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Items: 1 to 20 of 121

1.

Protein O-glucosylation: another essential role of glucose in biology.

Yu H, Takeuchi H.

Curr Opin Struct Biol. 2019 Jan 18;56:64-71. doi: 10.1016/j.sbi.2018.12.001. [Epub ahead of print] Review.

PMID:
30665188
2.

Microglia in Alzheimer's Disease: Risk Factors and Inflammation.

Katsumoto A, Takeuchi H, Takahashi K, Tanaka F.

Front Neurol. 2018 Nov 15;9:978. doi: 10.3389/fneur.2018.00978. eCollection 2018. Review.

3.

Altered Notch Signaling in Dowling-Degos Disease: Additional Mutations in POGLUT1 and Further Insights into Disease Pathogenesis.

Ralser DJ, Takeuchi H, Fritz G, Basmanav FB, Effern M, Sivalingam S, El-Shabrawi-Caelen L, Degirmentepe EN, Kocatürk E, Singh M, Booken N, Spierings NMK, Schnabel V, Heineke A, Knuever J, Wolf S, Wehner M, Tronnier M, Leverkus M, Tantcheva-Poór I, Wenzel J, Oji V, Has C, Hölzel M, Frank J, Haltiwanger RS, Betz RC.

J Invest Dermatol. 2018 Nov 9. pii: S0022-202X(18)32800-8. doi: 10.1016/j.jid.2018.10.030. [Epub ahead of print] No abstract available.

PMID:
30414910
4.

Biallelic COLGALT1 variants are associated with cerebral small vessel disease.

Miyatake S, Schneeberger S, Koyama N, Yokochi K, Ohmura K, Shiina M, Mori H, Koshimizu E, Imagawa E, Uchiyama Y, Mitsuhashi S, Frith MC, Fujita A, Satoh M, Taguri M, Tomono Y, Takahashi K, Doi H, Takeuchi H, Nakashima M, Mizuguchi T, Takata A, Miyake N, Saitsu H, Tanaka F, Ogata K, Hennet T, Matsumoto N.

Ann Neurol. 2018 Dec;84(6):843-853. doi: 10.1002/ana.25367. Epub 2018 Nov 30.

PMID:
30412317
5.

Two novel protein O-glucosyltransferases that modify sites distinct from POGLUT1 and affect Notch trafficking and signaling.

Takeuchi H, Schneider M, Williamson DB, Ito A, Takeuchi M, Handford PA, Haltiwanger RS.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8395-E8402. doi: 10.1073/pnas.1804005115. Epub 2018 Aug 20.

PMID:
30127001
6.

Structural Divergence in O-GlcNAc Glycans Displayed on Epidermal Growth Factor-like Repeats of Mammalian Notch1.

Ogawa M, Senoo Y, Ikeda K, Takeuchi H, Okajima T.

Molecules. 2018 Jul 17;23(7). pii: E1745. doi: 10.3390/molecules23071745.

7.

Metformin treatment ameliorates diabetes-associated decline in hippocampal neurogenesis and memory via phosphorylation of insulin receptor substrate 1.

Tanokashira D, Kurata E, Fukuokaya W, Kawabe K, Kashiwada M, Takeuchi H, Nakazato M, Taguchi A.

FEBS Open Bio. 2018 May 18;8(7):1104-1118. doi: 10.1002/2211-5463.12436. eCollection 2018 Jul. Erratum in: FEBS Open Bio. 2018 Oct 22;8(11):1882-1883.

8.

A central-acting connexin inhibitor, INI-0602, prevents high-fat diet-induced feeding pattern disturbances and obesity in mice.

Sasaki T, Numano R, Yokota-Hashimoto H, Matsui S, Kimura N, Takeuchi H, Kitamura T.

Mol Brain. 2018 May 24;11(1):28. doi: 10.1186/s13041-018-0372-9.

9.

Two cases of anaphylactic shock by methylprednisolone in neuromyelitis optica.

Takahashi K, Asano T, Higashiyama Y, Koyano S, Doi H, Takeuchi H, Tanaka F.

Mult Scler. 2018 Oct;24(11):1514-1516. doi: 10.1177/1352458518763099. Epub 2018 Apr 19.

PMID:
29671689
10.

A Critical Domain of Ebolavirus Envelope Glycoprotein Determines Glycoform and Infectivity.

Fujihira H, Usami K, Matsuno K, Takeuchi H, Denda-Nagai K, Furukawa JI, Shinohara Y, Takada A, Kawaoka Y, Irimura T.

Sci Rep. 2018 Apr 3;8(1):5495. doi: 10.1038/s41598-018-23357-8.

11.

The effect of an L/N-type calcium channel blocker on intradialytic blood pressure in intradialytic hypertensive patients.

Ito T, Fujimoto N, Ishikawa E, Dohi K, Fujimoto M, Murata T, Kiyohara M, Takeuchi H, Koyabu S, Nishimura H, Takeuchi T, Ito M.

