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Items: 1 to 20 of 36


Cellular interactions between L-arginine and asymmetric dimethylarginine: Transport and metabolism.

Shin S, Thapa SK, Fung HL.

PLoS One. 2017 May 31;12(5):e0178710. doi: 10.1371/journal.pone.0178710. eCollection 2017.


Perspectives on the history and scientific contributions of Gerhard Levy.

Fung HL, Jusko WJ.

J Pharmacokinet Pharmacodyn. 2015 Oct;42(5):429-46. doi: 10.1007/s10928-015-9442-0. Epub 2015 Sep 24. No abstract available.


Preface to the special issue to honor Gerhard Levy and 50 years of PK/PD.

Jusko WJ, Fung HL.

J Pharmacokinet Pharmacodyn. 2015 Oct;42(5):427. doi: 10.1007/s10928-015-9443-z. No abstract available.


Estimation of nitric oxide synthase activity via liquid chromatography/tandem mass spectrometric assay determination of 15N3 -citrulline in biological samples.

Shin BS, Fung HL, Upadhyay M, Shin S.

Rapid Commun Mass Spectrom. 2015 Mar 15;29(5):447-55. doi: 10.1002/rcm.7124.


In vitro organic nitrate bioactivation to nitric oxide by recombinant aldehyde dehydrogenase 3A1.

Lin S, Page NA, Fung SM, Fung HL.

Nitric Oxide. 2013 Nov 30;35:137-43. doi: 10.1016/j.niox.2013.09.005. Epub 2013 Oct 11.


Organic nitrate metabolism and action: toward a unifying hypothesis and the future-a dedication to Professor Leslie Z. Benet.

Page NA, Fung HL.

J Pharm Sci. 2013 Sep;102(9):3070-81. doi: 10.1002/jps.23550. Epub 2013 May 13. Review.


Mechanism of cellular oxidation stress induced by asymmetric dimethylarginine.

Mohan S, Fung HL.

Int J Mol Sci. 2012;13(6):7521-31. doi: 10.3390/ijms13067521. Epub 2012 Jun 18.


Continuous exposure to L-arginine induces oxidative stress and physiological tolerance in cultured human endothelial cells.

Mohan S, Wu CC, Shin S, Fung HL.

Amino Acids. 2012 Sep;43(3):1179-88. doi: 10.1007/s00726-011-1173-y. Epub 2011 Dec 1.


Intracellular L-arginine concentration does not determine NO production in endothelial cells: implications on the "L-arginine paradox".

Shin S, Mohan S, Fung HL.

Biochem Biophys Res Commun. 2011 Nov 4;414(4):660-3. doi: 10.1016/j.bbrc.2011.09.112. Epub 2011 Oct 1.


Evaluation of an LC-MS/MS assay for 15N-nitrite for cellular studies of L-arginine action.

Shin S, Fung HL.

J Pharm Biomed Anal. 2011 Dec 15;56(5):1127-31. doi: 10.1016/j.jpba.2011.08.017. Epub 2011 Aug 12.


Differential metabolism of organic nitrates by aldehyde dehydrogenase 1a1 and 2: substrate selectivity, enzyme inactivation, and active cysteine sites.

Tsou PS, Page NA, Lee SG, Fung SM, Keung WM, Fung HL.

AAPS J. 2011 Dec;13(4):548-55. doi: 10.1208/s12248-011-9295-4. Epub 2011 Aug 5.


Identification of nitroglycerin-induced cysteine modifications of pro-matrix metalloproteinase-9.

Krishnatry AS, Kamei T, Wang H, Qu J, Fung HL.

Rapid Commun Mass Spectrom. 2011 Aug 30;25(16):2291-8. doi: 10.1002/rcm.5118.


Editorial: a new series of commentaries entitled "Landmark publications in the pharmaceutical sciences: the backstory".

Fung HL.

AAPS J. 2011 Sep;13(3):319. doi: 10.1208/s12248-011-9278-5. Epub 2011 May 21. No abstract available.


Simultaneous bioanalysis of L-arginine, L-citrulline, and dimethylarginines by LC-MS/MS.

Shin S, Fung SM, Mohan S, Fung HL.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Mar 1;879(7-8):467-74. doi: 10.1016/j.jchromb.2011.01.006. Epub 2011 Jan 14.


Nitroglycerin alters matrix remodeling proteins in THP-1 human macrophages and plasma metalloproteinase activity in rats.

Krishnatry AS, Fung SM, Brazeau DA, Soda D, Fung HL.

Nitric Oxide. 2011 Mar 15;24(2):66-76. doi: 10.1016/j.niox.2010.12.002. Epub 2010 Dec 13.


Broad regulation of matrix and adhesion molecules in THP-1 human macrophages by nitroglycerin.

Krishnatry AS, Brazeau DA, Fung HL.

Nitric Oxide. 2010 Jan 1;22(1):11-7. doi: 10.1016/j.niox.2009.10.004. Epub 2009 Oct 15.


Role of glutaredoxin-mediated protein S-glutathionylation in cellular nitroglycerin tolerance.

Tsou PS, Addanki V, Haas JA, Page NA, Fung HL.

J Pharmacol Exp Ther. 2009 May;329(2):649-56. doi: 10.1124/jpet.108.149997. Epub 2009 Feb 17.


Dissociation between superoxide accumulation and nitroglycerin-induced tolerance.

Tsou PS, Addanki V, Fung HL.

J Pharmacol Exp Ther. 2008 Oct;327(1):97-104. doi: 10.1124/jpet.108.138784. Epub 2008 Jul 24.


Pharmacokinetics of 1,4-butanediol in rats: bioactivation to gamma-hydroxybutyric acid, interaction with ethanol, and oral bioavailability.

Fung HL, Tsou PS, Bulitta JB, Tran DC, Page NA, Soda D, Mi Fung S.

AAPS J. 2008;10(1):56-69. doi: 10.1208/s12248-007-9006-3. Epub 2008 Feb 8.


Effects of inhalant nitrites on VEGF expression: a feasible link to Kaposi's sarcoma?

Fung HL, Tran DC.

J Neuroimmune Pharmacol. 2006 Sep;1(3):317-22. Review.


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