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Items: 1 to 20 of 449

1.

Cloning and tissue expression of cytochrome P450 2S1, 4V2, 7A1, 7B1, 8B1, 24A1, 26A1, 26C1, 27A1, 39A1, and 51A1 in marmosets.

Uehara S, Uno Y, Inoue T, Sasaki E, Yamazaki H.

Drug Metab Pharmacokinet. 2019 Dec 26. pii: S1347-4367(19)30240-X. doi: 10.1016/j.dmpk.2019.11.008. [Epub ahead of print]

PMID:
31980379
2.

mRNA levels of drug-metabolizing enzymes in 11 brain regions of cynomolgus macaques.

Uno Y, Yamazaki H.

Drug Metab Pharmacokinet. 2019 Dec 31. pii: S1347-4367(19)30243-5. doi: 10.1016/j.dmpk.2019.12.003. [Epub ahead of print]

PMID:
31964621
3.

Plasma concentrations of pemafibrate with co-administered drugs predicted by physiologically based pharmacokinetic modeling in virtual populations with renal/hepatic impairment.

Ogawa SI, Shimizu M, Yamazaki H.

Xenobiotica. 2020 Jan 3:1-9. doi: 10.1080/00498254.2019.1709133. [Epub ahead of print]

PMID:
31900032
4.

Different Roles of Human Cytochrome P450 2C9 and 3A Enzymes in Diclofenac 4'- and 5-Hydroxylations Mediated by Metabolically Inactivated Human Hepatocytes in Previously Transplanted Chimeric Mice.

Miura T, Uehara S, Shimizu M, Murayama N, Utoh M, Suemizu H, Yamazaki H.

Chem Res Toxicol. 2019 Dec 31. doi: 10.1021/acs.chemrestox.9b00446. [Epub ahead of print]

PMID:
31854189
5.

Interhemispheric auditory connectivity requires normal access to sound in both ears during development.

Smieja DA, Dunkley BT, Papsin BC, Easwar V, Yamazaki H, Deighton M, Gordon KA.

Neuroimage. 2019 Dec 10;208:116455. doi: 10.1016/j.neuroimage.2019.116455. [Epub ahead of print]

6.

Molecular characterization of functional UDP-glucuronosyltransferases 1A and 2B in common marmosets.

Uno Y, Uehara S, Inoue T, Kawamura S, Murayama N, Nishikawa M, Ikushiro S, Sasaki E, Yamazaki H.

Biochem Pharmacol. 2020 Feb;172:113748. doi: 10.1016/j.bcp.2019.113748. Epub 2019 Dec 10.

PMID:
31830470
7.

Efficacy of apheresis as maintenance therapy for patients with ulcerative colitis in an open-label prospective multicenter randomised controlled trial.

Naganuma M, Yokoyama Y, Motoya S, Watanabe K, Sawada K, Hirai F, Yamamoto T, Hanai H, Omori T, Kanai T, Hibi T; CAPTAIN study Group.

J Gastroenterol. 2019 Dec 6. doi: 10.1007/s00535-019-01651-0. [Epub ahead of print]

PMID:
31811562
8.

Prediction of circulating human metabolites of pemafibrate, a novel antidyslipidemic drug, using chimeric mice with humanized liver.

Ogawa SI, Uehara S, Tsunenari Y, Kawai H, Suemizu H, Yamazaki H.

Xenobiotica. 2019 Nov 25:1-7. doi: 10.1080/00498254.2019.1694198. [Epub ahead of print]

PMID:
31766940
9.

The marmoset cytochrome P450 superfamily: Sequence/phylogenetic analyses, genomic structure, and catalytic function.

Uehara S, Uno Y, Yamazaki H.

Biochem Pharmacol. 2020 Jan;171:113721. doi: 10.1016/j.bcp.2019.113721. Epub 2019 Nov 18. Review.

PMID:
31751534
10.

Adult and infant pharmacokinetic profiling of dihydrocodeine using physiologically based pharmacokinetic modeling.