Clin Exp Hypertens. 2019;41(1):92-99. doi: 10.1080/10641963.2018.1445753. Epub 2018 Mar 27.

PMID:
29584458
12.

Cerebrospinal fluid level of Nogo receptor 1 antagonist lateral olfactory tract usher substance (LOTUS) correlates inversely with the extent of neuroinflammation.

Takahashi K, Takeuchi H, Kurihara Y, Doi H, Kunii M, Tanaka K, Nakamura H, Fukai R, Tomita-Katsumoto A, Tada M, Higashiyama Y, Joki H, Koyano S, Takei K, Tanaka F.

J Neuroinflammation. 2018 Feb 17;15(1):46. doi: 10.1186/s12974-018-1084-x.

13.

Variant in human POFUT1 reduces enzymatic activity and likely causes a recessive microcephaly, global developmental delay with cardiac and vascular features.

Takeuchi H, Wong D, Schneider M, Freeze HH, Takeuchi M, Berardinelli SJ, Ito A, Lee H, Nelson SF, Haltiwanger RS.

Glycobiology. 2018 May 1;28(5):276-283. doi: 10.1093/glycob/cwy014.

14.

White matter hyperintensities on MRI in dementia with Lewy bodies, Parkinson's disease with dementia, and Alzheimer's disease.

Joki H, Higashiyama Y, Nakae Y, Kugimoto C, Doi H, Kimura K, Kishida H, Ueda N, Nakano T, Takahashi T, Koyano S, Takeuchi H, Tanaka F.

J Neurol Sci. 2018 Feb 15;385:99-104. doi: 10.1016/j.jns.2017.12.018. Epub 2017 Dec 19.

PMID:
29406924
15.

Cerebellar ataxia-dominant phenotype in patients with ERCC4 mutations.

Doi H, Koyano S, Miyatake S, Nakajima S, Nakazawa Y, Kunii M, Tomita-Katsumoto A, Oda K, Yamaguchi Y, Fukai R, Ikeda S, Kato R, Ogata K, Kubota S, Hayashi N, Takahashi K, Tada M, Tanaka K, Nakashima M, Tsurusaki Y, Miyake N, Saitsu H, Ogi T, Aihara M, Takeuchi H, Matsumoto N, Tanaka F.

J Hum Genet. 2018 Apr;63(4):417-423. doi: 10.1038/s10038-017-0408-5. Epub 2018 Feb 5.

PMID:
29403087
16.

Inhibition of Delta-induced Notch signaling using fucose analogs.

Schneider M, Kumar V, Nordstrøm LU, Feng L, Takeuchi H, Hao H, Luca VC, Garcia KC, Stanley P, Wu P, Haltiwanger RS.

Nat Chem Biol. 2018 Jan;14(1):65-71. doi: 10.1038/nchembio.2520. Epub 2017 Nov 27.

17.

Matrin 3 Is a Component of Neuronal Cytoplasmic Inclusions of Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis.

Tada M, Doi H, Koyano S, Kubota S, Fukai R, Hashiguchi S, Hayashi N, Kawamoto Y, Kunii M, Tanaka K, Takahashi K, Ogawa Y, Iwata R, Yamanaka S, Takeuchi H, Tanaka F.

Am J Pathol. 2018 Feb;188(2):507-514. doi: 10.1016/j.ajpath.2017.10.007. Epub 2017 Nov 9.

PMID:
29128563
18.

Echocardiographic Assessment of Cardiac Structural and Functional Abnormalities in Patients With End-Stage Renal Disease Receiving Chronic Hemodialysis.

Matsuo H, Dohi K, Machida H, Takeuchi H, Aoki T, Nishimura H, Yasutomi M, Senga M, Ichikawa T, Kakuta K, Mizutani Y, Tanoue A, Isaka N, Oosugi K, Koyabu S, Sakurai M, Fukui Y, Kakimoto H, Sugimoto T, Ohnishi T, Murata T, Ishikawa E, Okamoto R, Yamada T, Ogura T, Nishimura Y, Tanigawa T, Nomura S, Nishikawa M, Ito M.

Circ J. 2018 Jan 25;82(2):586-595. doi: 10.1253/circj.CJ-17-0393. Epub 2017 Oct 31.

19.

Functional characterization of zebrafish orthologs of the human Beta 3-Glucosyltransferase B3GLCT gene mutated in Peters Plus Syndrome.

Weh E, Takeuchi H, Muheisen S, Haltiwanger RS, Semina EV.

PLoS One. 2017 Sep 19;12(9):e0184903. doi: 10.1371/journal.pone.0184903. eCollection 2017.

20.

O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking.

Takeuchi H, Yu H, Hao H, Takeuchi M, Ito A, Li H, Haltiwanger RS.

J Biol Chem. 2017 Sep 22;292(38):15964-15973. doi: 10.1074/jbc.M117.800102. Epub 2017 Jul 20.

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