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Items: 1 to 20 of 25

1.

Telomeres and Longevity: A Cause or an Effect?

Adwan Shekhidem H, Sharvit L, Leman E, Manov I, Roichman A, Holtze S, M Huffman D, Y Cohen H, Bernd Hildebrandt T, Shams I, Atzmon G.

Int J Mol Sci. 2019 Jul 1;20(13). pii: E3233. doi: 10.3390/ijms20133233.

2.

The transcriptome landscape of the carcinogenic treatment response in the blind mole rat: insights into cancer resistance mechanisms.

Altwasser R, Paz A, Korol A, Manov I, Avivi A, Shams I.

BMC Genomics. 2019 Jan 8;20(1):17. doi: 10.1186/s12864-018-5417-z.

3.

Reduced calcium influx in the hypoxia-tolerant Spalax: The role of the erythropoietin receptor.

Salah-Hussiesy S, Mamchur A, Odeh A, Domankevich V, Shams I.

Cell Calcium. 2018 Sep;74:123-130. doi: 10.1016/j.ceca.2018.07.004. Epub 2018 Jul 17.

PMID:
30048878
4.

Adipose-Derived Stem Cells of Blind Mole Rat Spalax Exhibit Reduced Homing Ability: Molecular Mechanisms and Potential Role in Cancer Suppression.

Mamchur A, Leman E, Salah S, Avivi A, Shams I, Manov I.

Stem Cells. 2018 Oct;36(10):1630-1642. doi: 10.1002/stem.2884. Epub 2018 Jul 29.

PMID:
30004601
5.

Soluble Mediators Produced by Pro-Resolving Macrophages Inhibit Angiogenesis.

Michaeli S, Dakwar V, Weidenfeld K, Granski O, Gilon O, Schif-Zuck S, Mamchur A, Shams I, Barkan D.

Front Immunol. 2018 Apr 25;9:768. doi: 10.3389/fimmu.2018.00768. eCollection 2018.

6.

Postnatal Exocrine Pancreas Growth by Cellular Hypertrophy Correlates with a Shorter Lifespan in Mammals.

Anzi S, Stolovich-Rain M, Klochendler A, Fridlich O, Helman A, Paz-Sonnenfeld A, Avni-Magen N, Kaufman E, Ginzberg MB, Snider D, Ray S, Brecht M, Holmes MM, Meir K, Avivi A, Shams I, Berkowitz A, Shapiro AMJ, Glaser B, Ben-Sasson S, Kafri R, Dor Y.

Dev Cell. 2018 Jun 18;45(6):726-737.e3. doi: 10.1016/j.devcel.2018.05.024.

7.

Resistance to DNA damage and enhanced DNA repair capacity in the hypoxia-tolerant blind mole rat Spalax carmeli.

Domankevich V, Eddini H, Odeh A, Shams I.

J Exp Biol. 2018 Apr 20;221(Pt 8). pii: jeb174540. doi: 10.1242/jeb.174540.

8.

Intraspecific and intraorganismal copy number dynamics of retrotransposons and tandem repeat in Aegilops speltoides Tausch (Poaceae, Triticeae).

Shams I, Raskina O.

Protoplasma. 2018 Jul;255(4):1023-1038. doi: 10.1007/s00709-018-1212-6. Epub 2018 Jan 27.

PMID:
29374788
9.

Hypoxia tolerance, longevity and cancer-resistance in the mole rat Spalax - a liver transcriptomics approach.

Schmidt H, Malik A, Bicker A, Poetzsch G, Avivi A, Shams I, Hankeln T.

Sci Rep. 2017 Oct 30;7(1):14348. doi: 10.1038/s41598-017-13905-z.

10.

Genome maintenance and bioenergetics of the long-lived hypoxia-tolerant and cancer-resistant blind mole rat, Spalax: a cross-species analysis of brain transcriptome.

Malik A, Domankevich V, Lijuan H, Xiaodong F, Korol A, Avivi A, Shams I.

Sci Rep. 2016 Dec 9;6:38624. doi: 10.1038/srep38624.

11.

Adaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat Spalax.

Domankevich V, Opatowsky Y, Malik A, Korol AB, Frenkel Z, Manov I, Avivi A, Shams I.

