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Items: 1 to 20 of 155


Manganese Porphyrin-Based SOD Mimetics Produce Polysulfides from Hydrogen Sulfide.

Olson KR, Gao Y, Arif F, Patel S, Yuan X, Mannam V, Howard S, Batinic-Haberle I, Fukuto J, Minnion M, Feelisch M, Straub KD.

Antioxidants (Basel). 2019 Dec 12;8(12). pii: E639. doi: 10.3390/antiox8120639.


The SOD Mimic MnTnHex-2-PyP5+ Reduces the Viability and Migration of 786-O Human Renal Cancer Cells.

Costa JG, Saraiva N, Batinic-Haberle I, Castro M, Oliveira NG, Fernandes AS.

Antioxidants (Basel). 2019 Oct 17;8(10). pii: E490. doi: 10.3390/antiox8100490.


Thiol regulation by Mn porphyrins, commonly known as SOD mimics.

Batinic-Haberle I, Tome ME.

Redox Biol. 2019 Jul;25:101139. doi: 10.1016/j.redox.2019.101139. Epub 2019 Feb 13.


UVB-induced inactivation of manganese-containing superoxide dismutase promotes mitophagy via ROS-mediated mTORC2 pathway activation.

Dhar SK, Batinic-Haberle I, St Clair DK.

J Biol Chem. 2019 Apr 26;294(17):6831-6842. doi: 10.1074/jbc.RA118.006595. Epub 2019 Mar 11.


Disrupting the vicious cycle created by NOX activation in sickle erythrocytes exposed to hypoxia/reoxygenation prevents adhesion and vasoocclusion.

MacKinney A, Woska E, Spasojevic I, Batinic-Haberle I, Zennadi R.

Redox Biol. 2019 Jul;25:101097. doi: 10.1016/j.redox.2019.101097. Epub 2019 Jan 11.


Utilizing Superoxide Dismutase Mimetics to Enhance Radiation Therapy Response While Protecting Normal Tissues.

Mapuskar KA, Anderson CM, Spitz DR, Batinic-Haberle I, Allen BG, E Oberley-Deegan R.

Semin Radiat Oncol. 2019 Jan;29(1):72-80. doi: 10.1016/j.semradonc.2018.10.005. Review.


The manganese(III) porphyrin MnTnHex-2-PyP5+ modulates intracellular ROS and breast cancer cell migration: Impact on doxorubicin-treated cells.

Flórido A, Saraiva N, Cerqueira S, Almeida N, Parsons M, Batinic-Haberle I, Miranda JP, Costa JG, Carrara G, Castro M, Oliveira NG, Fernandes AS.

Redox Biol. 2019 Jan;20:367-378. doi: 10.1016/j.redox.2018.10.016. Epub 2018 Oct 25.


MnSOD is implicated in accelerated wound healing upon Negative Pressure Wound Therapy (NPWT): A case in point for MnSOD mimetics as adjuvants for wound management.

Bellot GL, Dong X, Lahiri A, Sebastin SJ, Batinic-Haberle I, Pervaiz S, Puhaindran ME.

Redox Biol. 2019 Jan;20:307-320. doi: 10.1016/j.redox.2018.10.014. Epub 2018 Oct 23.


Porphyrin-Based SOD Mimic MnTnBu OE -2-PyP5+ Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis.

Anselmo W, Branchetti E, Grau JB, Li G, Ayoub S, Lai EK, Rioux N, Tovmasyan A, Fortier JH, Sacks MS, Batinic-Haberle I, Hazen SL, Levy RJ, Ferrari G.

J Am Heart Assoc. 2018 Oct 16;7(20):e007861. doi: 10.1161/JAHA.117.007861.


Erratum to "Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite" [Free Radic. Biol. Med. 126 (2018) 379-392].

Carballal S, Valez V, Alvarez-Paggi D, Tovmasyan A, Batinic-Haberle I, Ferrer-Sueta G, Murgida DH, Radi R.