Ota M, Shimizu M, Kamiya Y, Emoto C, Fukuda T, Yamazaki H.

Biopharm Drug Dispos. 2019 Nov;40(9):350-357. doi: 10.1002/bdd.2209. Epub 2019 Nov 21.

PMID:
31691978
11.

Prospective Evaluation of Median Nerve Dysfunctions in Patients with a Distal Radius Fracture Treated with Volar Locking Plating.

Isobe F, Yamazaki H, Hayashi M, Uchiyama S, Miyaoka S, Kato H.

J Hand Surg Asian Pac Vol. 2019 Dec;24(4):392-399. doi: 10.1142/S2424835519500498.

PMID:
31690191
12.

Metabolism of desloratadine by chimeric TK-NOG mice transplanted with human hepatocytes.

Uehara S, Yoneda N, Higuchi Y, Yamazaki H, Suemizu H.

Xenobiotica. 2019 Nov 12:1-8. doi: 10.1080/00498254.2019.1688892. [Epub ahead of print]

PMID:
31690163
13.

Expression levels of microRNAs that are potential cytochrome P450 regulators in cynomolgus macaques.

Uno Y, Yamazaki H.

Xenobiotica. 2019 Nov 11:1-6. doi: 10.1080/00498254.2019.1688423. [Epub ahead of print]

PMID:
31682544
14.

Radiographic Change in Articular Reduction After Volar Locking Plating for Intra-Articular Distal Radius Fractures.

Hashimoto S, Yamazaki H, Hayashi M, Isobe F, Miyaoka S, Kitamura Y, Kato H.

J Hand Surg Am. 2019 Oct 24. pii: S0363-5023(18)30864-5. doi: 10.1016/j.jhsa.2019.08.012. [Epub ahead of print]

PMID:
31668645
15.

Extrapolation of Hepatic Concentrations of Industrial Chemicals Using Pharmacokinetic Models to Predict Hepatotoxicity.

Yamazaki H, Kamiya Y.

Toxicol Res. 2019 Oct;35(4):295-301. doi: 10.5487/TR.2019.35.4.295. Epub 2019 Oct 15. Review.

16.

Net-400-Gbps PS-PAM transmission using integrated AMUX-MZM.

Yamazaki H, Nakamura M, Kobayashi T, Nagatani M, Wakita H, Ogiso Y, Nosaka H, Hashimoto T, Miyamoto Y.

Opt Express. 2019 Sep 2;27(18):25544-25550. doi: 10.1364/OE.27.025544.

PMID:
31510425
17.
18.

Defect repair with fibrin glue/polyglycolic acid after endoscopic laryngopharyngeal cancer resection.

Watanabe Y, Tanaka S, Hiratsuka Y, Yamazaki H, Yoshida T, Kusano J, Matsunaga M, Kitano M, Nakahira M, Oe K.

Laryngoscope. 2019 Aug 28. doi: 10.1002/lary.28265. [Epub ahead of print]

PMID:
31461175
19.

Altered DNA methylation is associated with aberrant stemness gene expression in early‑stage HNSCC.

Suzuki T, Yamazaki H, Honda K, Ryo E, Kaneko A, Ota Y, Mori T.

Int J Oncol. 2019 Oct;55(4):915-924. doi: 10.3892/ijo.2019.4857. Epub 2019 Aug 14.

PMID:
31432153
20.

Genetic variants of flavin-containing monooxygenase 3 (FMO3) derived from Japanese subjects with the trimethylaminuria phenotype and whole-genome sequence data from a large Japanese database.

Shimizu M, Yoda H, Nakakuki K, Saso A, Saito I, Hishinuma E, Saito S, Hiratsuka M, Yamazaki H.

Drug Metab Pharmacokinet. 2019 Oct;34(5):334-339. doi: 10.1016/j.dmpk.2019.06.001. Epub 2019 Jun 27.

PMID:
31401033

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