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Items: 1 to 20 of 35

1.

Design of Synthetic Polymer Nanoparticles Specifically Capturing Indole, a Small Toxic Molecule.

Okishima A, Koide H, Hoshino Y, Egami H, Hamashima Y, Oku N, Asai T.

Biomacromolecules. 2019 Apr 8;20(4):1644-1654. doi: 10.1021/acs.biomac.8b01820. Epub 2019 Mar 15.

PMID:
30848887
2.

Rigorous control of vesicle-forming lipid pKa by fluorine-conjugated bioisosteres for gene-silencing with siRNA.

Okamoto A, Koide H, Morita N, Hirai Y, Kawato Y, Egami H, Hamashima Y, Asai T, Dewa T, Oku N.

J Control Release. 2019 Feb 10;295:87-92. doi: 10.1016/j.jconrel.2018.12.044. Epub 2018 Dec 26.

PMID:
30593831
3.

Sequestering and inhibiting a vascular endothelial growth factor in vivo by systemic administration of a synthetic polymer nanoparticle.

Koide H, Yoshimatsu K, Hoshino Y, Ariizumi S, Okishima A, Ide T, Egami H, Hamashima Y, Nishimura Y, Kanazawa H, Miura Y, Asai T, Oku N, Shea KJ.

J Control Release. 2019 Feb 10;295:13-20. doi: 10.1016/j.jconrel.2018.12.033. Epub 2018 Dec 20.

PMID:
30578808
4.

Regio- and chemoselective Csp3-H arylation of benzylamines by single electron transfer/hydrogen atom transfer synergistic catalysis.

Ide T, Barham JP, Fujita M, Kawato Y, Egami H, Hamashima Y.

Chem Sci. 2018 Sep 12;9(44):8453-8460. doi: 10.1039/c8sc02965b. eCollection 2018 Nov 28.

5.

Practical and Scalable Organic Reactions with Flow Microwave Apparatus.

Egami H, Hamashima Y.

Chem Rec. 2019 Jan;19(1):157-171. doi: 10.1002/tcr.201800132. Epub 2018 Dec 4. Review.

PMID:
30511806
6.

C-Alkylation of N-alkylamides with styrenes in air and scale-up using a microwave flow reactor.

Barham JP, Tamaoki S, Egami H, Ohneda N, Okamoto T, Odajima H, Hamashima Y.

Org Biomol Chem. 2018 Nov 7;16(41):7568-7573. doi: 10.1039/c8ob02282h. Epub 2018 Oct 9.

PMID:
30298895
7.

Asymmetric Fluorination of Cyclic Tetrasubstituted Alkenes with a Pendant Amide Groups under Dianionic Phase-Transfer Catalysis.

Niwa T, Ujiie K, Sato H, Egami H, Hamashima Y.

Chem Pharm Bull (Tokyo). 2018;66(10):920-922. doi: 10.1248/cpb.c18-00551.

8.

Enantioselective Synthesis of Nelfinavir via Asymmetric Bromocyclization of Bisallylic Amide.

Nagao Y, Hisanaga T, Utsumi T, Egami H, Kawato Y, Hamashima Y.

J Org Chem. 2018 Jul 6;83(13):7290-7295. doi: 10.1021/acs.joc.8b00039. Epub 2018 Mar 1.

PMID:
29480721
9.

Photofluorination of Aliphatic C-H Bonds Promoted by the Phthalimide Group.

Egami H, Masuda S, Kawato Y, Hamashima Y.

Org Lett. 2018 Mar 2;20(5):1367-1370. doi: 10.1021/acs.orglett.8b00133. Epub 2018 Feb 14.

PMID:
29442520
10.

Dianionic Phase-Transfer Catalyst for Asymmetric Fluoro-cyclization.

Egami H, Niwa T, Sato H, Hotta R, Rouno D, Kawato Y, Hamashima Y.

