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Items: 1 to 20 of 42


Economic Impact of Pharmacist-Participated Medication Management for Elderly Patients in Nursing Homes: A Systematic Review.

Kwak A, Moon YJ, Song YK, Yun HY, Kim K.

Int J Environ Res Public Health. 2019 Aug 16;16(16). pii: E2955. doi: 10.3390/ijerph16162955. Review.


Model based development of tacrolimus dosing algorithm considering CYP3A5 genotypes and mycophenolate mofetil drug interaction in stable kidney transplant recipients.

Kim JH, Han N, Kim MG, Kim YW, Jang H, Yun HY, Yu MY, Kim IW, Kim YS, Oh JM.

Sci Rep. 2019 Aug 13;9(1):11740. doi: 10.1038/s41598-019-47876-0.


Application of Size and Maturation Functions to Population Pharmacokinetic Modeling of Pediatric Patients.

Back HM, Lee JB, Han N, Goo S, Jung E, Kim J, Song B, An SH, Kim JT, Rhie SJ, Ree YS, Chae JW, Kim J, Yun HY.

Pharmaceutics. 2019 Jun 3;11(6). pii: E259. doi: 10.3390/pharmaceutics11060259.


Dose Optimization Based on Population Pharmacokinetic Modeling of High-Dose Cyclosporine, a P-glycoprotein Inhibitor, in Combination with Systemic Chemotherapy in Pediatric Patients with Retinoblastoma.

Ree YS, Back HM, Yun HY, Ahn JH, Son ES, Han JW, Lyu CJ, Rhie SJ.

J Ocul Pharmacol Ther. 2018 Nov;34(9):647-655. doi: 10.1089/jop.2018.0041. Epub 2018 Oct 18.


Prediction of Methionine and Homocysteine levels in Zucker diabetic fatty (ZDF) rats as a T2DM animal model after consumption of a Methionine-rich diet.

Han N, Chae JW, Jeon J, Lee J, Back HM, Song B, Kwon KI, Kim SK, Yun HY.

Nutr Metab (Lond). 2018 Feb 10;15:14. doi: 10.1186/s12986-018-0247-1. eCollection 2018.


Increased Exposure of Tacrolimus by Co-administered Mycophenolate Mofetil: Population Pharmacokinetic Analysis in Healthy Volunteers.

Kim JH, Han N, Kim MG, Yun HY, Lee S, Bae E, Kim YS, Kim IW, Oh JM.

Sci Rep. 2018 Jan 26;8(1):1687. doi: 10.1038/s41598-018-20071-3.


A mechanism-based pharmacokinetic model of fenofibrate for explaining increased drug absorption after food consumption.

Back HM, Song B, Pradhan S, Chae JW, Han N, Kang W, Chang MJ, Zheng J, Kwon KI, Karlsson MO, Yun HY.

BMC Pharmacol Toxicol. 2018 Jan 25;19(1):4. doi: 10.1186/s40360-018-0194-5.


Performance comparison of first-order conditional estimation with interaction and Bayesian estimation methods for estimating the population parameters and its distribution from data sets with a low number of subjects.

Pradhan S, Song B, Lee J, Chae JW, Kim KI, Back HM, Han N, Kwon KI, Yun HY.

BMC Med Res Methodol. 2017 Dec 1;17(1):154. doi: 10.1186/s12874-017-0427-0.


External evaluation of population pharmacokinetic models for ciclosporin in adult renal transplant recipients.

Mao JJ, Jiao Z, Yun HY, Zhao CY, Chen HC, Qiu XY, Zhong MK.

Br J Clin Pharmacol. 2018 Jan;84(1):153-171. doi: 10.1111/bcp.13431. Epub 2017 Nov 3.


Development of a LC-MS/MS method for the determination of CKD-712 in rat plasma: Application to a pharmacokinetic study in rats.

Chae JW, Yun HY, Eom HY, Jeong EJ, Koo TS, Kwon KI, Lee JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 1;1061-1062:123-127. doi: 10.1016/j.jchromb.2017.07.011. Epub 2017 Jul 8.


