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Items: 1 to 20 of 58

1.

Covalently crosslinked organophosphorous derivatives-chitosan hydrogel as a drug delivery system for oral administration of camptothecin.

Martínez-Martínez M, Rodríguez-Berna G, Bermejo M, Gonzalez-Alvarez I, Gonzalez-Alvarez M, Merino V.

Eur J Pharm Biopharm. 2019 Mar;136:174-183. doi: 10.1016/j.ejpb.2019.01.009. Epub 2019 Jan 14.

PMID:
30654016
2.

Ion-pair approach coupled with nanoparticle formation to increase bioavailability of a low permeability charged drug.

Lozoya-Agullo I, Planelles M, Merino-Sanjuán M, Bermejo M, Sarmento B, González-Álvarez I, González-Álvarez M.

Int J Pharm. 2019 Feb 25;557:36-42. doi: 10.1016/j.ijpharm.2018.12.038. Epub 2018 Dec 20.

PMID:
30578978
3.

Long-Circulating Hyaluronan-Based Nanohydrogels as Carriers of Hydrophobic Drugs.

Di Meo C, Martínez-Martínez M, Coviello T, Bermejo M, Merino V, Gonzalez-Alvarez I, Gonzalez-Alvarez M, Matricardi P.

Pharmaceutics. 2018 Nov 3;10(4). pii: E213. doi: 10.3390/pharmaceutics10040213.

4.

Determination of intestinal permeability using in situ perfusion model in rats: Challenges and advantages to BCS classification applied to digoxin.

Caldeira TG, Ruiz-Picazo A, Lozoya-Agullo I, Saúde-Guimarães DA, González-Álvarez M, de Souza J, González-Álvarez I, Bermejo M.

Int J Pharm. 2018 Nov 15;551(1-2):148-157. doi: 10.1016/j.ijpharm.2018.09.022. Epub 2018 Sep 13.

PMID:
30218825
5.

Preclinical models for colonic absorption, application to controlled release formulation development.

Lozoya-Agullo I, González-Álvarez I, Merino-Sanjuán M, Bermejo M, González-Álvarez M.

Eur J Pharm Biopharm. 2018 Sep;130:247-259. doi: 10.1016/j.ejpb.2018.07.008. Epub 2018 Jul 6. Review.

PMID:
30064699
6.

Biopharmaceutical optimization in neglected diseases for paediatric patients by applying the provisional paediatric biopharmaceutical classification system.

Del Moral Sanchez JM, Gonzalez-Alvarez I, Cerda-Revert A, Gonzalez-Alvarez M, Navarro-Ruiz A, Amidon GL, Bermejo M.

Br J Clin Pharmacol. 2018 Oct;84(10):2231-2241. doi: 10.1111/bcp.13650. Epub 2018 Jul 17.

PMID:
29846973
7.

Smart gated magnetic silica mesoporous particles for targeted colon drug delivery: New approaches for inflammatory bowel diseases treatment.

Teruel AH, Pérez-Esteve É, González-Álvarez I, González-Álvarez M, Costero AM, Ferri D, Parra M, Gaviña P, Merino V, Martínez-Mañez R, Sancenón F.

J Control Release. 2018 Jul 10;281:58-69. doi: 10.1016/j.jconrel.2018.05.007. Epub 2018 May 10.

PMID:
29753956
8.

In Vitro Dissolution as a Tool for Formulation Selection: Telmisartan Two-Step IVIVC.

Ruiz Picazo A, Martinez-Martinez MT, Colón-Useche S, Iriarte R, Sánchez-Dengra B, González-Álvarez M, García-Arieta A, González-Álvarez I, Bermejo M.

Mol Pharm. 2018 Jun 4;15(6):2307-2315. doi: 10.1021/acs.molpharmaceut.8b00153. Epub 2018 May 17.

PMID:
29746133
9.

Appropriate use of medical imaging in two Spanish public hospitals: a cross-sectional analysis.

Vilar-Palop J, Hernandez-Aguado I, Pastor-Valero M, Vilar J, González-Alvarez I, Lumbreras B.

BMJ Open. 2018 Mar 16;8(3):e019535. doi: 10.1136/bmjopen-2017-019535.

10.

Ionic Hydrogel Based on Chitosan Cross-Linked with 6-Phosphogluconic Trisodium Salt as a Drug Delivery System.

Martínez-Martínez M, Rodríguez-Berna G, Gonzalez-Alvarez I, Hernández MJ, Corma A, Bermejo M, Merino V, Gonzalez-Alvarez M.

Biomacromolecules. 2018 Apr 9;19(4):1294-1304. doi: 10.1021/acs.biomac.8b00108. Epub 2018 Mar 22.

PMID:
29537830
11.

Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in vivo approach.

