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Items: 1 to 20 of 155

1.

Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10.

Yokoyama T, Yukuhiro M, Iwasaki Y, Tanaka C, Sankoda K, Fujiwara R, Shibuta A, Higashi T, Motoyama K, Arima H, Yoshida K, Sugimoto N, Morimoto H, Kosako H, Ohshima T, Fujita M.

Sci Rep. 2019 Nov 14;9(1):16825. doi: 10.1038/s41598-019-53259-2.

2.

Hepatocyte-Targeted Delivery of siRNA Polyplex with PEG-Modified Lactosylated Dendrimer/Cyclodextrin Conjugates for Transthyretin-Related Amyloidosis Therapy.

Hayashi Y, Higashi T, Motoyama K, Jono H, Ando Y, Onodera R, Arima H.

Biol Pharm Bull. 2019;42(10):1679-1688. doi: 10.1248/bpb.b19-00278.

3.

Sacran Hydrogel Film Containing Keratinocyte Growth Factor Accelerates Wound Healing by Stimulating Fibroblast Migration and Re-epithelization.

Wathoni N, Rusdiana T, Hasanah AN, Muhtadi A, Pratiwi ED, Mahmudah R, Mohammed AFA, Okajima M, Kaneko T, Arima H.

Chem Pharm Bull (Tokyo). 2019;67(8):849-854. doi: 10.1248/cpb.c19-00291.

4.

A comprehensive understanding of lowly-hydrolyzed polyvinyl alcohol-based ternary solid dispersions with the use of a combined mixture-process design.

Mori Y, Higashi T, Motoyama K, Ishida M, Onodera R, Arima H.

Drug Dev Ind Pharm. 2019 Oct;45(10):1599-1609. doi: 10.1080/03639045.2019.1640720. Epub 2019 Aug 13.

PMID:
31271320
5.

In vivo Efficacy and Safety Evaluation of Lactosyl-β-cyclodextrin as a Therapeutic Agent for Hepatomegaly in Niemann-Pick Type C Disease.

Maeda Y, Motoyama K, Nishiyama R, Higashi T, Onodera R, Nakamura H, Takeo T, Nakagata N, Yamada Y, Ishitsuka Y, Kondo Y, Irie T, Era T, Arima H.

Nanomaterials (Basel). 2019 May 25;9(5). pii: E802. doi: 10.3390/nano9050802.

6.

The Use of Enteric Capsules for Releasing a Fragrance over an Extended Period of Time.

Ishiguro T, Sakata Y, Arima H, Iohara D, Anraku M, Uekama K, Hirayama F.

Chem Pharm Bull (Tokyo). 2019;67(5):493-497. doi: 10.1248/cpb.c18-00898.

7.

In Vitro and In Vivo Co-delivery of siRNA and Doxorubicin by Folate-PEG-Appended Dendrimer/Glucuronylglucosyl-β-Cyclodextrin Conjugate.

Mohammed AFA, Higashi T, Motoyama K, Ohyama A, Onodera R, Khaled KA, Sarhan HA, Hussein AK, Arima H.

AAPS J. 2019 Apr 16;21(4):54. doi: 10.1208/s12248-019-0327-9.

PMID:
30993472
8.

Therapeutic Potential of Polyamidoamine Dendrimer for Amyloidogenic Transthyretin Amyloidosis.

Inoue M, Ueda M, Higashi T, Anno T, Fujisawa K, Motoyama K, Mizuguchi M, Ando Y, Jono H, Arima H.

ACS Chem Neurosci. 2019 May 15;10(5):2584-2590. doi: 10.1021/acschemneuro.9b00059. Epub 2019 Mar 26.

PMID:
30912637
9.

[Potential Use of Sacran for Dermal and Oral Preparations].

Arima H, Motoyama K, Higashi T.

Yakugaku Zasshi. 2019;139(3):385-391. doi: 10.1248/yakushi.18-00177-5. Review. Japanese.

10.

[Fascination of Cyanobacterium Aphanothece sacrum and Sacran as Functional Materials].

Arima H, Kaneko T.

