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Items: 1 to 20 of 30


Calcium-Sensing Receptor and Transient Receptor Ankyrin-1 Mediate Emesis Induction by Deoxynivalenol (Vomitoxin).

Wu W, Zhou HR, Bursian SJ, Link JE, Pestka JJ.

Toxicol Sci. 2017 Jan;155(1):32-42. doi: 10.1093/toxsci/kfw191. Epub 2016 Sep 25.


Potential roles for calcium-sensing receptor (CaSR) and transient receptor potential ankyrin-1 (TRPA1) in murine anorectic response to deoxynivalenol (vomitoxin).

Wu W, Zhou HR, Pestka JJ.

Arch Toxicol. 2017 Jan;91(1):495-507. doi: 10.1007/s00204-016-1687-x. Epub 2016 Mar 15.


Emetic responses to T-2 toxin, HT-2 toxin and emetine correspond to plasma elevations of peptide YY3-36 and 5-hydroxytryptamine.

Wu W, Zhou HR, Bursian SJ, Link JE, Pestka JJ.

Arch Toxicol. 2016 Apr;90(4):997-1007. doi: 10.1007/s00204-015-1508-7. Epub 2015 Apr 9.


Comparison of anorectic and emetic potencies of deoxynivalenol (vomitoxin) to the plant metabolite deoxynivalenol-3-glucoside and synthetic deoxynivalenol derivatives EN139528 and EN139544.

Wu W, Zhou HR, Bursian SJ, Pan X, Link JE, Berthiller F, Adam G, Krantis A, Durst T, Pestka JJ.

Toxicol Sci. 2014 Nov;142(1):167-81. doi: 10.1093/toxsci/kfu166. Epub 2014 Aug 30.


Effects of oral exposure to naturally-occurring and synthetic deoxynivalenol congeners on proinflammatory cytokine and chemokine mRNA expression in the mouse.

Wu W, He K, Zhou HR, Berthiller F, Adam G, Sugita-Konishi Y, Watanabe M, Krantis A, Durst T, Zhang H, Pestka JJ.

Toxicol Appl Pharmacol. 2014 Jul 15;278(2):107-15. doi: 10.1016/j.taap.2014.04.016. Epub 2014 Apr 29.


Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol.

Wu W, Zhou HR, He K, Pan X, Sugita-Konishi Y, Watanabe M, Zhang H, Pestka JJ.

Toxicol Sci. 2014 Apr;138(2):278-89. doi: 10.1093/toxsci/kft335. Epub 2014 Jan 2.


Peptide YY3-36 and 5-hydroxytryptamine mediate emesis induction by trichothecene deoxynivalenol (vomitoxin).

Wu W, Bates MA, Bursian SJ, Flannery B, Zhou HR, Link JE, Zhang H, Pestka JJ.

Toxicol Sci. 2013 May;133(1):186-95. doi: 10.1093/toxsci/kft033. Epub 2013 Mar 1.


Leptin differentially regulate STAT3 activation in ob/ob mouse adipose mesenchymal stem cells.

Zhou Z, Neupane M, Zhou HR, Wu D, Chang CC, Moustaid-Moussa N, Claycombe KJ.

Nutr Metab (Lond). 2012 Dec 5;9(1):109. doi: 10.1186/1743-7075-9-109.


Mechanisms for ribotoxin-induced ribosomal RNA cleavage.

He K, Zhou HR, Pestka JJ.

Toxicol Appl Pharmacol. 2012 Nov 15;265(1):10-8. doi: 10.1016/j.taap.2012.09.017. Epub 2012 Sep 27.


Modulation of inflammatory gene expression by the ribotoxin deoxynivalenol involves coordinate regulation of the transcriptome and translatome.

He K, Pan X, Zhou HR, Pestka JJ.

Toxicol Sci. 2013 Jan;131(1):153-63. doi: 10.1093/toxsci/kfs266. Epub 2012 Sep 11.


Targets and intracellular signaling mechanisms for deoxynivalenol-induced ribosomal RNA cleavage.

He K, Zhou HR, Pestka JJ.

Toxicol Sci. 2012 Jun;127(2):382-90. doi: 10.1093/toxsci/kfs134. Epub 2012 Apr 5.


Transforming growth factor beta2 is negatively regulated by endogenous retinoic acid during early heart morphogenesis.

Ghatpande SK, Zhou HR, Cakstina I, Carlson C, Rondini EA, Romeih M, Zile MH.

Dev Growth Differ. 2010 Jun;52(5):433-55. doi: 10.1111/j.1440-169X.2010.01183.x.


Obesity-associated mouse adipose stem cell secretion of monocyte chemotactic protein-1.

Zhou HR, Kim EK, Kim H, Claycombe KJ.

Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1153-8. Epub 2007 Aug 28.


Induction of competing apoptotic and survival signaling pathways in the macrophage by the ribotoxic trichothecene deoxynivalenol.

Zhou HR, Islam Z, Pestka JJ.

Toxicol Sci. 2005 Sep;87(1):113-22. Epub 2005 Jun 23.


Ribotoxic stress response to the trichothecene deoxynivalenol in the macrophage involves the SRC family kinase Hck.

Zhou HR, Jia Q, Pestka JJ.

Toxicol Sci. 2005 Jun;85(2):916-26. Epub 2005 Mar 16.


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