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Items: 19


Multitarget-directed cotreatment with cilostazol and aripiprazole for augmented neuroprotection against oxidative stress-induced toxicity in HT22 mouse hippocampal cells.

Lee YS, Park SY, Heo HJ, Lee WS, Hong KW, Kim CD.

Eur J Pharmacol. 2019 Aug 15;857:172454. doi: 10.1016/j.ejphar.2019.172454. Epub 2019 Jun 13.


Augmented improvement of cognition and memory by aripiprazole add-on for cilostazol treatment in the chronic cerebral hypoperfusion mouse model.

Park SY, Kim HY, Lee YS, Heo HJ, Shin HK, Lee WS, Hong KW, Kim CD.

Behav Brain Res. 2019 Jun 3;365:133-140. doi: 10.1016/j.bbr.2019.03.013. Epub 2019 Mar 6.


A Novel Atypical PKC-Iota Inhibitor, Echinochrome A, Enhances Cardiomyocyte Differentiation from Mouse Embryonic Stem Cells.

Kim HK, Cho SW, Heo HJ, Jeong SH, Kim M, Ko KS, Rhee BD, Mishchenko NP, Vasileva EA, Fedoreyev SA, Stonik VA, Han J.

Mar Drugs. 2018 Jun 2;16(6). pii: E192. doi: 10.3390/md16060192.


Generation of PDGFRα+ Cardioblasts from Pluripotent Stem Cells.

Hong SP, Song S, Cho SW, Lee S, Koh BI, Bae H, Kim KH, Park JS, Do HS, Im I, Heo HJ, Ko TH, Park JH, Youm JB, Kim SJ, Kim I, Han J, Han YM, Koh GY.

Sci Rep. 2017 Feb 6;7:41840. doi: 10.1038/srep41840.


Mitochondrial pyruvate dehydrogenase phosphatase 1 regulates the early differentiation of cardiomyocytes from mouse embryonic stem cells.

Heo HJ, Kim HK, Youm JB, Cho SW, Song IS, Lee SY, Ko TH, Kim N, Ko KS, Rhee BD, Han J.

Exp Mol Med. 2016 Aug 19;48(8):e254. doi: 10.1038/emm.2016.70.


FOXM1-Induced PRX3 Regulates Stemness and Survival of Colon Cancer Cells via Maintenance of Mitochondrial Function.

Song IS, Jeong YJ, Jeong SH, Heo HJ, Kim HK, Bae KB, Park YH, Kim SU, Kim JM, Kim N, Ko KS, Rhee BD, Han J.

Gastroenterology. 2015 Oct;149(4):1006-16.e9. doi: 10.1053/j.gastro.2015.06.007. Epub 2015 Jun 17.


Low abundance of mitochondrial DNA changes mitochondrial status and renders cells resistant to serum starvation and sodium nitroprusside insult.

Lee SR, Heo HJ, Jeong SH, Kim HK, Song IS, Ko KS, Rhee BD, Kim N, Han J.

Cell Biol Int. 2015 Jul;39(7):865-72. doi: 10.1002/cbin.10473. Epub 2015 Apr 27.


Modeling of stochastic behavior of pacemaker potential in interstitial cells of Cajal.

Youm JB, Leem CH, Lee SR, Song IS, Kim HK, Heo HJ, Kim BJ, Kim N, Han J.

Prog Biophys Mol Biol. 2014 Sep;116(1):56-69. doi: 10.1016/j.pbiomolbio.2014.09.002. Epub 2014 Sep 17.


B7-H4 downregulation induces mitochondrial dysfunction and enhances doxorubicin sensitivity via the cAMP/CREB/PGC1-α signaling pathway in HeLa cells.

Kim HK, Song IS, Lee SY, Jeong SH, Lee SR, Heo HJ, Thu VT, Kim N, Ko KS, Rhee BD, Jeong DH, Kim YN, Han J.

Pflugers Arch. 2014 Dec;466(12):2323-38.


Dual modulation of the mitochondrial permeability transition pore and redox signaling synergistically promotes cardiomyocyte differentiation from pluripotent stem cells.