BMC Evol Biol. 2016 Sep 2;16:177. doi: 10.1186/s12862-016-0743-8.

12.

Molecular evolution of antioxidant and hypoxia response in long-lived, cancer-resistant blind mole rats: The Nrf2-Keap1 pathway.

Schmidt H, Hangmann J, Shams I, Avivi A, Hankeln T.

Gene. 2016 Feb 15;577(2):293-8. doi: 10.1016/j.gene.2015.11.038. Epub 2015 Nov 26.

PMID:
26631622
13.

Corrigendum: Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax.

Fang X, Nevo E, Han L, Levanon EY, Zhao J, Avivi A, Larkin D, Jiang X, Feranchuk S, Zhu Y, Fishman A, Feng Y, Sher N, Xiong Z, Hankeln T, Huang Z, Gorbunova V, Zhang L, Zhao W, Wildman DE, Xiong Y, Gudkov A, Zheng Q, Rechavi G, Liu S, Bazak L, Chen J, Knisbacher BA, Lu Y, Shams I, Gajda K, Farré M, Kim J, Lewin HA, Ma J, Band M, Bicker A, Kranz A, Mattheus T, Schmidt H, Seluanov A, Azpurua J, McGowen MR, Ben Jacob E, Li K, Peng S, Zhu X, Liao X, Li S, Krogh A, Zhou X, Brodsky L, Wang J.

Nat Commun. 2015 Aug 12;6:8051. doi: 10.1038/ncomms9051. No abstract available.

PMID:
26264976
14.

Iron-rich ferritin in the hypoxia-tolerant rodent Spalax ehrenbergi: a naturally-occurring biomarker confirms the internalization and pathways of intracellular macromolecules.

Iancu TC, Arad T, Shams I, Manov I.

J Struct Biol. 2014 Sep;187(3):254-265. doi: 10.1016/j.jsb.2014.07.002. Epub 2014 Jul 19.

PMID:
25050761
15.

Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax.

Fang X, Nevo E, Han L, Levanon EY, Zhao J, Avivi A, Larkin D, Jiang X, Feranchuk S, Zhu Y, Fishman A, Feng Y, Sher N, Xiong Z, Hankeln T, Huang Z, Gorbunova V, Zhang L, Zhao W, Wildman DE, Xiong Y, Gudkov A, Zheng Q, Rechavi G, Liu S, Bazak L, Chen J, Knisbacher BA, Lu Y, Shams I, Gajda K, Farré M, Kim J, Lewin HA, Ma J, Band M, Bicker A, Kranz A, Mattheus T, Schmidt H, Seluanov A, Azpurua J, McGowen MR, Ben Jacob E, Li K, Peng S, Zhu X, Liao X, Li S, Krogh A, Zhou X, Brodsky L, Wang J.

Nat Commun. 2014 Jun 3;5:3966. doi: 10.1038/ncomms4966. Erratum in: Nat Commun. 2015;6:8051.

PMID:
24892994
16.

Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitro evidence.

Manov I, Hirsh M, Iancu TC, Malik A, Sotnichenko N, Band M, Avivi A, Shams I.

BMC Biol. 2013 Aug 9;11:91. doi: 10.1186/1741-7007-11-91.

17.

Transcription pattern of p53-targeted DNA repair genes in the hypoxia-tolerant subterranean mole rat Spalax.

Shams I, Malik A, Manov I, Joel A, Band M, Avivi A.

J Mol Biol. 2013 Apr 12;425(7):1111-8. doi: 10.1016/j.jmb.2013.01.007. Epub 2013 Jan 11.

PMID:
23318952
18.
19.

An extracellular region of the erythropoietin receptor of the subterranean blind mole rat Spalax enhances receptor maturation.

Ravid O, Shams I, Ben Califa N, Nevo E, Avivi A, Neumann D.

Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14360-5. Epub 2007 Aug 27.

20.

Lacrimo-auriculo-dento-digital syndrome is caused by reduced activity of the fibroblast growth factor 10 (FGF10)-FGF receptor 2 signaling pathway.

Shams I, Rohmann E, Eswarakumar VP, Lew ED, Yuzawa S, Wollnik B, Schlessinger J, Lax I.

Mol Cell Biol. 2007 Oct;27(19):6903-12. Epub 2007 Aug 6.

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