 2019 Mar 30. Review.


Low Endotoxin Recovery-Masking of Naturally Occurring Endotoxin.

Reich J, Weyer FA, Tamura H, Nagaoka I, Motschmann H.

Int J Mol Sci. 2019 Feb 15;20(4). pii: E838. doi: 10.3390/ijms20040838.


Impact of primary tumor location as a predictive factor in patients suffering from colorectal cancer treated with cytotoxic anticancer agents based on the collagen gel droplet-embedded drug sensitivity test.

Ochiai T, Nishimura K, Watanabe T, Kitajima M, Nakatani A, Nagayasu K, Sakuyama N, Sato T, Kishine K, Abe Y, Nagaoka I.

Oncol Lett. 2019 Feb;17(2):1842-1850. doi: 10.3892/ol.2018.9805. Epub 2018 Dec 6.


MrgX2‑mediated internalization of LL‑37 and degranulation of human LAD2 mast cells.

Murakami T, Suzuki K, Niyonsaba F, Tada H, Reich J, Tamura H, Nagaoka I.

Mol Med Rep. 2018 Dec;18(6):4951-4959. doi: 10.3892/mmr.2018.9532. Epub 2018 Oct 2.


Protection of the endothelial glycocalyx by antithrombin in an endotoxin-induced rat model of sepsis.

Iba T, Levy JH, Hirota T, Hiki M, Sato K, Murakami T, Nagaoka I.

Thromb Res. 2018 Nov;171:1-6. doi: 10.1016/j.thromres.2018.09.042. Epub 2018 Sep 6.


Evaluation of the effect of the administration of a glucosamine‑containing supplement on biomarkers for cartilage metabolism in soccer players: A randomized double‑blind placebo‑controlled study.

Tsuruta A, Horiike T, Yoshimura M, Nagaoka I.

Mol Med Rep. 2018 Oct;18(4):3941-3948. doi: 10.3892/mmr.2018.9396. Epub 2018 Aug 17.


Investigation of the kinetics and mechanism of low endotoxin recovery in a matrix for biopharmaceutical drug products.

Reich J, Tamura H, Nagaoka I, Motschmann H.

Biologicals. 2018 May;53:1-9. doi: 10.1016/j.biologicals.2018.04.001. Epub 2018 Apr 21.


JAK2/STAT3 pathway as a therapeutic target in ovarian cancers.

Yoshikawa T, Miyamoto M, Aoyama T, Soyama H, Goto T, Hirata J, Suzuki A, Nagaoka I, Tsuda H, Furuya K, Takano M.

Oncol Lett. 2018 Apr;15(4):5772-5780. doi: 10.3892/ol.2018.8028. Epub 2018 Feb 12.


Effect of intermittent administration of teriparatide on the mechanical and histological changes in bone grafted with β-tricalcium phosphate using a rabbit bone defect model.

Komatsu J, Nagura N, Iwase H, Igarashi M, Ohbayashi O, Nagaoka I, Kaneko K.

Exp Ther Med. 2018 Jan;15(1):19-30. doi: 10.3892/etm.2017.5424. Epub 2017 Nov 1.


Protective effect of a newly developed fucose-deficient recombinant antithrombin against histone-induced endothelial damage.

Iba T, Hirota T, Sato K, Nagaoka I.

Int J Hematol. 2018 May;107(5):528-534. doi: 10.1007/s12185-018-2402-x. Epub 2018 Jan 20.


Impact of the individualization of the first-line chemotherapy for advanced colorectal cancer based on collagen gel droplet-embedded drug sensitivity test.

Ochiai T, Nishimura K, Watanabe T, Kitajima M, Nakatani A, Nagayasu K, Naito S, Sato T, Kishine K, Abe Y, Hara C, Yamada S, Mashiko S, Nagaoka I.

Oncol Lett. 2017 Nov;14(5):6045-6052. doi: 10.3892/ol.2017.6960. Epub 2017 Sep 15.


Evaluation of the efficacy of Ajuga decumbens extract supplement in individuals with knee discomfort associated with physical activity: A randomized, double-blind, placebo-controlled study.

Sawada Y, Sugimoto A, Hananouchi T, Sato N, Nagaoka I.

Exp Ther Med. 2017 Nov;14(5):4561-4571. doi: 10.3892/etm.2017.5064. Epub 2017 Aug 29.


Evaluation of the chondroprotective action of N-acetylglucosamine in a rat experimental osteoarthritis model.

Kubomura D, Ueno T, Yamada M, Nagaoka I.

Exp Ther Med. 2017 Oct;14(4):3137-3144. doi: 10.3892/etm.2017.4849. Epub 2017 Jul 28.


Anti‑inflammatory actions of gabapentin and pregabalin on the substance P‑induced mitogen‑activated protein kinase activation in U373 MG human glioblastoma astrocytoma cells.

Yamaguchi K, Kumakura S, Someya A, Iseki M, Inada E, Nagaoka I.

Mol Med Rep. 2017 Nov;16(5):6109-6115. doi: 10.3892/mmr.2017.7368. Epub 2017 Aug 28.


Psoas muscle volume as a predictor of peripheral neurotoxicity induced by primary chemotherapy in ovarian cancers.

Yoshikawa T, Takano M, Miyamoto M, Yajima I, Shimizu Y, Aizawa Y, Suguchi Y, Moriiwa M, Aoyama T, Soyama H, Goto T, Hirata J, Suzuki A, Sasa H, Nagaoka I, Tsuda H, Furuya K.

Cancer Chemother Pharmacol. 2017 Sep;80(3):555-561. doi: 10.1007/s00280-017-3395-5. Epub 2017 Jul 19.


Evaluation of the effect of salmon nasal proteoglycan on biomarkers for cartilage metabolism in individuals with knee joint discomfort: A randomized double-blind placebo-controlled clinical study.

Tomonaga A, Takahashi T, Tanaka YT, Tsuboi M, Ito K, Nagaoka I.

Exp Ther Med. 2017 Jul;14(1):115-126. doi: 10.3892/etm.2017.4454. Epub 2017 May 11.


The Comparison of the Protective Effects of α- and β-Antithrombin against Vascular Endothelial Cell Damage Induced by Histone in Vitro.

Iba T, Sasaki T, Ohshima K, Sato K, Nagaoka I, Thachil J.

TH Open. 2017 Jun 28;1(1):e3-e10. doi: 10.1055/s-0037-1603926. eCollection 2017 Jun.


Evaluation of the effect of recombinant thrombomodulin on a lipopolysaccharide-induced murine sepsis model.

Takehara K, Murakami T, Kuwahara-Arai K, Iba T, Nagaoka I, Sakamoto K.

Exp Ther Med. 2017 Jun;13(6):2969-2974. doi: 10.3892/etm.2017.4308. Epub 2017 Apr 5.

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