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Items: 18

1.

Proteomic Studies Reveal Disrupted in Schizophrenia 1 as a Player in Both Neurodevelopment and Synaptic Function.

Ramos A, Rodríguez-Seoane C, Rosa I, Gorroño-Etxebarria I, Alonso J, Veiga S, Korth C, Kypta RM, García Á, Requena JR.

Int J Mol Sci. 2018 Dec 29;20(1). pii: E119. doi: 10.3390/ijms20010119.

2.

Recombinant PrPSc shares structural features with brain-derived PrPSc: Insights from limited proteolysis.

Sevillano AM, Fernández-Borges N, Younas N, Wang F, R Elezgarai S, Bravo S, Vázquez-Fernández E, Rosa I, Eraña H, Gil D, Veiga S, Vidal E, Erickson-Beltran ML, Guitián E, Silva CJ, Nonno R, Ma J, Castilla J, R Requena J.

PLoS Pathog. 2018 Jan 31;14(1):e1006797. doi: 10.1371/journal.ppat.1006797. eCollection 2018 Jan.

3.

The human VGF-derived bioactive peptide TLQP-21 binds heat shock 71 kDa protein 8 (HSPA8)on the surface of SH-SY5Y cells.

Akhter S, Chakraborty S, Moutinho D, Álvarez-Coiradas E, Rosa I, Viñuela J, Domínguez E, García A, Requena JR.

PLoS One. 2017 Sep 21;12(9):e0185176. doi: 10.1371/journal.pone.0185176. eCollection 2017.

4.

Alteration of platelet GPVI signaling in ST-elevation myocardial infarction patients demonstrated by a combination of proteomic, biochemical, and functional approaches.

Vélez P, Ocaranza-Sánchez R, López-Otero D, Grigorian-Shamagian L, Rosa I, Guitián E, García-Acuña JM, González-Juanatey JR, García Á.

Sci Rep. 2016 Dec 22;6:39603. doi: 10.1038/srep39603.

5.

The Structural Architecture of an Infectious Mammalian Prion Using Electron Cryomicroscopy.

Vázquez-Fernández E, Vos MR, Afanasyev P, Cebey L, Sevillano AM, Vidal E, Rosa I, Renault L, Ramos A, Peters PJ, Fernández JJ, van Heel M, Young HS, Requena JR, Wille H.

PLoS Pathog. 2016 Sep 8;12(9):e1005835. doi: 10.1371/journal.ppat.1005835. eCollection 2016 Sep.

6.

Proteomic identification of putative biomarkers for early detection of sudden cardiac death in a family with a LMNA gene mutation causing dilated cardiomyopathy.

Izquierdo I, Rosa I, Bravo SB, Guitián E, Pérez-Serra A, Campuzano O, Brugada R, Mangas A, García Á, Toro R.

J Proteomics. 2016 Oct 4;148:75-84. doi: 10.1016/j.jprot.2016.07.020. Epub 2016 Jul 22.

PMID:
27457270
7.

2D-DIGE-based proteomic analysis of intracoronary versus peripheral arterial blood platelets from acute myocardial infarction patients: Upregulation of platelet activation biomarkers at the culprit site.

Vélez P, Ocaranza-Sánchez R, López-Otero D, Grigorian-Shamagian L, Rosa I, Bravo SB, González-Juanatey JR, García Á.

Proteomics Clin Appl. 2016 Aug;10(8):851-8. doi: 10.1002/prca.201500120. Epub 2016 May 23.

PMID:
27095521
8.

Larger aggregates of mutant seipin in Celia's Encephalopathy, a new protein misfolding neurodegenerative disease.

Ruiz-Riquelme A, Sánchez-Iglesias S, Rábano A, Guillén-Navarro E, Domingo-Jiménez R, Ramos A, Rosa I, Senra A, Nilsson P, García Á, Araújo-Vilar D, Requena JR.

Neurobiol Dis. 2015 Nov;83:44-53. doi: 10.1016/j.nbd.2015.08.006. Epub 2015 Aug 15.

PMID:
26282322
9.
10.

Identification of a circulating microvesicle protein network involved in ST-elevation myocardial infarction.

Vélez P, Parguiña AF, Ocaranza-Sánchez R, Grigorian-Shamagian L, Rosa I, Alonso-Orgaz S, de la Cuesta F, Guitián E, Moreu J, Barderas MG, González-Juanatey JR, García Á.

