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Items: 14

1.

Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis.

Huang M, Tailor J, Zhen Q, Gillmor AH, Miller ML, Weishaupt H, Chen J, Zheng T, Nash EK, McHenry LK, An Z, Ye F, Takashima Y, Clarke J, Ayetey H, Cavalli FMG, Luu B, Moriarity BS, Ilkhanizadeh S, Chavez L, Yu C, Kurian KM, Magnaldo T, Sevenet N, Koch P, Pollard SM, Dirks P, Snyder MP, Largaespada DA, Cho YJ, Phillips JJ, Swartling FJ, Morrissy AS, Kool M, Pfister SM, Taylor MD, Smith A, Weiss WA.

Cell Stem Cell. 2019 Sep 5;25(3):433-446.e7. doi: 10.1016/j.stem.2019.05.013. Epub 2019 Jun 13.

2.

Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes.

Weishaupt H, Johansson P, Sundström A, Lubovac-Pilav Z, Olsson B, Nelander S, Swartling FJ.

Bioinformatics. 2019 Sep 15;35(18):3357-3364. doi: 10.1093/bioinformatics/btz066.

PMID:
30715209
3.

Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma.

Bolin S, Borgenvik A, Persson CU, Sundström A, Qi J, Bradner JE, Weiss WA, Cho YJ, Weishaupt H, Swartling FJ.

Oncogene. 2018 May;37(21):2850-2862. doi: 10.1038/s41388-018-0135-1. Epub 2018 Mar 7.

4.

Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential.

Roy A, Libard S, Weishaupt H, Gustavsson I, Uhrbom L, Hesselager G, Swartling FJ, Pontén F, Alafuzoff I, Tchougounova E.

Front Oncol. 2017 Jun 2;7:115. doi: 10.3389/fonc.2017.00115. eCollection 2017.

5.

Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression.

Roy A, Attarha S, Weishaupt H, Edqvist PH, Swartling FJ, Bergqvist M, Siebzehnrubl FA, Smits A, Pontén F, Tchougounova E.

Oncotarget. 2017 Apr 11;8(15):24815-24827. doi: 10.18632/oncotarget.15820.

6.

Modeling and Targeting MYC Genes in Childhood Brain Tumors.

Hutter S, Bolin S, Weishaupt H, Swartling FJ.

Genes (Basel). 2017 Mar 23;8(4). pii: E107. doi: 10.3390/genes8040107. Review.

7.

Mouse Models of Pediatric Supratentorial High-grade Glioma Reveal How Cell-of-Origin Influences Tumor Development and Phenotype.

Sreedharan S, Maturi NP, Xie Y, Sundström A, Jarvius M, Libard S, Alafuzoff I, Weishaupt H, Fryknäs M, Larsson R, Swartling FJ, Uhrbom L.

Cancer Res. 2017 Feb 1;77(3):802-812. doi: 10.1158/0008-5472.CAN-16-2482. Epub 2016 Nov 15.

8.

FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma.

Suryo Rahmanto A, Savov V, Brunner A, Bolin S, Weishaupt H, Malyukova A, Rosén G, Čančer M, Hutter S, Sundström A, Kawauchi D, Jones DT, Spruck C, Taylor MD, Cho YJ, Pfister SM, Kool M, Korshunov A, Swartling FJ, Sangfelt O.

EMBO J. 2016 Oct 17;35(20):2192-2212. Epub 2016 Sep 13.

9.

Utilizing the Dog Genome in the Search for Novel Candidate Genes Involved in Glioma Development-Genome Wide Association Mapping followed by Targeted Massive Parallel Sequencing Identifies a Strongly Associated Locus.

Truvé K, Dickinson P, Xiong A, York D, Jayashankar K, Pielberg G, Koltookian M, Murén E, Fuxelius HH, Weishaupt H, Swartling FJ, Andersson G, Hedhammar Å, Bongcam-Rudloff E, Forsberg-Nilsson K, Bannasch D, Lindblad-Toh K.

PLoS Genet. 2016 May 12;12(5):e1006000. doi: 10.1371/journal.pgen.1006000. eCollection 2016 May.

10.

Context-Dependent Development of Lymphoid Stroma from Adult CD34(+) Adventitial Progenitors.

Sitnik KM, Wendland K, Weishaupt H, Uronen-Hansson H, White AJ, Anderson G, Kotarsky K, Agace WW.

Cell Rep. 2016 Mar 15;14(10):2375-88. doi: 10.1016/j.celrep.2016.02.033. Epub 2016 Mar 3.

11.

Deregulated proliferation and differentiation in brain tumors.

Swartling FJ, Čančer M, Frantz A, Weishaupt H, Persson AI.

Cell Tissue Res. 2015 Jan;359(1):225-54. doi: 10.1007/s00441-014-2046-y. Epub 2014 Nov 23. Review.

12.

Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes.

Nitert MD, Dayeh T, Volkov P, Elgzyri T, Hall E, Nilsson E, Yang BT, Lang S, Parikh H, Wessman Y, Weishaupt H, Attema J, Abels M, Wierup N, Almgren P, Jansson PA, Rönn T, Hansson O, Eriksson KF, Groop L, Ling C.

Diabetes. 2012 Dec;61(12):3322-32. doi: 10.2337/db11-1653. Epub 2012 Oct 1.

13.

A Method to Study the Epigenetic Chromatin States of Rare Hematopoietic Stem and Progenitor Cells; MiniChIP-Chip.

Weishaupt H, Attema JL.

Biol Proced Online. 2010 May 15;12(1):1-17. doi: 10.1007/s12575-010-9031-y.

14.

Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells.

Weishaupt H, Sigvardsson M, Attema JL.

Blood. 2010 Jan 14;115(2):247-56. doi: 10.1182/blood-2009-07-235176. Epub 2009 Nov 3.

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