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Items: 1 to 20 of 62


Synthesis of NH-Sulfoximines Using Recyclable Hypervalent Iodine (III) Reagents under Aqueous Micellar Conditions.

Zhang G, Tan H, Chen W, Shen HC, Lu Y, Zheng C, Xu H.

ChemSusChem. 2020 Jan 17. doi: 10.1002/cssc.201903430. [Epub ahead of print]


Identification of viral SIM-SUMO2-interaction inhibitors for treating primary effusion lymphoma.

Ding L, Zhu Q, Zhou F, Tan H, Xu W, Pan C, Zhu C, Wang Y, Zhang H, Fu W, Qian Z, Yuan Z, Xu H, Wei F, Cai Q.

PLoS Pathog. 2019 Dec 12;15(12):e1008174. doi: 10.1371/journal.ppat.1008174. eCollection 2019 Dec.


Safranal Alleviates Dextran Sulfate Sodium-Induced Colitis and Suppresses Macrophage-Mediated Inflammation.

Lertnimitphun P, Jiang Y, Kim N, Fu W, Zheng C, Tan H, Zhou H, Zhang X, Pei W, Lu Y, Xu H.

Front Pharmacol. 2019 Nov 1;10:1281. doi: 10.3389/fphar.2019.01281. eCollection 2019.


Safety and antifatigue effect of Korean Red Ginseng: a randomized, double-blind, and placebo-controlled clinical trial.

Zhang L, Chen X, Cheng Y, Chen Q, Tan H, Son D, Chang D, Bian Z, Fang H, Xu H.

J Ginseng Res. 2019 Oct;43(4):676-683. doi: 10.1016/j.jgr.2019.05.006. Epub 2019 May 21.


Me2AlSEt-Promoted Domino Dieckmann Cyclization Enables the Total Synthesis of Polycyclic Polyprenylated Acylphloroglucinols.

Wang L, Sun L, Wang X, Wu R, Zhou H, Zheng C, Xu H.

Org Lett. 2019 Oct 4;21(19):8075-8079. doi: 10.1021/acs.orglett.9b03078. Epub 2019 Sep 24.


Andrographolide inhibits inflammatory responses in LPS-stimulated macrophages and murine acute colitis through activating AMPK.

Kim N, Lertnimitphun P, Jiang Y, Tan H, Zhou H, Lu Y, Xu H.

Biochem Pharmacol. 2019 Dec;170:113646. doi: 10.1016/j.bcp.2019.113646. Epub 2019 Sep 20.


SRC and MEK Co-inhibition Synergistically Enhances the Anti-tumor Effect in Both Non-small-cell Lung Cancer (NSCLC) and Erlotinib-Resistant NSCLC.

Yuan M, Xu LF, Zhang J, Kong SY, Wu M, Lao YZ, Zhou H, Zhang L, Xu H.

Front Oncol. 2019 Jul 30;9:586. doi: 10.3389/fonc.2019.00586. eCollection 2019.


The Natural Compound Neobractatin Induces Cell Cycle Arrest by Regulating E2F1 and Gadd45╬▒.

Zheng Z, Wu M, Zhang J, Fu W, Xu N, Lao Y, Lin L, Xu H.

Front Oncol. 2019 Jul 17;9:654. doi: 10.3389/fonc.2019.00654. eCollection 2019.


JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma.

Wong M, Sun Y, Xi Z, Milazzo G, Poulos RC, Bartenhagen C, Bell JL, Mayoh C, Ho N, Tee AE, Chen X, Li Y, Ciaccio R, Liu PY, Jiang CC, Lan Q, Jayatilleke N, Cheung BB, Haber M, Norris MD, Zhang XD, Marshall GM, Wang JY, H├╝ttelmaier S, Fischer M, Wong JWH, Xu H, Perini G, Dong Q, George RE, Liu T.

Nat Commun. 2019 Jul 25;10(1):3319. doi: 10.1038/s41467-019-11132-w.


The natural compound neobractatin inhibits tumor metastasis by upregulating the RNA-binding-protein MBNL2.

