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Items: 1 to 20 of 40


A Critical Review of Animal Models Used in Acute Myeloid Leukemia Pathophysiology.

Skayneh H, Jishi B, Hleihel R, Hamieh M, Darwiche N, Bazarbachi A, El Sabban M, El Hajj H.

Genes (Basel). 2019 Aug 13;10(8). pii: E614. doi: 10.3390/genes10080614. Review.


EAPB0503: An Imiquimod analog with potent in vitro activity against cutaneous leishmaniasis caused by Leishmania major and Leishmania tropica.

El Hajj R, Bou Youness H, Lachaud L, Bastien P, Masquefa C, Bonnet PA, El Hajj H, Khalifeh I.

PLoS Negl Trop Dis. 2018 Nov 21;12(11):e0006854. doi: 10.1371/journal.pntd.0006854. eCollection 2018 Nov.


Acute disseminated encephalomyelitis and reactivation of cerebral toxoplasmosis in a child: Case report.

Bannoura S, El Hajj R, Khalifeh I, El Hajj H.

IDCases. 2018 Aug 6;13:e00434. doi: 10.1016/j.idcr.2018.e00434. eCollection 2018.


Conditional knock-down of a novel coccidian protein leads to the formation of aberrant apical organelles and abrogates mature rhoptry positioning in Toxoplasma gondii.

Morlon-Guyot J, Berry L, Sauquet I, Singh Pall G, El Hajj H, Meissner M, Daher W.

Mol Biochem Parasitol. 2018 Jul;223:19-30. doi: 10.1016/j.molbiopara.2018.06.003. Epub 2018 Jun 27.


A proteomic analysis unravels novel CORVET and HOPS proteins involved in Toxoplasma gondii secretory organelles biogenesis.

Morlon-Guyot J, El Hajj H, Martin K, Fois A, Carrillo A, Berry L, Burchmore R, Meissner M, Lebrun M, Daher W.

Cell Microbiol. 2018 Nov;20(11):e12870. doi: 10.1111/cmi.12870. Epub 2018 Jul 8.


Fatal Visceral Leishmaniasis Caused by Leishmania infantum, Lebanon.

El Hajj R, El Hajj H, Khalifeh I.

Emerg Infect Dis. 2018 May;24(5):906-907. doi: 10.3201/eid2405.180019.


Mouse Models That Enhanced Our Understanding of Adult T Cell Leukemia.

Moodad S, Akkouche A, Hleihel R, Darwiche N, El-Sabban M, Bazarbachi A, El Hajj H.

Front Microbiol. 2018 Mar 28;9:558. doi: 10.3389/fmicb.2018.00558. eCollection 2018. Review.


RON4L1 is a new member of the moving junction complex in Toxoplasma gondii.

Guérin A, El Hajj H, Penarete-Vargas D, Besteiro S, Lebrun M.

Sci Rep. 2017 Dec 20;7(1):17907. doi: 10.1038/s41598-017-18010-9.


Characterization of Toxoplasma DegP, a rhoptry serine protease crucial for lethal infection in mice.

Lentini G, El Hajj H, Papoin J, Fall G, Pfaff AW, Tawil N, Braun-Breton C, Lebrun M.

PLoS One. 2017 Dec 15;12(12):e0189556. doi: 10.1371/journal.pone.0189556. eCollection 2017.


Seroprevalence of Anti-Toxoplasma gondii Antibodies Among Lebanese Pregnant Women.

Nahouli H, El Arnaout N, Chalhoub E, Anastadiadis E, El Hajj H.

Vector Borne Zoonotic Dis. 2017 Dec;17(12):785-790. doi: 10.1089/vbz.2016.2092. Epub 2017 Oct 24.


Efficient invasion by Toxoplasma depends on the subversion of host protein networks.

Guérin A, Corrales RM, Parker ML, Lamarque MH, Jacot D, El Hajj H, Soldati-Favre D, Boulanger MJ, Lebrun M.

