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Items: 1 to 20 of 140

1.

Macrophage galactose-type lectin (MGL) is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation.

Ilarregui JM, Kooij G, Rodríguez E, van der Pol SMA, Koning N, Kalay H, van der Horst JC, van Vliet SJ, García-Vallejo JJ, de Vries HE, van Kooyk Y.

J Neuroinflammation. 2019 Jun 27;16(1):130. doi: 10.1186/s12974-019-1522-4.

2.

Induction of brain-infiltrating T-bet-expressing B cells in multiple sclerosis.

van Langelaar J, Rijvers L, Janssen M, Wierenga-Wolf AF, Melief MJ, Siepman TA, de Vries HE, Unger PA, van Ham SM, Hintzen RQ, van Luijn MM.

Ann Neurol. 2019 Aug;86(2):264-278. doi: 10.1002/ana.25508. Epub 2019 Jun 19.

PMID:
31136008
3.

Reduced Angiopoietin-Like 4 Expression in Multiple Sclerosis Lesions Facilitates Lipid Uptake by Phagocytes via Modulation of Lipoprotein-Lipase Activity.

Kamermans A, Rijnsburger M, Chakraborty A, van der Pol S, de Vries HE, van Horssen J.

Front Immunol. 2019 May 3;10:950. doi: 10.3389/fimmu.2019.00950. eCollection 2019.

4.

Astrocytic ceramide as possible indicator of neuroinflammation.

de Wit NM, den Hoedt S, Martinez-Martinez P, Rozemuller AJ, Mulder MT, de Vries HE.

J Neuroinflammation. 2019 Feb 25;16(1):48. doi: 10.1186/s12974-019-1436-1.

5.

Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology.

Derada Troletti C, Fontijn RD, Gowing E, Charabati M, van Het Hof B, Didouh I, van der Pol SMA, Geerts D, Prat A, van Horssen J, Kooij G, de Vries HE.

Cell Death Dis. 2019 Jan 18;10(2):45. doi: 10.1038/s41419-018-1294-2.

6.

Angiopoietin like-4 as a novel vascular mediator in capillary cerebral amyloid angiopathy.

Chakraborty A, Kamermans A, van Het Hof B, Castricum K, Aanhane E, van Horssen J, Thijssen VL, Scheltens P, Teunissen CE, Fontijn RD, van der Flier WM, de Vries HE.

Brain. 2018 Dec 1;141(12):3377-3388. doi: 10.1093/brain/awy274.

PMID:
30462206
7.

Reactive astrocytes in multiple sclerosis impair neuronal outgrowth through TRPM7-mediated chondroitin sulfate proteoglycan production.

Kamermans A, Planting KE, Jalink K, van Horssen J, de Vries HE.

Glia. 2019 Jan;67(1):68-77. doi: 10.1002/glia.23526. Epub 2018 Nov 19.

8.

Activation of the innate immune system is evident throughout epileptogenesis and is associated with blood-brain barrier dysfunction and seizure progression.

Broekaart DWM, Anink JJ, Baayen JC, Idema S, de Vries HE, Aronica E, Gorter JA, van Vliet EA.

Epilepsia. 2018 Oct;59(10):1931-1944. doi: 10.1111/epi.14550. Epub 2018 Sep 8.

PMID:
30194729
9.

Vascular Endothelial Growth Factor remains unchanged in cerebrospinal fluid of patients with Alzheimer's disease and vascular dementia.

Chakraborty A, Chatterjee M, Twaalfhoven H, Del Campo Milan M, Teunissen CE, Scheltens P, Fontijn RD, van Der Flier WM, de Vries HE.

Alzheimers Res Ther. 2018 Jun 23;10(1):58. doi: 10.1186/s13195-018-0385-8.

10.

Glucocorticoid-mediated modulation of morphological changes associated with aging in microglia.

van Olst L, Bielefeld P, Fitzsimons CP, de Vries HE, Schouten M.

Aging Cell. 2018 Aug;17(4):e12790. doi: 10.1111/acel.12790. Epub 2018 Jun 7.

11.

