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Items: 1 to 20 of 117

1.

Two novel protein O-glucosyltransferases that modify sites distinct from POGLUT1 and affect Notch trafficking and signaling.

Takeuchi H, Schneider M, Williamson DB, Ito A, Takeuchi M, Handford PA, Haltiwanger RS.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8395-E8402. doi: 10.1073/pnas.1804005115. Epub 2018 Aug 20.

PMID:
30127001
2.

Structural Divergence in O-GlcNAc Glycans Displayed on Epidermal Growth Factor-like Repeats of Mammalian Notch1.

Ogawa M, Senoo Y, Ikeda K, Takeuchi H, Okajima T.

Molecules. 2018 Jul 17;23(7). pii: E1745. doi: 10.3390/molecules23071745.

3.

Metformin treatment ameliorates diabetes-associated decline in hippocampal neurogenesis and memory via phosphorylation of insulin receptor substrate 1.

Tanokashira D, Kurata E, Fukuokaya W, Kawabe K, Kashiwada M, Takeuchi H, Nakazato M, Taguchi A.

FEBS Open Bio. 2018 May 18;8(7):1104-1118. doi: 10.1002/2211-5463.12436. eCollection 2018 Jul.

4.

A central-acting connexin inhibitor, INI-0602, prevents high-fat diet-induced feeding pattern disturbances and obesity in mice.

Sasaki T, Numano R, Yokota-Hashimoto H, Matsui S, Kimura N, Takeuchi H, Kitamura T.

Mol Brain. 2018 May 24;11(1):28. doi: 10.1186/s13041-018-0372-9.

5.

Two cases of anaphylactic shock by methylprednisolone in neuromyelitis optica.

Takahashi K, Asano T, Higashiyama Y, Koyano S, Doi H, Takeuchi H, Tanaka F.

Mult Scler. 2018 Apr 1:1352458518763099. doi: 10.1177/1352458518763099. [Epub ahead of print]

PMID:
29671689
6.

A Critical Domain of Ebolavirus Envelope Glycoprotein Determines Glycoform and Infectivity.

Fujihira H, Usami K, Matsuno K, Takeuchi H, Denda-Nagai K, Furukawa JI, Shinohara Y, Takada A, Kawaoka Y, Irimura T.

Sci Rep. 2018 Apr 3;8(1):5495. doi: 10.1038/s41598-018-23357-8.

7.

The effect of an L/N-type calcium channel blocker on intradialytic blood pressure in intradialytic hypertensive patients.

Ito T, Fujimoto N, Ishikawa E, Dohi K, Fujimoto M, Murata T, Kiyohara M, Takeuchi H, Koyabu S, Nishimura H, Takeuchi T, Ito M.

Clin Exp Hypertens. 2018 Mar 27:1-8. doi: 10.1080/10641963.2018.1445753. [Epub ahead of print]

PMID:
29584458
8.

Cerebrospinal fluid level of Nogo receptor 1 antagonist lateral olfactory tract usher substance (LOTUS) correlates inversely with the extent of neuroinflammation.

Takahashi K, Takeuchi H, Kurihara Y, Doi H, Kunii M, Tanaka K, Nakamura H, Fukai R, Tomita-Katsumoto A, Tada M, Higashiyama Y, Joki H, Koyano S, Takei K, Tanaka F.

J Neuroinflammation. 2018 Feb 17;15(1):46. doi: 10.1186/s12974-018-1084-x.

9.

Variant in human POFUT1 reduces enzymatic activity and likely causes a recessive microcephaly, global developmental delay with cardiac and vascular features.

Takeuchi H, Wong D, Schneider M, Freeze HH, Takeuchi M, Berardinelli SJ, Ito A, Lee H, Nelson SF, Haltiwanger RS.

Glycobiology. 2018 May 1;28(5):276-283. doi: 10.1093/glycob/cwy014.

PMID:
29452367
10.

White matter hyperintensities on MRI in dementia with Lewy bodies, Parkinson's disease with dementia, and Alzheimer's disease.

Joki H, Higashiyama Y, Nakae Y, Kugimoto C, Doi H, Kimura K, Kishida H, Ueda N, Nakano T, Takahashi T, Koyano S, Takeuchi H, Tanaka F.

J Neurol Sci. 2018 Feb 15;385:99-104. doi: 10.1016/j.jns.2017.12.018. Epub 2017 Dec 19.

PMID:
29406924
11.

Cerebellar ataxia-dominant phenotype in patients with ERCC4 mutations.