Free Radic Biol Med. 2018 Dec;129:611. doi: 10.1016/j.freeradbiomed.2018.10.001. Epub 2018 Oct 11. No abstract available.


Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite.

Carballal S, Valez V, Alvarez-Paggi D, Tovmasyan A, Batinic-Haberle I, Ferrer-Sueta G, Murgida DH, Radi R.

Free Radic Biol Med. 2018 Oct;126:379-392. doi: 10.1016/j.freeradbiomed.2018.08.023. Epub 2018 Aug 23. Erratum in: Free Radic Biol Med. 2018 Dec;129:611.


Sublethal Photodynamic Treatment Does Not Lead to Development of Resistance.

Al-Mutairi R, Tovmasyan A, Batinic-Haberle I, Benov L.

Front Microbiol. 2018 Jul 31;9:1699. doi: 10.3389/fmicb.2018.01699. eCollection 2018.


Mn Porphyrin-Based Redox-Active Drugs: Differential Effects as Cancer Therapeutics and Protectors of Normal Tissue Against Oxidative Injury.

Batinic-Haberle I, Tovmasyan A, Spasojevic I.

Antioxid Redox Signal. 2018 Dec 1;29(16):1691-1724. doi: 10.1089/ars.2017.7453. Epub 2018 Aug 28. Review.


INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice.

Le O, Palacio L, Bernier G, Batinic-Haberle I, Hickson G, Beauséjour C.

Stem Cell Reports. 2018 Jun 5;10(6):1721-1733. doi: 10.1016/j.stemcr.2018.03.025. Epub 2018 Apr 26.


Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning.

Sidlauskaite E, Gibson JW, Megson IL, Whitfield PD, Tovmasyan A, Batinic-Haberle I, Murphy MP, Moult PR, Cobley JN.

Redox Biol. 2018 Jun;16:344-351. doi: 10.1016/j.redox.2018.03.012. Epub 2018 Mar 20.


Post-Irradiation Treatment with a Superoxide Dismutase Mimic, MnTnHex-2-PyP5+, Mitigates Radiation Injury in the Lungs of Non-Human Primates after Whole-Thorax Exposure to Ionizing Radiation.

Cline JM, Dugan G, Bourland JD, Perry DL, Stitzel JD, Weaver AA, Jiang C, Tovmasyan A, Owzar K, Spasojevic I, Batinic-Haberle I, Vujaskovic Z.

Antioxidants (Basel). 2018 Mar 7;7(3). pii: E40. doi: 10.3390/antiox7030040.


Radiation-Mediated Tumor Growth Inhibition Is Significantly Enhanced with Redox-Active Compounds That Cycle with Ascorbate.

Tovmasyan A, Bueno-Janice JC, Jaramillo MC, Sampaio RS, Reboucas JS, Kyui N, Benov L, Deng B, Huang TT, Tome ME, Spasojevic I, Batinic-Haberle I.

Antioxid Redox Signal. 2018 Nov 1;29(13):1196-1214. doi: 10.1089/ars.2017.7218. Epub 2018 Mar 27.


Whole thorax irradiation of non-human primates induces persistent nuclear damage and gene expression changes in peripheral blood cells.

Ghandhi SA, Turner HC, Shuryak I, Dugan GO, Bourland JD, Olson JD, Tooze JA, Morton SR, Batinic-Haberle I, Cline JM, Amundson SA.

PLoS One. 2018 Jan 19;13(1):e0191402. doi: 10.1371/journal.pone.0191402. eCollection 2018.


Post-illumination cellular effects of photodynamic treatment.

Charara M, Tovmasyan A, Batinic-Haberle I, Craik J, Benov L.

PLoS One. 2017 Dec 4;12(12):e0188535. doi: 10.1371/journal.pone.0188535. eCollection 2017.


Cationic amphiphilic Zn-porphyrin with high antifungal photodynamic potency.

Moghnie S, Tovmasyan A, Craik J, Batinic-Haberle I, Benov L.

Photochem Photobiol Sci. 2017 Nov 8;16(11):1709-1716. doi: 10.1039/c7pp00143f.


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