Cho SW, Park JS, Heo HJ, Park SW, Song S, Kim I, Han YM, Yamashita JK, Youm JB, Han J, Koh GY.

J Am Heart Assoc. 2014 Mar 13;3(2):e000693. doi: 10.1161/JAHA.113.000693.


Combination treatment with 2-methoxyestradiol overcomes bortezomib resistance of multiple myeloma cells.

Song IS, Jeong YJ, Jeong SH, Heo HJ, Kim HK, Lee SR, Ko TH, Youm JB, Kim N, Ko KS, Rhee BD, Han J.

Exp Mol Med. 2013 Oct 25;45:e50. doi: 10.1038/emm.2013.104.


Glucocorticoids and their receptors: insights into specific roles in mitochondria.

Lee SR, Kim HK, Song IS, Youm J, Dizon LA, Jeong SH, Ko TH, Heo HJ, Ko KS, Rhee BD, Kim N, Han J.

Prog Biophys Mol Biol. 2013 May;112(1-2):44-54. doi: 10.1016/j.pbiomolbio.2013.04.001. Epub 2013 Apr 16. Review.


Beta adrenergic overstimulation impaired vascular contractility via actin-cytoskeleton disorganization in rabbit cerebral artery.

Kim HK, Park WS, Warda M, Park SY, Ko EA, Kim MH, Jeong SH, Heo HJ, Choi TH, Hwang YW, Lee SI, Ko KS, Rhee BD, Kim N, Han J.

PLoS One. 2012;7(8):e43884. doi: 10.1371/journal.pone.0043884. Epub 2012 Aug 20.


NecroX-5 prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter.

Thu VT, Kim HK, Long le T, Lee SR, Hanh TM, Ko TH, Heo HJ, Kim N, Kim SH, Ko KS, Rhee BD, Han J.

Cardiovasc Res. 2012 May 1;94(2):342-50. doi: 10.1093/cvr/cvs122. Epub 2012 Mar 16. Erratum in: Cardiovasc Res. 2012 Jul 1;95(1):134.


Cardiac proteomic responses to ischemia-reperfusion injury and ischemic preconditioning.

Kim HK, Thu VT, Heo HJ, Kim N, Han J.

Expert Rev Proteomics. 2011 Apr;8(2):241-61. doi: 10.1586/epr.11.8. Review.


Increased sensitivity of serotonin on the voltage-dependent K+ channels in mesenteric arterial smooth muscle cells of OLETF rats.

Ko EA, Park WS, Firth AL, Hong DH, Choi SW, Heo HJ, Kim MH, Noh JH, Ko JH, Kim N, Earm YE, Song DK, Han J.

Prog Biophys Mol Biol. 2010 Sep;103(1):88-94. doi: 10.1016/j.pbiomolbio.2010.02.003. Epub 2010 Feb 26. Review.


Endogenous angiotensin II enhances atherogenesis in apoprotein E-deficient mice with renovascular hypertension through activation of vascular smooth muscle cells.

Heo HJ, Yun MR, Jung KH, Lee JY, Park JY, Lee SJ, Bae SS, Lee WS, Kim CD.

Life Sci. 2007 Feb 20;80(11):1057-63. Epub 2006 Dec 15.


4-Hydroxynonenal induces vascular smooth muscle cell apoptosis through mitochondrial generation of reactive oxygen species.

Lee JY, Jung GY, Heo HJ, Yun MR, Park JY, Bae SS, Hong KW, Lee WS, Kim CD.

Toxicol Lett. 2006 Oct 25;166(3):212-21. Epub 2006 Jul 15.


Oleic acid enhances vascular smooth muscle cell proliferation via phosphatidylinositol 3-kinase/Akt signaling pathway.

Yun MR, Lee JY, Park HS, Heo HJ, Park JY, Bae SS, Hong KW, Sung SM, Kim CD.

Pharmacol Res. 2006 Aug;54(2):97-102. Epub 2006 Mar 22.


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