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Dispersibility and Storage Stability Optimization of High Dose Isoniazid Dry Powder Inhalation Formulations with L-Leucine or Trileucine.

Sibum I, Hagedoorn P, Kluitman MPG, Kloezen M, Frijlink HW, Grasmeijer F.

Pharmaceutics. 2019 Dec 25;12(1). pii: E24. doi: 10.3390/pharmaceutics12010024.


Characterization and Formulation of Isoniazid for High-Dose Dry Powder Inhalation.

Sibum I, Hagedoorn P, Frijlink HW, Grasmeijer F.

Pharmaceutics. 2019 May 13;11(5). pii: E233. doi: 10.3390/pharmaceutics11050233.


Challenges for pulmonary delivery of high powder doses.

Sibum I, Hagedoorn P, de Boer AH, Frijlink HW, Grasmeijer F.

Int J Pharm. 2018 Sep 5;548(1):325-336. doi: 10.1016/j.ijpharm.2018.07.008. Epub 2018 Jul 2. Review.

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