Zhang J, Zheng Z, Wu M, Zhang L, Wang J, Fu W, Xu N, Zhao Z, Lao Y, Xu H.

Cell Death Dis. 2019 Jul 18;10(8):554. doi: 10.1038/s41419-019-1789-5.


Hsp27 Responds to and Facilitates Enterovirus A71 Replication by Enhancing Viral Internal Ribosome Entry Site-Mediated Translation.

Dan X, Wan Q, Yi L, Lu J, Jiao Y, Li H, Song D, Chen Y, Xu H, He ML.

J Virol. 2019 Apr 17;93(9). pii: e02322-18. doi: 10.1128/JVI.02322-18. Print 2019 May 1.


The histone chaperone complex FACT promotes proliferative switch of G0 cancer cells.

Bi L, Xie C, Yao M, Thae Hnit SS, Vignarajan S, Wang Y, Wang Q, Xi Z, Xu H, Li Z, de Souza P, Tee A, Wong M, Liu T, Zhao X, Zhou J, Xu L, Dong Q.

Int J Cancer. 2019 Jul 1;145(1):164-178. doi: 10.1002/ijc.32065. Epub 2018 Dec 28.


Total Synthesis of Norsampsones A and B, Garcinielliptones N and O, and Hyperscabrin A.

Zheng C, Wang X, Fu W, Lu Y, Tan H, Xu H.

J Nat Prod. 2018 Nov 26;81(11):2582-2589. doi: 10.1021/acs.jnatprod.8b00763. Epub 2018 Nov 5.


Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissue.

Qiu Y, Sun Y, Xu D, Yang Y, Liu X, Wei Y, Chen Y, Feng Z, Li S, Reyad-Ul Ferdous M, Zhao Y, Xu H, Lao Y, Ding Q.

EBioMedicine. 2018 Nov;37:344-355. doi: 10.1016/j.ebiom.2018.10.019. Epub 2018 Oct 20.


Natural compound Oblongifolin C confers gemcitabine resistance in pancreatic cancer by downregulating Src/MAPK/ERK pathways.

Li Y, Xi Z, Chen X, Cai S, Liang C, Wang Z, Li Y, Tan H, Lao Y, Xu H.

Cell Death Dis. 2018 May 1;9(5):538. doi: 10.1038/s41419-018-0574-1.


Uncovering the Mechanisms of Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation by Focused Network Pharmacology Approach.

Huang T, Ning Z, Hu D, Zhang M, Zhao L, Lin C, Zhong LLD, Yang Z, Xu H, Bian Z.

Front Pharmacol. 2018 Mar 26;9:270. doi: 10.3389/fphar.2018.00270. eCollection 2018.


Gambogenic acid inhibits fibroblast growth factor receptor signaling pathway in erlotinib-resistant non-small-cell lung cancer and suppresses patient-derived xenograft growth.

Xu L, Meng X, Xu N, Fu W, Tan H, Zhang L, Zhou Q, Qian J, Tu S, Li X, Lao Y, Xu H.

Cell Death Dis. 2018 Feb 15;9(3):262. doi: 10.1038/s41419-018-0314-6.


Molecularly Imprinted Polymers for Selective Extraction of Oblongifolin C from Garcinia yunnanensis Hu.

Wang L, Fu W, Shen Y, Tan H, Xu H.

Molecules. 2017 Mar 23;22(4). pii: E508. doi: 10.3390/molecules22040508.


Natural Products Targeting EGFR Signaling Pathways as Potential Anticancer Drugs.

Wang X, Xu L, Lao Y, Zhang H, Xu H.

Curr Protein Pept Sci. 2018 Feb 13;19(4):380-388. doi: 10.2174/1389203718666170106104211. Review.


USP21 prevents the generation of T-helper-1-like Treg cells.

Li Y, Lu Y, Wang S, Han Z, Zhu F, Ni Y, Liang R, Zhang Y, Leng Q, Wei G, Shi G, Zhu R, Li D, Wang H, Zheng SG, Xu H, Tsun A, Li B.

Nat Commun. 2016 Nov 18;7:13559. doi: 10.1038/ncomms13559.

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