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Items: 1 to 20 of 55

1.

Determination of intestinal permeability using in situ perfusion model in rats: challenges and advantages to BCS classification applied to digoxin.

Caldeira TG, Ruiz-Picazo A, Lozoya-Agullo I, Saúde-Guimarães DA, González-Álvarez M, de Souza J, González-Álvarez I, Bermejo M.

Int J Pharm. 2018 Sep 12. pii: S0378-5173(18)30673-2. doi: 10.1016/j.ijpharm.2018.09.022. [Epub ahead of print]

PMID:
30218825
2.

Preclinical models for colonic absorption, application to controlled release formulation development.

Lozoya-Agullo I, González-Álvarez I, Merino-Sanjuán M, Bermejo M, González-Álvarez M.

Eur J Pharm Biopharm. 2018 Sep;130:247-259. doi: 10.1016/j.ejpb.2018.07.008. Epub 2018 Jul 6. Review.

PMID:
30064699
3.

Biopharmaceutical optimization in neglected diseases for paediatric patients by applying the provisional paediatric biopharmaceutical classification system.

Del Moral Sanchez JM, Gonzalez-Alvarez I, Cerda-Revert A, Gonzalez-Alvarez M, Navarro-Ruiz A, Amidon GL, Bermejo M.

Br J Clin Pharmacol. 2018 Oct;84(10):2231-2241. doi: 10.1111/bcp.13650. Epub 2018 Jul 17.

PMID:
29846973
4.

Smart gated magnetic silica mesoporous particles for targeted colon drug delivery: New approaches for inflammatory bowel diseases treatment.

Teruel AH, Pérez-Esteve É, González-Álvarez I, González-Álvarez M, Costero AM, Ferri D, Parra M, Gaviña P, Merino V, Martínez-Mañez R, Sancenón F.

J Control Release. 2018 Jul 10;281:58-69. doi: 10.1016/j.jconrel.2018.05.007. Epub 2018 May 10.

PMID:
29753956
5.

In Vitro Dissolution as a Tool for Formulation Selection: Telmisartan Two-Step IVIVC.

Ruiz Picazo A, Martinez-Martinez MT, Colón-Useche S, Iriarte R, Sánchez-Dengra B, González-Álvarez M, García-Arieta A, González-Álvarez I, Bermejo M.

Mol Pharm. 2018 Jun 4;15(6):2307-2315. doi: 10.1021/acs.molpharmaceut.8b00153. Epub 2018 May 17.

PMID:
29746133
6.

Appropriate use of medical imaging in two Spanish public hospitals: a cross-sectional analysis.

Vilar-Palop J, Hernandez-Aguado I, Pastor-Valero M, Vilar J, González-Alvarez I, Lumbreras B.

BMJ Open. 2018 Mar 16;8(3):e019535. doi: 10.1136/bmjopen-2017-019535.

7.

Ionic Hydrogel Based on Chitosan Cross-Linked with 6-Phosphogluconic Trisodium Salt as a Drug Delivery System.

Martínez-Martínez M, Rodríguez-Berna G, Gonzalez-Alvarez I, Hernández MJ, Corma A, Bermejo M, Merino V, Gonzalez-Alvarez M.

Biomacromolecules. 2018 Apr 9;19(4):1294-1304. doi: 10.1021/acs.biomac.8b00108. Epub 2018 Mar 22.

PMID:
29537830
8.

Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in vivo approach.

Hens B, Bermejo M, Tsume Y, Gonzalez-Alvarez I, Ruan H, Matsui K, Amidon GE, Cavanagh KL, Kuminek G, Benninghoff G, Fan J, Rodríguez-Hornedo N, Amidon GL.

Eur J Pharm Sci. 2018 Mar 30;115:258-269. doi: 10.1016/j.ejps.2018.01.039.

PMID:
29378253
9.

Closed-Loop Doluisio (Colon, Small Intestine) and Single-Pass Intestinal Perfusion (Colon, Jejunum) in Rat-Biophysical Model and Predictions Based on Caco-2.

Lozoya-Agullo I, Gonzalez-Alvarez I, Zur M, Fine-Shamir N, Cohen Y, Markovic M, Garrigues TM, Dahan A, Gonzalez-Alvarez M, Merino-Sanjuán M, Bermejo M, Avdeef A.

Pharm Res. 2017 Dec 29;35(1):2. doi: 10.1007/s11095-017-2331-z.

PMID:
29288412
10.

PLGA nanoparticles are effective to control the colonic release and absorption on ibuprofen.

Lozoya-Agullo I, Araújo F, González-Álvarez I, Merino-Sanjuán M, González-Álvarez M, Bermejo M, Sarmento B.

