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Ternary nanocomposite carriers based on organic clay-lipid vesicles as an effective colon-targeted drug delivery system: preparation and in vitro/in vivo characterization.

Kim HY, Cheon JH, Lee SH, Min JY, Back SY, Song JG, Kim DH, Lim SJ, Han HK.

J Nanobiotechnology. 2020 Jan 21;18(1):17. doi: 10.1186/s12951-020-0579-7.


Strategic Approaches for Colon Targeted Drug Delivery: An Overview of Recent Advancements.

Lee SH, Bajracharya R, Min JY, Han JW, Park BJ, Han HK.

Pharmaceutics. 2020 Jan 15;12(1). pii: E68. doi: 10.3390/pharmaceutics12010068. Review.


Recent Advancements in Non-Invasive Formulations for Protein Drug Delivery.

Bajracharya R, Song JG, Back SY, Han HK.

Comput Struct Biotechnol J. 2019 Sep 11;17:1290-1308. doi: 10.1016/j.csbj.2019.09.004. eCollection 2019. Review.


Development of pH-responsive organic-inorganic hybrid nanocomposites as an effective oral delivery system of protein drugs.

Lee SH, Song JG, Han HK.

J Control Release. 2019 Oct;311-312:74-84. doi: 10.1016/j.jconrel.2019.08.036. Epub 2019 Sep 2.


Multilayer-Coated Tablet of Clopidogrel and Rosuvastatin: Preparation and In Vitro/In vivo Characterization.

Seo KS, Han HK.

Pharmaceutics. 2019 Jul 4;11(7). pii: E313. doi: 10.3390/pharmaceutics11070313.


Correction to: Nanomedicines: current status and future perspectives in aspect of drug delivery and pharmacokinetics.

Choi YH, Han HK.

J Pharm Investig. 2019;49(1):201. doi: 10.1007/s40005-018-00412-0. Epub 2018 Nov 5.


Development of a Ternary Solid Dispersion Formulation of LW6 to Improve the In Vivo Activity as a BCRP Inhibitor: Preparation and In Vitro/In Vivo Characterization.

Bajracharya R, Lee SH, Song JG, Kim M, Lee K, Han HK.

Pharmaceutics. 2019 May 1;11(5). pii: E206. doi: 10.3390/pharmaceutics11050206.


Nanomedicines: current status and future perspectives in aspect of drug delivery and pharmacokinetics.

Choi YH, Han HK.

J Pharm Investig. 2018;48(1):43-60. doi: 10.1007/s40005-017-0370-4. Epub 2017 Nov 28. Review. Erratum in: J Pharm Investig. 2019;49(1):201.


Improved In vivo Effect of Chrysin as an Absorption Enhancer Via the Preparation of Ternary Solid Dispersion with BrijĀ®L4 and Aminoclay.

Lee SH, Lee YS, Song JG, Han HK.

Curr Drug Deliv. 2019;16(1):86-92. doi: 10.2174/1567201815666180924151458.


Development of a docetaxel micellar formulation using poly(ethylene glycol)-polylactide-poly(ethylene glycol) (PEG-PLA-PEG) with successful reconstitution for tumor targeted drug delivery.

Sim T, Kim JE, Hoang NH, Kang JK, Lim C, Kim DS, Lee ES, Youn YS, Choi HG, Han HK, Weon KY, Oh KT.

Drug Deliv. 2018 Nov;25(1):1362-1371. doi: 10.1080/10717544.2018.1477865.


Enhanced oral absorption of sorafenib via the layer-by-layer deposition of a pH-sensitive polymer and glycol chitosan on the liposome.

Zhao M, Lee SH, Song JG, Kim HY, Han HK.

Int J Pharm. 2018 Jun 10;544(1):14-20. doi: 10.1016/j.ijpharm.2018.04.020. Epub 2018 Apr 12.


Piperine-mediated drug interactions and formulation strategy for piperine: recent advances and future perspectives.

Lee SH, Kim HY, Back SY, Han HK.

Expert Opin Drug Metab Toxicol. 2018 Jan;14(1):43-57. doi: 10.1080/17425255.2018.1418854. Epub 2017 Dec 19. Review.


PEGylated hyaluronic acid-coated liposome for enhanced in vivo efficacy of sorafenib via active tumor cell targeting and prolonged systemic exposure.

Mo L, Song JG, Lee H, Zhao M, Kim HY, Lee YJ, Ko HW, Han HK.

Nanomedicine. 2018 Feb;14(2):557-567. doi: 10.1016/j.nano.2017.12.003. Epub 2017 Dec 14.


Electrostatic interaction of tumor-targeting adenoviruses with aminoclay acquires enhanced infectivity to tumor cells inside the bladder and has better cytotoxic activity.

Kim SY, Kwon WA, Shin SP, Seo HK, Lim SJ, Jung YS, Han HK, Jeong KC, Lee SJ.

Drug Deliv. 2018 Nov;25(1):49-58. doi: 10.1080/10717544.2017.1413450.


Biophysical evaluation of aminoclay as an effective protectant for protein stabilization during freeze-drying and storage.

Song JG, Lee SH, Han HK.

Int J Nanomedicine. 2016 Dec 12;11:6609-6619. doi: 10.2147/IJN.S122726. eCollection 2016.


Aminoclay as a highly effective cationic vehicle for enhancing adenovirus-mediated gene transfer through nanobiohybrid complex formation.

Kim SY, Lee SJ, Han HK, Lim SJ.

Acta Biomater. 2017 Feb;49:521-530. doi: 10.1016/j.actbio.2016.11.045. Epub 2016 Nov 18.


Discovery of LW6 as a new potent inhibitor of breast cancer resistance protein.

Song JG, Lee YS, Park JA, Lee EH, Lim SJ, Yang SJ, Zhao M, Lee K, Han HK.

Cancer Chemother Pharmacol. 2016 Oct;78(4):735-44. doi: 10.1007/s00280-016-3127-2. Epub 2016 Aug 12.


Aminoclay-lipid hybrid composite as a novel drug carrier of fenofibrate for the enhancement of drug release and oral absorption.

Yang L, Shao Y, Han HK.

Int J Nanomedicine. 2016 Mar 15;11:1067-76. doi: 10.2147/IJN.S101116. eCollection 2016.


Alteration of the intravenous and oral pharmacokinetics of valsartan via the concurrent use of gemfibrozil in rats.

Yang SJ, Kim BJ, Mo L, Han HK.

Biopharm Drug Dispos. 2016 Jul;37(5):245-51. doi: 10.1002/bdd.2001.


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