Thromb Haemost. 2014 Oct;112(4):716-26. doi: 10.1160/TH14-04-0337. Epub 2014 Jul 10.

PMID:
25007837
11.

Neuropeptide precursor VGF is genetically associated with social anhedonia and underrepresented in the brain of major mental illness: its downregulation by DISC1.

Ramos A, Rodríguez-Seoane C, Rosa I, Trossbach SV, Ortega-Alonso A, Tomppo L, Ekelund J, Veijola J, Järvelin MR, Alonso J, Veiga S, Sawa A, Hennah W, García A, Korth C, Requena JR.

Hum Mol Genet. 2014 Nov 15;23(22):5859-65. doi: 10.1093/hmg/ddu303. Epub 2014 Jun 16.

12.

A detailed proteomic analysis of rhodocytin-activated platelets reveals novel clues on the CLEC-2 signalosome: implications for CLEC-2 signaling regulation.

Parguiña AF, Alonso J, Rosa I, Vélez P, González-López MJ, Guitián E, Eble JA, Loza MI, García Á.

Blood. 2012 Dec 20;120(26):e117-26. doi: 10.1182/blood-2012-09-456004. Epub 2012 Oct 10. Erratum in: Blood. 2013 Jun 20;121(25):5104. Ebble, Johannes A [corrected to Eble, Johannes A].

PMID:
23053573
13.

Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits.

Bader V, Tomppo L, Trossbach SV, Bradshaw NJ, Prikulis I, Leliveld SR, Lin CY, Ishizuka K, Sawa A, Ramos A, Rosa I, García Á, Requena JR, Hipolito M, Rai N, Nwulia E, Henning U, Ferrea S, Luckhaus C, Ekelund J, Veijola J, Järvelin MR, Hennah W, Korth C.

Hum Mol Genet. 2012 Oct 15;21(20):4406-18. Epub 2012 Jul 13.

14.

Proteomics applied to the study of platelet-related diseases: aiding the discovery of novel platelet biomarkers and drug targets.

Parguiña AF, Rosa I, García A.

J Proteomics. 2012 Dec 5;76 Spec No.:275-86. doi: 10.1016/j.jprot.2012.04.043. Epub 2012 May 8. Review.

PMID:
22579745
15.

Comparative analysis of platelet-derived microparticles reveals differences in their amount and proteome depending on the platelet stimulus.

Shai E, Rosa I, Parguiña AF, Motahedeh S, Varon D, García Á.

J Proteomics. 2012 Dec 5;76 Spec No.:287-96. doi: 10.1016/j.jprot.2012.02.030. Epub 2012 Mar 5.

PMID:
22415276
16.

Variations in platelet proteins associated with ST-elevation myocardial infarction: novel clues on pathways underlying platelet activation in acute coronary syndromes.

Parguiña AF, Grigorian-Shamagian L, Agra RM, López-Otero D, Rosa I, Alonso J, Teijeira-Fernández E, González-Juanatey JR, García Á.

Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):2957-64. doi: 10.1161/ATVBAHA.111.235713. Epub 2011 Sep 15.

PMID:
21921262
17.

Proteins involved in platelet signaling are differentially regulated in acute coronary syndrome: a proteomic study.

Parguiña AF, Grigorian-Shamajian L, Agra RM, Teijeira-Fernández E, Rosa I, Alonso J, Viñuela-Roldán JE, Seoane A, González-Juanatey JR, García A.

PLoS One. 2010 Oct 14;5(10):e13404. doi: 10.1371/journal.pone.0013404. Erratum in: PLoS One. 2011;6(2). doi: 10.1371/annotation/9ef9bdf1-098e-438b-9c97-62f5dd4deb60. Fernández Parguiña, Andrés [corrected to Parguiña, Andrés Fernández].

18.

High-resolution two-dimensional gel electrophoresis analysis of atrial tissue proteome reveals down-regulation of fibulin-1 in atrial fibrillation.

García A, Eiras S, Parguiña AF, Alonso J, Rosa I, Salgado-Somoza A, Rico TY, Teijeira-Fernández E, González-Juanatey JR.

Int J Cardiol. 2011 Aug 4;150(3):283-90. doi: 10.1016/j.ijcard.2010.04.036. Epub 2010 May 6.

PMID:
20451270

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