Doi H, Koyano S, Miyatake S, Nakajima S, Nakazawa Y, Kunii M, Tomita-Katsumoto A, Oda K, Yamaguchi Y, Fukai R, Ikeda S, Kato R, Ogata K, Kubota S, Hayashi N, Takahashi K, Tada M, Tanaka K, Nakashima M, Tsurusaki Y, Miyake N, Saitsu H, Ogi T, Aihara M, Takeuchi H, Matsumoto N, Tanaka F.

J Hum Genet. 2018 Apr;63(4):417-423. doi: 10.1038/s10038-017-0408-5. Epub 2018 Feb 5.

PMID:
29403087
12.

Inhibition of Delta-induced Notch signaling using fucose analogs.

Schneider M, Kumar V, Nordstrøm LU, Feng L, Takeuchi H, Hao H, Luca VC, Garcia KC, Stanley P, Wu P, Haltiwanger RS.

Nat Chem Biol. 2018 Jan;14(1):65-71. doi: 10.1038/nchembio.2520. Epub 2017 Nov 27.

13.

Matrin 3 Is a Component of Neuronal Cytoplasmic Inclusions of Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis.

Tada M, Doi H, Koyano S, Kubota S, Fukai R, Hashiguchi S, Hayashi N, Kawamoto Y, Kunii M, Tanaka K, Takahashi K, Ogawa Y, Iwata R, Yamanaka S, Takeuchi H, Tanaka F.

Am J Pathol. 2018 Feb;188(2):507-514. doi: 10.1016/j.ajpath.2017.10.007. Epub 2017 Nov 9.

PMID:
29128563
14.

Echocardiographic Assessment of Cardiac Structural and Functional Abnormalities in Patients With End-Stage Renal Disease Receiving Chronic Hemodialysis.

Matsuo H, Dohi K, Machida H, Takeuchi H, Aoki T, Nishimura H, Yasutomi M, Senga M, Ichikawa T, Kakuta K, Mizutani Y, Tanoue A, Isaka N, Oosugi K, Koyabu S, Sakurai M, Fukui Y, Kakimoto H, Sugimoto T, Ohnishi T, Murata T, Ishikawa E, Okamoto R, Yamada T, Ogura T, Nishimura Y, Tanigawa T, Nomura S, Nishikawa M, Ito M.

Circ J. 2018 Jan 25;82(2):586-595. doi: 10.1253/circj.CJ-17-0393. Epub 2017 Oct 31.

15.

Functional characterization of zebrafish orthologs of the human Beta 3-Glucosyltransferase B3GLCT gene mutated in Peters Plus Syndrome.

Weh E, Takeuchi H, Muheisen S, Haltiwanger RS, Semina EV.

PLoS One. 2017 Sep 19;12(9):e0184903. doi: 10.1371/journal.pone.0184903. eCollection 2017.

16.

O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking.

Takeuchi H, Yu H, Hao H, Takeuchi M, Ito A, Li H, Haltiwanger RS.

J Biol Chem. 2017 Sep 22;292(38):15964-15973. doi: 10.1074/jbc.M117.800102. Epub 2017 Jul 20.

17.

Differential activation of neuronal and glial STAT3 in the spinal cord of the SOD1G93A mouse model of amyotrophic lateral sclerosis.

Ohgomori T, Yamasaki R, Takeuchi H, Kadomatsu K, Kira JI, Jinno S.

Eur J Neurosci. 2017 Aug;46(4):2001-2014. doi: 10.1111/ejn.13650. Epub 2017 Aug 8.

PMID:
28715117
18.

Differential involvement of vesicular and glial glutamate transporters around spinal α-motoneurons in the pathogenesis of SOD1G93A mouse model of amyotrophic lateral sclerosis.

Ohgomori T, Yamasaki R, Takeuchi H, Kadomatsu K, Kira JI, Jinno S.

Neuroscience. 2017 Jul 25;356:114-124. doi: 10.1016/j.neuroscience.2017.05.014. Epub 2017 May 17.

PMID:
28526579
19.

Rapid screening of sugar-nucleotide donor specificities of putative glycosyltransferases.

Sheikh MO, Halmo SM, Patel S, Middleton D, Takeuchi H, Schafer CM, West CM, Haltiwanger RS, Avci FY, Moremen KW, Wells L.

Glycobiology. 2017 Mar 1;27(3):206-212. doi: 10.1093/glycob/cww114.

20.

Unusual life cycle and impact on microfibril assembly of ADAMTS17, a secreted metalloprotease mutated in genetic eye disease.

Hubmacher D, Schneider M, Berardinelli SJ, Takeuchi H, Willard B, Reinhardt DP, Haltiwanger RS, Apte SS.

Sci Rep. 2017 Feb 8;7:41871. doi: 10.1038/srep41871.

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