Yakugaku Zasshi. 2019;139(3):349-350. doi: 10.1248/yakushi.18-00177-F. Japanese. No abstract available.

11.

[Supramolecular Pharmaceutical Sciences: A Novel Concept for Future Pharmaceutical Sciences].

Higashi T, Motoyama K, Arima H.

Yakugaku Zasshi. 2019;139(2):175-183. doi: 10.1248/yakushi.18-00168-4. Review. Japanese.

12.

DAMP-Inducing Adjuvant and PAMP Adjuvants Parallelly Enhance Protective Type-2 and Type-1 Immune Responses to Influenza Split Vaccination.

Hayashi T, Momota M, Kuroda E, Kusakabe T, Kobari S, Makisaka K, Ohno Y, Suzuki Y, Nakagawa F, Lee MSJ, Coban C, Onodera R, Higashi T, Motoyama K, Ishii KJ, Arima H.

Front Immunol. 2018 Nov 20;9:2619. doi: 10.3389/fimmu.2018.02619. eCollection 2018.

13.

Preparation and evaluation of freeze dried surface-deacetylated chitin nanofiber/sacran pellets for use as an extended-release excipient.

Goto M, Ifuku S, Azuma K, Arima H, Kaneko S, Iohara D, Hirayama F, Anraku M.

Int J Biol Macromol. 2019 Mar 1;124:888-894. doi: 10.1016/j.ijbiomac.2018.11.225. Epub 2018 Nov 26.

PMID:
30496863
14.

Theoretical and practical evaluation of lowly hydrolyzed polyvinyl alcohol as a potential carrier for hot-melt extrusion.

Mori Y, Motoyama K, Ishida M, Onodera R, Higashi T, Arima H.

Int J Pharm. 2019 Jan 30;555:124-134. doi: 10.1016/j.ijpharm.2018.11.037. Epub 2018 Nov 15.

PMID:
30448311
15.

Identification of molecular-interaction sites between lowly hydrolyzed polyvinyl alcohols and indomethacin by NMR spectroscopy.

Mori Y, Takahashi M, Ohno Y, Okura R, Ishida M, Higashi T, Motoyama K, Arima H.

Int J Pharm. 2018 Oct 5;549(1-2):456-465. doi: 10.1016/j.ijpharm.2018.08.018. Epub 2018 Aug 12.

PMID:
30110620
16.

[Potential Use of Sacran Hydrogels as Wound Dressing Material].

Motoyama K, Higashi T, Okajima MK, Kaneko T, Arima H.

Yakugaku Zasshi. 2018;138(4):517-520. doi: 10.1248/yakushi.17-00201-5. Review. Japanese.

17.

[Anti-inflammatory Effect of Sacran on Atopic Dermatitis].

Arima H, Motoyama K, Higashi T, Fukushima S, Ihn H.

Yakugaku Zasshi. 2018;138(4):509-515. doi: 10.1248/yakushi.17-00201-4. Review. Japanese.

18.

[Fascination of Sacran, a Polysaccharide from Aphanothece sacrum].

Arima H, Kaneko T.

Yakugaku Zasshi. 2018;138(4):487-488. doi: 10.1248/yakushi.17-00201-F. Japanese. No abstract available.

19.

Predicting the Binding Mode of 2-Hydroxypropyl-β-cyclodextrin to Cholesterol by Means of the MD Simulation and the 3D-RISM-KH Theory.

Hayashino Y, Sugita M, Arima H, Irie T, Kikuchi T, Hirata F.

J Phys Chem B. 2018 May 31;122(21):5716-5725. doi: 10.1021/acs.jpcb.8b02098. Epub 2018 Mar 19.

PMID:
29534570
20.

Supramolecular Pharmaceutical Sciences: A Novel Concept Combining Pharmaceutical Sciences and Supramolecular Chemistry with a Focus on Cyclodextrin-Based Supermolecules.

Higashi T, Iohara D, Motoyama K, Arima H.

Chem Pharm Bull (Tokyo). 2018;66(3):207-216. doi: 10.1248/cpb.c17-00765. Review.

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