Hens B, Bermejo M, Tsume Y, Gonzalez-Alvarez I, Ruan H, Matsui K, Amidon GE, Cavanagh KL, Kuminek G, Benninghoff G, Fan J, Rodríguez-Hornedo N, Amidon GL.

Eur J Pharm Sci. 2018 Mar 30;115:258-269. doi: 10.1016/j.ejps.2018.01.039.

PMID:
29378253
12.

Closed-Loop Doluisio (Colon, Small Intestine) and Single-Pass Intestinal Perfusion (Colon, Jejunum) in Rat-Biophysical Model and Predictions Based on Caco-2.

Lozoya-Agullo I, Gonzalez-Alvarez I, Zur M, Fine-Shamir N, Cohen Y, Markovic M, Garrigues TM, Dahan A, Gonzalez-Alvarez M, Merino-Sanjuán M, Bermejo M, Avdeef A.

Pharm Res. 2017 Dec 29;35(1):2. doi: 10.1007/s11095-017-2331-z.

PMID:
29288412
13.

PLGA nanoparticles are effective to control the colonic release and absorption on ibuprofen.

Lozoya-Agullo I, Araújo F, González-Álvarez I, Merino-Sanjuán M, González-Álvarez M, Bermejo M, Sarmento B.

Eur J Pharm Sci. 2018 Mar 30;115:119-125. doi: 10.1016/j.ejps.2017.12.009. Epub 2017 Dec 14.

PMID:
29248559
14.

Gated Mesoporous Silica Nanocarriers for a "Two-Step" Targeted System to Colonic Tissue.

González-Alvarez M, Coll C, Gonzalez-Alvarez I, Giménez C, Aznar E, Martínez-Bisbal MC, Lozoya-Agulló I, Bermejo M, Martínez-Máñez R, Sancenón F.

Mol Pharm. 2017 Dec 4;14(12):4442-4453. doi: 10.1021/acs.molpharmaceut.7b00565. Epub 2017 Nov 9.

PMID:
29064714
15.

Comparison of segmental-dependent permeability in human and in situ perfusion model in rat.

Ruiz-Picazo A, Lozoya-Agullo I, Ortiz-Azcarate M, Merino-Sanjuán M, González-Álvarez M, González-Álvarez I, Bermejo M.

Eur J Pharm Sci. 2017 Sep 30;107:191-196. doi: 10.1016/j.ejps.2017.06.033. Epub 2017 Jul 4.

PMID:
28687530
16.

Avoiding fears and promoting shared decision-making: How should physicians inform patients about radiation exposure from imaging tests?

Lumbreras B, Vilar J, González-Álvarez I, Guilabert M, Pastor-Valero M, Parker LA, Vilar-Palop J, Hernández-Aguado I.

PLoS One. 2017 Jul 7;12(7):e0180592. doi: 10.1371/journal.pone.0180592. eCollection 2017.

17.

Investigating drug absorption from the colon: Single-pass vs. Doluisio approaches to in-situ rat large-intestinal perfusion.

Lozoya-Agullo I, Zur M, Fine-Shamir N, Markovic M, Cohen Y, Porat D, González-Álvarez I, González-Álvarez M, Merino-Sanjuán M, Bermejo M, Dahan A.

Int J Pharm. 2017 Jul 15;527(1-2):135-141. doi: 10.1016/j.ijpharm.2017.05.018. Epub 2017 May 10.

PMID:
28501438
18.

Usefulness of Caco-2/HT29-MTX and Caco-2/HT29-MTX/Raji B Coculture Models To Predict Intestinal and Colonic Permeability Compared to Caco-2 Monoculture.

Lozoya-Agullo I, Araújo F, González-Álvarez I, Merino-Sanjuán M, González-Álvarez M, Bermejo M, Sarmento B.

Mol Pharm. 2017 Apr 3;14(4):1264-1270. doi: 10.1021/acs.molpharmaceut.6b01165. Epub 2017 Mar 10.

PMID:
28263609
19.

Evaluation of the intestinal permeability of rosemary (Rosmarinus officinalis L.) extract polyphenols and terpenoids in Caco-2 cell monolayers.

Pérez-Sánchez A, Borrás-Linares I, Barrajón-Catalán E, Arráez-Román D, González-Álvarez I, Ibáñez E, Segura-Carretero A, Bermejo M, Micol V.

PLoS One. 2017 Feb 24;12(2):e0172063. doi: 10.1371/journal.pone.0172063. eCollection 2017.

20.

Updated effective doses in radiology.

Vilar-Palop J, Vilar J, Hernández-Aguado I, González-Álvarez I, Lumbreras B.

J Radiol Prot. 2016 Dec;36(4):975-990. Epub 2016 Nov 28. Review.

PMID:
27893456

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