J Am Chem Soc. 2018 Feb 28;140(8):2785-2788. doi: 10.1021/jacs.7b13690. Epub 2018 Feb 12.

PMID:
29424534
11.

Desymmetrization of Bisallylic Amides through Catalytic Enantioselective Bromocyclization with BINAP Monoxide.

Nagao Y, Hisanaga T, Egami H, Kawato Y, Hamashima Y.

Chemistry. 2017 Nov 27;23(66):16758-16762. doi: 10.1002/chem.201704847. Epub 2017 Nov 6.

PMID:
29044749
12.

Benzylic C-H Trifluoromethylation via Photoenol.

Ide T, Masuda S, Kawato Y, Egami H, Hamashima Y.

Org Lett. 2017 Sep 1;19(17):4452-4455. doi: 10.1021/acs.orglett.7b01971. Epub 2017 Aug 11.

PMID:
28799765
13.

Difunctionalization of Alkenes Using 1-Chloro-1,2-benziodoxol-3-(1H)-one.

Egami H, Yoneda T, Uku M, Ide T, Kawato Y, Hamashima Y.

J Org Chem. 2016 May 20;81(10):4020-30. doi: 10.1021/acs.joc.6b00295. Epub 2016 Apr 28.

PMID:
27100051
14.

Highly Enantioselective Bromocyclization of Allylic Amides with a P/P=O Double-Site Lewis Base Catalyst.

Kawato Y, Ono H, Kubota A, Nagao Y, Morita N, Egami H, Hamashima Y.

Chemistry. 2016 Feb;22(6):2127-2133. doi: 10.1002/chem.201503153. Epub 2016 Jan 7.

PMID:
26743540
15.

Benzylic C-H trifluoromethylation of phenol derivatives.

Egami H, Ide T, Kawato Y, Hamashima Y.

Chem Commun (Camb). 2015 Dec 4;51(93):16675-8. doi: 10.1039/c5cc07011b. Epub 2015 Oct 2.

PMID:
26431449
16.

Asymmetric Fluorolactonization with a Bifunctional Hydroxyl Carboxylate Catalyst.

Egami H, Asada J, Sato K, Hashizume D, Kawato Y, Hamashima Y.

J Am Chem Soc. 2015 Aug 19;137(32):10132-5. doi: 10.1021/jacs.5b06546. Epub 2015 Aug 10.

PMID:
26251311
17.

Product Control in Alkene Trifluoromethylation: Hydrotrifluoromethylation, Vinylic Trifluoromethylation, and Iodotrifluoromethylation using Togni Reagent.

Egami H, Usui Y, Kawamura S, Nagashima S, Sodeoka M.

Chem Asian J. 2015 Oct;10(10):2190-9. doi: 10.1002/asia.201500359. Epub 2015 Jun 16.

18.

Aminotrifluoromethylation of olefins via cyclic amine formation: mechanistic study and application to synthesis of trifluoromethylated pyrrolidines.

Kawamura S, Egami H, Sodeoka M.

J Am Chem Soc. 2015 Apr 15;137(14):4865-73. doi: 10.1021/jacs.5b02046. Epub 2015 Apr 1.

PMID:
25798656
19.

Enantioselective bromocyclization of allylic amides catalyzed by BINAP derivatives.

Kawato Y, Kubota A, Ono H, Egami H, Hamashima Y.

Org Lett. 2015 Mar 6;17(5):1244-7. doi: 10.1021/acs.orglett.5b00220. Epub 2015 Feb 20.

PMID:
25699577
20.

Dual catalysis with copper and rhenium for trifluoromethylation of propargylic alcohols: efficient synthesis of α-trifluoromethylated enones.

Egami H, Ide T, Fujita M, Tojo T, Hamashima Y, Sodeoka M.

Chemistry. 2014 Sep 15;20(38):12061-5. doi: 10.1002/chem.201403447. Epub 2014 Jul 30.

PMID:
25077456

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