Nat Microbiol. 2017 Oct;2(10):1358-1366. doi: 10.1038/s41564-017-0018-1. Epub 2017 Aug 28.


No significant HTLV seroprevalence in German people who inject drugs.

Hohn O, Norley S, Kücherer C, Bazarbachi A, El Hajj H, Marcus U, Zimmermann R, Bannert N.

PLoS One. 2017 Aug 22;12(8):e0183496. doi: 10.1371/journal.pone.0183496. eCollection 2017.


Antitumor Effect of the Atypical Retinoid ST1926 in Acute Myeloid Leukemia and Nanoparticle Formulation Prolongs Lifespan and Reduces Tumor Burden of Xenograft Mice.

El-Houjeiri L, Saad W, Hayar B, Aouad P, Tawil N, Abdel-Samad R, Hleihel R, Hamie M, Mancinelli A, Pisano C, El Hajj H, Darwiche N.

Mol Cancer Ther. 2017 Oct;16(10):2047-2057. doi: 10.1158/1535-7163.MCT-16-0785. Epub 2017 Jun 15.


Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia.

Nabbouh AI, Hleihel RS, Saliba JL, Karam MM, Hamie MH, Wu HJM, Berthier CP, Tawil NM, Bonnet PA, Deleuze-Masquefa C, El Hajj HA.

Cancer. 2017 May 1;123(9):1662-1673. doi: 10.1002/cncr.30515. Epub 2017 Jan 5.


Toxoplasma gondii autophagy-related protein ATG9 is crucial for the survival of parasites in their host.

Nguyen HM, El Hajj H, El Hajj R, Tawil N, Berry L, Lebrun M, Bordat Y, Besteiro S.

Cell Microbiol. 2017 Jun;19(6). doi: 10.1111/cmi.12712. Epub 2017 Jan 10.


The conserved apicomplexan Aurora kinase TgArk3 is involved in endodyogeny, duplication rate and parasite virulence.

Berry L, Chen CT, Reininger L, Carvalho TG, El Hajj H, Morlon-Guyot J, Bordat Y, Lebrun M, Gubbels MJ, Doerig C, Daher W.

Cell Microbiol. 2016 Aug;18(8):1106-1120. doi: 10.1111/cmi.12571. Epub 2016 Feb 22.


Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF).

Bekdash A, Darwish M, Timsah Z, Kassab E, Ghanem H, Najjar V, Ghosn M, Nasser S, El-Hajj H, Bazerbachi A, Liu S, Leppla SH, Frankel AE, Abi-Habib RJ.

Transl Oncol. 2015 Oct;8(5):347-57. doi: 10.1016/j.tranon.2015.07.001.


Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells.

El Hajj H, Dassouki Z, Berthier C, Raffoux E, Ades L, Legrand O, Hleihel R, Sahin U, Tawil N, Salameh A, Zibara K, Darwiche N, Mohty M, Dombret H, Fenaux P, de Thé H, Bazarbachi A.

Blood. 2015 May 28;125(22):3447-54. doi: 10.1182/blood-2014-11-612416. Epub 2015 Mar 23.


ATL response to arsenic/interferon therapy is triggered by SUMO/PML/RNF4-dependent Tax degradation.

Dassouki Z, Sahin U, El Hajj H, Jollivet F, Kfoury Y, Lallemand-Breitenbach V, Hermine O, de Thé H, Bazarbachi A.

Blood. 2015 Jan 15;125(3):474-82. doi: 10.1182/blood-2014-04-572750. Epub 2014 Nov 13.


Identification and characterization of Toxoplasma SIP, a conserved apicomplexan cytoskeleton protein involved in maintaining the shape, motility and virulence of the parasite.

Lentini G, Kong-Hap M, El Hajj H, Francia M, Claudet C, Striepen B, Dubremetz JF, Lebrun M.

Cell Microbiol. 2015 Jan;17(1):62-78. doi: 10.1111/cmi.12337. Epub 2014 Aug 30.

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