Eur J Pharm Sci. 2018 Mar 30;115:119-125. doi: 10.1016/j.ejps.2017.12.009. Epub 2017 Dec 14.

PMID:
29248559
11.

Gated Mesoporous Silica Nanocarriers for a "Two-Step" Targeted System to Colonic Tissue.

González-Alvarez M, Coll C, Gonzalez-Alvarez I, Giménez C, Aznar E, Martínez-Bisbal MC, Lozoya-Agulló I, Bermejo M, Martínez-Máñez R, Sancenón F.

Mol Pharm. 2017 Dec 4;14(12):4442-4453. doi: 10.1021/acs.molpharmaceut.7b00565. Epub 2017 Nov 9.

PMID:
29064714
12.

Comparison of segmental-dependent permeability in human and in situ perfusion model in rat.

Ruiz-Picazo A, Lozoya-Agullo I, Ortiz-Azcarate M, Merino-Sanjuán M, González-Álvarez M, González-Álvarez I, Bermejo M.

Eur J Pharm Sci. 2017 Sep 30;107:191-196. doi: 10.1016/j.ejps.2017.06.033. Epub 2017 Jul 4.

PMID:
28687530
13.

Avoiding fears and promoting shared decision-making: How should physicians inform patients about radiation exposure from imaging tests?

Lumbreras B, Vilar J, González-Álvarez I, Guilabert M, Pastor-Valero M, Parker LA, Vilar-Palop J, Hernández-Aguado I.

PLoS One. 2017 Jul 7;12(7):e0180592. doi: 10.1371/journal.pone.0180592. eCollection 2017.

14.

Investigating drug absorption from the colon: Single-pass vs. Doluisio approaches to in-situ rat large-intestinal perfusion.

Lozoya-Agullo I, Zur M, Fine-Shamir N, Markovic M, Cohen Y, Porat D, González-Álvarez I, González-Álvarez M, Merino-Sanjuán M, Bermejo M, Dahan A.

Int J Pharm. 2017 Jul 15;527(1-2):135-141. doi: 10.1016/j.ijpharm.2017.05.018. Epub 2017 May 10.

PMID:
28501438
15.

Usefulness of Caco-2/HT29-MTX and Caco-2/HT29-MTX/Raji B Coculture Models To Predict Intestinal and Colonic Permeability Compared to Caco-2 Monoculture.

Lozoya-Agullo I, Araújo F, González-Álvarez I, Merino-Sanjuán M, González-Álvarez M, Bermejo M, Sarmento B.

Mol Pharm. 2017 Apr 3;14(4):1264-1270. doi: 10.1021/acs.molpharmaceut.6b01165. Epub 2017 Mar 10.

PMID:
28263609
16.

Evaluation of the intestinal permeability of rosemary (Rosmarinus officinalis L.) extract polyphenols and terpenoids in Caco-2 cell monolayers.

Pérez-Sánchez A, Borrás-Linares I, Barrajón-Catalán E, Arráez-Román D, González-Álvarez I, Ibáñez E, Segura-Carretero A, Bermejo M, Micol V.

PLoS One. 2017 Feb 24;12(2):e0172063. doi: 10.1371/journal.pone.0172063. eCollection 2017.

17.

Updated effective doses in radiology.

Vilar-Palop J, Vilar J, Hernández-Aguado I, González-Álvarez I, Lumbreras B.

J Radiol Prot. 2016 Dec;36(4):975-990. Epub 2016 Nov 28. Review.

PMID:
27893456
18.

Population pharmacokinetic model of lithium and drug compliance assessment.

Pérez-Castelló I, Mangas-Sanjuan V, González-García I, Gonzalez-Alvarez I, Bermejo M, Marco-Garbayo JL, Trocóniz IF.

Eur Neuropsychopharmacol. 2016 Dec;26(12):1868-1876. doi: 10.1016/j.euroneuro.2016.11.005. Epub 2016 Nov 16.

PMID:
27865605
19.

Segmental-dependent permeability throughout the small intestine following oral drug administration: Single-pass vs. Doluisio approach to in-situ rat perfusion.

Lozoya-Agullo I, Zur M, Beig A, Fine N, Cohen Y, González-Álvarez M, Merino-Sanjuán M, González-Álvarez I, Bermejo M, Dahan A.

Int J Pharm. 2016 Dec 30;515(1-2):201-208. doi: 10.1016/j.ijpharm.2016.09.061. Epub 2016 Sep 22.

PMID:
27667756
20.

Assessment of the Regulatory Methods for the Comparison of Highly Variable Dissolution Profiles.

Mangas-Sanjuan V, Colon-Useche S, Gonzalez-Alvarez I, Bermejo M, Garcia-Arieta A.

AAPS J. 2016 Nov;18(6):1550-1561. Epub 2016 Aug 29.

PMID:
27571779

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