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Avian pathogenic Escherichia coli infection of a chicken lung epithelial cell line.

Mol N, Peng L, Esnault E, Quéré P, Haagsman HP, Veldhuizen EJA.

Vet Immunol Immunopathol. 2019 Apr;210:55-59. doi: 10.1016/j.vetimm.2019.03.007. Epub 2019 Mar 19.


Cathelicidins PMAP-36, LL-37 and CATH-2 are similar peptides with different modes of action.

Scheenstra MR, van den Belt M, Tjeerdsma-van Bokhoven JLM, Schneider VAF, Ordonez SR, van Dijk A, Veldhuizen EJA, Haagsman HP.

Sci Rep. 2019 Mar 18;9(1):4780. doi: 10.1038/s41598-019-41246-6.


Involvement of Surfactant Protein D in Ebola Virus Infection Enhancement via Glycoprotein Interaction.

Favier AL, Reynard O, Gout E, van Eijk M, Haagsman HP, Crouch E, Volchkov V, Peyrefitte C, Thielens NM.

Viruses. 2018 Dec 26;11(1). pii: E15. doi: 10.3390/v11010015.


Antifungal activities of surfactant protein D in an environment closely mimicking the lung lining.

Ordonez SR, van Eijk M, Escobar Salazar N, de Cock H, Veldhuizen EJA, Haagsman HP.

Mol Immunol. 2019 Jan;105:260-269. doi: 10.1016/j.molimm.2018.12.003. Epub 2018 Dec 15.


Cathelicidins: Immunomodulatory Antimicrobials.

van Harten RM, van Woudenbergh E, van Dijk A, Haagsman HP.

Vaccines (Basel). 2018 Sep 14;6(3). pii: E63. doi: 10.3390/vaccines6030063. Review.


The potential for immunoglobulins and host defense peptides (HDPs) to reduce the use of antibiotics in animal production.

van Dijk A, Hedegaard CJ, Haagsman HP, Heegaard PMH.

Vet Res. 2018 Jul 31;49(1):68. doi: 10.1186/s13567-018-0558-2. Review.


Inhibition and Eradication of Pseudomonas aeruginosa Biofilms by Host Defence Peptides.

Chen H, Wubbolts RW, Haagsman HP, Veldhuizen EJA.

Sci Rep. 2018 Jul 11;8(1):10446. doi: 10.1038/s41598-018-28842-8.


Avian pathogenic Escherichia coli-induced activation of chicken macrophage HD11 cells.

Peng L, Matthijs MGR, Haagsman HP, Veldhuizen EJA.

Dev Comp Immunol. 2018 Oct;87:75-83. doi: 10.1016/j.dci.2018.05.019. Epub 2018 May 23.


Immunomodulation and effects on microbiota after in ovo administration of chicken cathelicidin-2.

Cuperus T, Kraaij MD, Zomer AL, van Dijk A, Haagsman HP.

PLoS One. 2018 Jun 5;13(6):e0198188. doi: 10.1371/journal.pone.0198188. eCollection 2018.


A new and efficient culture method for porcine bone marrow-derived M1- and M2-polarized macrophages.

Gao J, Scheenstra MR, van Dijk A, Veldhuizen EJA, Haagsman HP.

Vet Immunol Immunopathol. 2018 Jun;200:7-15. doi: 10.1016/j.vetimm.2018.04.002. Epub 2018 Apr 14.


Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus.

van Eijk M, Rynkiewicz MJ, Khatri K, Leymarie N, Zaia J, White MR, Hartshorn KL, Cafarella TR, van Die I, Hessing M, Seaton BA, Haagsman HP.

J Biol Chem. 2018 Jul 6;293(27):10646-10662. doi: 10.1074/jbc.RA117.001430. Epub 2018 May 16.


Role of Soluble Innate Effector Molecules in Pulmonary Defense against Fungal Pathogens.

Ordonez SR, Veldhuizen EJA, van Eijk M, Haagsman HP.

Front Microbiol. 2017 Oct 31;8:2098. doi: 10.3389/fmicb.2017.02098. eCollection 2017. Review.


The Antibacterial and Anti-inflammatory Activity of Chicken Cathelicidin-2 combined with Exogenous Surfactant for the Treatment of Cystic Fibrosis-Associated Pathogens.

Banaschewski BJH, Baer B, Arsenault C, Jazey T, Veldhuizen EJA, Delport J, Gooyers T, Lewis JF, Haagsman HP, Veldhuizen RAW, Yamashita C.

Sci Rep. 2017 Nov 14;7(1):15545. doi: 10.1038/s41598-017-15558-4.


Imaging the Antistaphylococcal Activity of CATH-2: Mechanism of Attack and Regulation of Inflammatory Response.

Schneider VAF, Coorens M, Tjeerdsma-van Bokhoven JLM, Posthuma G, van Dijk A, Veldhuizen EJA, Haagsman HP.

mSphere. 2017 Nov 1;2(6). pii: e00370-17. doi: 10.1128/mSphere.00370-17. eCollection 2017 Nov-Dec.


Killing of Pseudomonas aeruginosa by Chicken Cathelicidin-2 Is Immunogenically Silent, Preventing Lung Inflammation In Vivo.

Coorens M, Banaschewski BJH, Baer BJ, Yamashita C, van Dijk A, Haagsman HP, Veldhuizen RAW, Veldhuizen EJA.

Infect Immun. 2017 Nov 17;85(12). pii: e00546-17. doi: 10.1128/IAI.00546-17. Print 2017 Dec.


CATH-2 and LL-37 increase mannose receptor expression, antigen presentation and the endocytic capacity of chicken mononuclear phagocytes.

Kraaij MD, van Dijk A, Haagsman HP.

Mol Immunol. 2017 Oct;90:118-125. doi: 10.1016/j.molimm.2017.07.005. Epub 2017 Jul 14.


Cathelicidins Inhibit Escherichia coli-Induced TLR2 and TLR4 Activation in a Viability-Dependent Manner.

Coorens M, Schneider VAF, de Groot AM, van Dijk A, Meijerink M, Wells JM, Scheenstra MR, Veldhuizen EJA, Haagsman HP.

J Immunol. 2017 Aug 15;199(4):1418-1428. doi: 10.4049/jimmunol.1602164. Epub 2017 Jul 14.


Chicken mannose binding lectin has antiviral activity towards infectious bronchitis virus.

Zhang W, Bouwman KM, van Beurden SJ, Ordonez SR, van Eijk M, Haagsman HP, Verheije MH, Veldhuizen EJA.

Virology. 2017 Sep;509:252-259. doi: 10.1016/j.virol.2017.06.028. Epub 2017 Jul 4.


Antimicrobial and Immunomodulatory Activity of PMAP-23 Derived Peptides.

Veldhuizen EJA, Scheenstra MR, Tjeerdsma-van Bokhoven JLM, Coorens M, Schneider VAF, Bikker FJ, van Dijk A, Haagsman HP.

Protein Pept Lett. 2017;24(7):609-616. doi: 10.2174/0929866524666170428150925.


Characterization of bovine embryos cultured under conditions appropriate for sustaining human naïve pluripotency.

Brinkhof B, van Tol HT, Groot Koerkamp MJ, Wubbolts RW, Haagsman HP, Roelen BA.

PLoS One. 2017 Feb 27;12(2):e0172920. doi: 10.1371/journal.pone.0172920. eCollection 2017.

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