Age-Related Changes in Sulfur Amino Acid Metabolism in Male C57BL/6 Mice.

Jeon JS, Oh JJ, Kwak HC, Yun HY, Kim HC, Kim YM, Oh SJ, Kim SK.

Biomol Ther (Seoul). 2018 Mar 1;26(2):167-174. doi: 10.4062/biomolther.2017.054.


Population pharmacokinetics of moxifloxacin, cycloserine, p-aminosalicylic acid and kanamycin for the treatment of multi-drug-resistant tuberculosis.

Chang MJ, Jin B, Chae JW, Yun HY, Kim ES, Lee YJ, Cho YJ, Yoon HI, Lee CT, Park KU, Song J, Lee JH, Park JS.

Int J Antimicrob Agents. 2017 Jun;49(6):677-687. doi: 10.1016/j.ijantimicag.2017.01.024. Epub 2017 Apr 10.


Quantitative analysis of lab-to-lab variability in Caco-2 permeability assays.

Lee JB, Zgair A, Taha DA, Zang X, Kagan L, Kim TH, Kim MG, Yun HY, Fischer PM, Gershkovich P.

Eur J Pharm Biopharm. 2017 May;114:38-42. doi: 10.1016/j.ejpb.2016.12.027. Epub 2017 Jan 12.


BSA and ABCB1 polymorphism affect the pharmacokinetics of sunitinib and its active metabolite in Asian mRCC patients receiving an attenuated sunitinib dosing regimen.

Chae JW, Teo YL, Ho HK, Lee J, Back HM, Yun HY, Karlsson MO, Kwon KI, Chan A.

Cancer Chemother Pharmacol. 2016 Sep;78(3):623-32. doi: 10.1007/s00280-016-3104-9. Epub 2016 Aug 2.


A novel HPLC-MS/MS method for the simultaneous determination of astemizole and its major metabolite in dog or monkey plasma and application to pharmacokinetics.

Back HM, Lee JH, Chae JW, Song B, Seo JW, Yun HY, Kwon KI.

J Pharm Biomed Anal. 2015 Oct 10;114:121-6. doi: 10.1016/j.jpba.2015.04.036. Epub 2015 May 21.


Population pharmacokinetics of cyclosporine in hematopoietic stem cell transplant patients: consideration of genetic polymorphisms.

Kim MG, Kim IW, Choi B, Han N, Yun HY, Park S, Oh JM.

Ann Pharmacother. 2015 Jun;49(6):622-30. doi: 10.1177/1060028015577798. Epub 2015 Mar 27.


Determination of Matrine in Rat Plasma after Oral Administration of Novel Korean Herbal Medicine KIOM-MA128 and Application of PK.

Back HM, Song B, Chae JW, Yun HY, Ma JY, Kwon KI.

J Anal Methods Chem. 2015;2015:431632. doi: 10.1155/2015/431632. Epub 2015 Feb 16.


Effects of type 2 diabetes mellitus on the population pharmacokinetics of rifampin in tuberculosis patients.

Chang MJ, Chae JW, Yun HY, Lee JI, Choi HD, Kim J, Park JS, Cho YJ, Yoon HI, Lee CT, Shin WG, Lee JH.

Tuberculosis (Edinb). 2015 Jan;95(1):54-9. doi: 10.1016/ Epub 2014 Nov 15.


Development of QTc prolongation model incorporating circadian rhythm using harmonic model.

Back HM, Lee JH, Yun HY, Kwon KI.

Xenobiotica. 2015 May;45(5):420-7. doi: 10.3109/00498254.2014.991366. Epub 2014 Dec 5.


Population pharmacogenetic pharmacokinetic modeling for flip-flop phenomenon of enteric-coated mycophenolate sodium in kidney transplant recipients.

Han N, Yun HY, Kim IW, Oh YJ, Kim YS, Oh JM.

Eur J Clin Pharmacol. 2014 Oct;70(10):1211-9. doi: 10.1007/s00228-014-1728-4. Epub 2014 Aug 28.


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