Mycobacteria employ two different mechanisms to cross the blood-brain barrier.

van Leeuwen LM, Boot M, Kuijl C, Picavet DI, van Stempvoort G, van der Pol SMA, de Vries HE, van der Wel NN, van der Kuip M, van Furth AM, van der Sar AM, Bitter W.

Cell Microbiol. 2018 Sep;20(9):e12858. doi: 10.1111/cmi.12858. Epub 2018 May 30.

12.

T helper 17.1 cells associate with multiple sclerosis disease activity: perspectives for early intervention.

van Langelaar J, van der Vuurst de Vries RM, Janssen M, Wierenga-Wolf AF, Spilt IM, Siepman TA, Dankers W, Verjans GMGM, de Vries HE, Lubberts E, Hintzen RQ, van Luijn MM.

Brain. 2018 May 1;141(5):1334-1349. doi: 10.1093/brain/awy069.

PMID:
29659729
13.

Studying the blood-brain barrier will provide new insights into neurodegeneration - Yes.

Kamphuis WW, De Vries HE.

Mult Scler. 2018 Jul;24(8):1023-1024. doi: 10.1177/1352458518754367. Epub 2018 Mar 5. No abstract available.

14.

Notch signaling is impaired during inflammation in a Lunatic Fringe-dependent manner.

Derada Troletti C, Lopes Pinheiro MA, Charabati M, Gowing E, van Het Hof B, van der Pol SMA, Geerts D, Prat A, Fontijn RD, Unger WW, de Vries HE.

Brain Behav Immun. 2018 Mar;69:48-56. doi: 10.1016/j.bbi.2017.12.016. Epub 2017 Dec 28.

PMID:
29289661
15.

Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis.

Beaino W, Janssen B, Kooij G, van der Pol SMA, van Het Hof B, van Horssen J, Windhorst AD, de Vries HE.

J Neuroinflammation. 2017 Dec 22;14(1):259. doi: 10.1186/s12974-017-1034-z.

16.

Serotonin: A mediator of the gut-brain axis in multiple sclerosis.

Malinova TS, Dijkstra CD, de Vries HE.

Mult Scler. 2018 Aug;24(9):1144-1150. doi: 10.1177/1352458517739975. Epub 2017 Nov 9.

17.

Synthesis, Radiosynthesis, and Preliminary in vitro and in vivo Evaluation of the Fluorinated Ceramide Trafficking Inhibitor (HPA-12) for Brain Applications.

Crivelli SM, Paulus A, Markus J, Bauwens M, Berkes D, De Vries HE, Mulder MT, Walter J, Mottaghy FM, Losen M, Martinez-Martinez P.

J Alzheimers Dis. 2017;60(3):783-794. doi: 10.3233/JAD-161231.

PMID:
28922150
18.

Optical clearing and fluorescence deep-tissue imaging for 3D quantitative analysis of the brain tumor microenvironment.

Lagerweij T, Dusoswa SA, Negrean A, Hendrikx EML, de Vries HE, Kole J, Garcia-Vallejo JJ, Mansvelder HD, Vandertop WP, Noske DP, Tannous BA, Musters RJP, van Kooyk Y, Wesseling P, Zhao XW, Wurdinger T.

Angiogenesis. 2017 Nov;20(4):533-546. doi: 10.1007/s10456-017-9565-6. Epub 2017 Jul 11.

19.

In Vivo Molecular MRI of ICAM-1 Expression on Endothelium and Leukocytes from Subacute to Chronic Stages After Experimental Stroke.

Deddens LH, van Tilborg GAF, van der Marel K, Hunt H, van der Toorn A, Viergever MA, de Vries HE, Dijkhuizen RM.

Transl Stroke Res. 2017 May 16. doi: 10.1007/s12975-017-0536-4. [Epub ahead of print]

20.

Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation.

Aarts SABM, Seijkens TTP, Kusters PJH, van der Pol SMA, Zarzycka B, Heijnen PDAM, Beckers L, den Toom M, Gijbels MJJ, Boon L, Weber C, de Vries HE, Nicolaes GAF, Dijkstra CD, Kooij G, Lutgens E.

J Neuroinflammation. 2017 May 12;14(1):105. doi: 10.1186/s12974-017-0875-9.

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