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Items: 1 to 20 of 46


The concept of the okadaic acid class of tumor promoters is revived in endogenous protein inhibitors of protein phosphatase 2A, SET and CIP2A, in human cancers.

Fujiki H, Sueoka E, Watanabe T, Suganuma M.

J Cancer Res Clin Oncol. 2018 Dec;144(12):2339-2349. doi: 10.1007/s00432-018-2765-7. Epub 2018 Oct 20. Review.


Green Tea Catechin Is an Alternative Immune Checkpoint Inhibitor that Inhibits PD-L1 Expression and Lung Tumor Growth.

Rawangkan A, Wongsirisin P, Namiki K, Iida K, Kobayashi Y, Shimizu Y, Fujiki H, Suganuma M.

Molecules. 2018 Aug 18;23(8). pii: E2071. doi: 10.3390/molecules23082071.


Cancer Prevention with Green Tea and Its Principal Constituent, EGCG: from Early Investigations to Current Focus on Human Cancer Stem Cells.

Fujiki H, Watanabe T, Sueoka E, Rawangkan A, Suganuma M.

Mol Cells. 2018 Feb 28;41(2):73-82. doi: 10.14348/molcells.2018.2227. Epub 2018 Jan 31. Review.


Human cancer stem cells are a target for cancer prevention using (-)-epigallocatechin gallate.

Fujiki H, Sueoka E, Rawangkan A, Suganuma M.

J Cancer Res Clin Oncol. 2017 Dec;143(12):2401-2412. doi: 10.1007/s00432-017-2515-2. Epub 2017 Sep 23. Review.


Phorbol esters in seed oil of Jatropha curcas L. (saboodam in Thai) and their association with cancer prevention: from the initial investigation to the present topics.

Fujiki H, Suttajit M, Rawangkan A, Iida K, Limtrakul P, Umsumarng S, Suganuma M.

J Cancer Res Clin Oncol. 2017 Aug;143(8):1359-1369. doi: 10.1007/s00432-017-2341-6. Epub 2017 Jan 25. Review.


Down-regulation of histone deacetylase 4, -5 and -6 as a mechanism of synergistic enhancement of apoptosis in human lung cancer cells treated with the combination of a synthetic retinoid, Am80 and green tea catechin.

Oya Y, Mondal A, Rawangkan A, Umsumarng S, Iida K, Watanabe T, Kanno M, Suzuki K, Li Z, Kagechika H, Shudo K, Fujiki H, Suganuma M.

J Nutr Biochem. 2017 Apr;42:7-16. doi: 10.1016/j.jnutbio.2016.12.015. Epub 2017 Jan 8.


Biophysical Approach to Mechanisms of Cancer Prevention and Treatment with Green Tea Catechins.

Suganuma M, Takahashi A, Watanabe T, Iida K, Matsuzaki T, Yoshikawa HY, Fujiki H.

Molecules. 2016 Nov 18;21(11). pii: E1566. Review.


Primary cancer prevention by green tea, and tertiary cancer prevention by the combination of green tea catechins and anticancer compounds.

Fujiki H, Sueoka E, Watanabe T, Suganuma M.

J Cancer Prev. 2015 Mar;20(1):1-4. doi: 10.15430/JCP.2015.20.1.1. Review.


Synergistic enhancement of anticancer effects on numerous human cancer cell lines treated with the combination of EGCG, other green tea catechins, and anticancer compounds.

Fujiki H, Sueoka E, Watanabe T, Suganuma M.

J Cancer Res Clin Oncol. 2015 Sep;141(9):1511-22. doi: 10.1007/s00432-014-1899-5. Epub 2014 Dec 28. Review.


Cell-surface nucleolin acts as a central mediator for carcinogenic, anti-carcinogenic, and disease-related ligands.

Fujiki H, Watanabe T, Suganuma M.

J Cancer Res Clin Oncol. 2014 May;140(5):689-99. doi: 10.1007/s00432-014-1587-5. Epub 2014 Jan 28.


Gist of Dr. Katsusaburo Yamagiwa's papers entitled "Experimental study on the pathogenesis of epithelial tumors" (I to VI reports).

Fujiki H.

Cancer Sci. 2014 Feb;105(2):143-9. doi: 10.1111/cas.12333. Epub 2014 Jan 17. Review.


Mechanism-based inhibition of cancer metastasis with (-)-epigallocatechin gallate.

Takahashi A, Watanabe T, Mondal A, Suzuki K, Kurusu-Kanno M, Li Z, Yamazaki T, Fujiki H, Suganuma M.

Biochem Biophys Res Commun. 2014 Jan 3;443(1):1-6. doi: 10.1016/j.bbrc.2013.10.094. Epub 2013 Nov 21.


Epithelial-mesenchymal transition in human gastric cancer cell lines induced by TNF-α-inducing protein of Helicobacter pylori.

Watanabe T, Takahashi A, Suzuki K, Kurusu-Kanno M, Yamaguchi K, Fujiki H, Suganuma M.

Int J Cancer. 2014 May 15;134(10):2373-82. doi: 10.1002/ijc.28582. Epub 2013 Nov 19.


Tumor promoters: from chemicals to inflammatory proteins.

Fujiki H, Sueoka E, Suganuma M.

J Cancer Res Clin Oncol. 2013 Oct;139(10):1603-14. doi: 10.1007/s00432-013-1455-8. Epub 2013 Jun 12. Review.


The eleventh Korea-Japan-Germany joint symposium on cancer and ageing research.

Kim EG, Seimiya H, Chung J, Hoheisel J, Lim IK, Fujiki H, Park SC.

J Cancer Res Clin Oncol. 2013 Jun;139(6):901-4. doi: 10.1007/s00432-013-1397-1. Epub 2013 Feb 28. No abstract available.


Challenging the effectiveness of green tea in primary and tertiary cancer prevention.

Fujiki H, Imai K, Nakachi K, Shimizu M, Moriwaki H, Suganuma M.

J Cancer Res Clin Oncol. 2012 Aug;138(8):1259-70. doi: 10.1007/s00432-012-1250-y. Epub 2012 Jun 15. Review.


Green tea: an effective synergist with anticancer drugs for tertiary cancer prevention.

Fujiki H, Suganuma M.

Cancer Lett. 2012 Nov 28;324(2):119-25. doi: 10.1016/j.canlet.2012.05.012. Epub 2012 May 21. Review.


Human gastric cancer development with TNF-α-inducing protein secreted from Helicobacter pylori.

Suganuma M, Watanabe T, Yamaguchi K, Takahashi A, Fujiki H.

Cancer Lett. 2012 Sep 28;322(2):133-8. doi: 10.1016/j.canlet.2012.03.027. Epub 2012 Mar 27. Review.


Higher cell stiffness indicating lower metastatic potential in B16 melanoma cell variants and in (-)-epigallocatechin gallate-treated cells.

Watanabe T, Kuramochi H, Takahashi A, Imai K, Katsuta N, Nakayama T, Fujiki H, Suganuma M.

J Cancer Res Clin Oncol. 2012 May;138(5):859-66. doi: 10.1007/s00432-012-1159-5.


Tumor promoters--microcystin-LR, nodularin and TNF-α and human cancer development.

Fujiki H, Suganuma M.

Anticancer Agents Med Chem. 2011 Jan;11(1):4-18. Review.


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