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Items: 1 to 20 of 61


Promises and Pitfalls of In Vivo Evolution to Improve Phage Therapy.

Bull JJ, Levin BR, Molineux IJ.

Viruses. 2019 Nov 21;11(12). pii: E1083. doi: 10.3390/v11121083.


Structural dynamics of bacteriophage P22 infection initiation revealed by cryo-electron tomography.

Wang C, Tu J, Liu J, Molineux IJ.

Nat Microbiol. 2019 Jun;4(6):1049-1056. doi: 10.1038/s41564-019-0403-z. Epub 2019 Mar 18.


Directed in Vitro Evolution of Therapeutic Bacteriophages: The Appelmans Protocol.

Burrowes BH, Molineux IJ, Fralick JA.

Viruses. 2019 Mar 11;11(3). pii: E241. doi: 10.3390/v11030241.


Antibiotic Therapy Using Phage Depolymerases: Robustness Across a Range of Conditions.

Lin H, Paff ML, Molineux IJ, Bull JJ.

Viruses. 2018 Nov 12;10(11). pii: E622. doi: 10.3390/v10110622.


Experimental evolution of UV resistance in a phage.

Tom EF, Molineux IJ, Paff ML, Bull JJ.

PeerJ. 2018 Jul 9;6:e5190. doi: 10.7717/peerj.5190. eCollection 2018.


Viral attenuation by engineered protein fragmentation.

Garry DJ, Ellington AD, Molineux IJ, Bull JJ.

Virus Evol. 2018 Jun 19;4(1):vey017. doi: 10.1093/ve/vey017. eCollection 2018 Jan.


Therapeutic Application of Phage Capsule Depolymerases against K1, K5, and K30 Capsulated E. coli in Mice.

Lin H, Paff ML, Molineux IJ, Bull JJ.

Front Microbiol. 2017 Nov 16;8:2257. doi: 10.3389/fmicb.2017.02257. eCollection 2017.


A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease.

Szymanski MR, Yu W, Gmyrek AM, White MA, Molineux IJ, Lee JC, Yin YW.

Nat Commun. 2017 May 3;8:14959. doi: 10.1038/ncomms14959.


Dual host specificity of phage SP6 is facilitated by tailspike rotation.

Tu J, Park T, Morado DR, Hughes KT, Molineux IJ, Liu J.

Virology. 2017 Jul;507:206-215. doi: 10.1016/j.virol.2017.04.017. Epub 2017 Apr 26.


Design and engineering of a transmissible antiviral defense.

Paff ML, Nuismer SL, Ellington AD, Molineux IJ, May RH, Bull JJ.

J Biol Eng. 2016 Oct 12;10:12. eCollection 2016.


Evolved Populations of Shigella flexneri Phage Sf6 Acquire Large Deletions, Altered Genomic Architecture, and Faster Life Cycles.

Dover JA, Burmeister AR, Molineux IJ, Parent KN.

Genome Biol Evol. 2016 Sep 19;8(9):2827-40. doi: 10.1093/gbe/evw177.


Ultrastructural analysis of bacteriophage Φ29 during infection of Bacillus subtilis.

Farley MM, Tu J, Kearns DB, Molineux IJ, Liu J.

J Struct Biol. 2017 Feb;197(2):163-171. doi: 10.1016/j.jsb.2016.07.019. Epub 2016 Jul 29.


Virus wars: using one virus to block the spread of another.

Paff ML, Nuismer SL, Ellington A, Molineux IJ, Bull JJ.

PeerJ. 2016 Jun 29;4:e2166. doi: 10.7717/peerj.2166. eCollection 2016.


Rapid Detection of Viable Bacillus anthracis Spores in Environmental Samples by Using Engineered Reporter Phages.

Sharp NJ, Molineux IJ, Page MA, Schofield DA.

Appl Environ Microbiol. 2016 Apr 4;82(8):2380-2387. doi: 10.1128/AEM.03772-15. Print 2016 Apr.


The T7 ejection nanomachine components gp15-gp16 form a spiral ring complex that binds DNA and a lipid membrane.

Lupo D, Leptihn S, Nagler G, Haase M, J Molineux I, Kuhn A.

Virology. 2015 Dec;486:263-71. doi: 10.1016/j.virol.2015.09.022. Epub 2015 Oct 27.


Structural remodeling of bacteriophage T4 and host membranes during infection initiation.

Hu B, Margolin W, Molineux IJ, Liu J.

Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4919-28. doi: 10.1073/pnas.1501064112. Epub 2015 Aug 17.


Rapid Detection of Bacillus anthracis in Complex Food Matrices Using Phage-Mediated Bioluminescence.

Sharp NJ, Vandamm JP, Molineux IJ, Schofield DA.

J Food Prot. 2015 May;78(5):963-8. doi: 10.4315/0362-028X.JFP-14-534.


Introduction to “Viruses of Microbes III” special section of Virology.

Leiman PG, Molineux IJ.

Virology. 2015 Mar;477:99. doi: 10.1016/j.virol.2015.01.001. Epub 2015 Feb 7. No abstract available.


Synergy as a rationale for phage therapy using phage cocktails.

Schmerer M, Molineux IJ, Bull JJ.

PeerJ. 2014 Sep 25;2:e590. doi: 10.7717/peerj.590. eCollection 2014.


Challenges in predicting the evolutionary maintenance of a phage transgene.

Schmerer M, Molineux IJ, Ally D, Tyerman J, Cecchini N, Bull JJ.

J Biol Eng. 2014 Aug 1;8:21. doi: 10.1186/1754-1611-8-21. eCollection 2014.

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