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Inorganic Polyphosphates As Storage for and Generator of Metabolic Energy in the Extracellular Matrix.

Müller WEG, Schröder HC, Wang X.

Chem Rev. 2019 Dec 26;119(24):12337-12374. doi: 10.1021/acs.chemrev.9b00460. Epub 2019 Nov 18.


Polyphosphate, the physiological metabolic fuel for corneal cells: a potential biomaterial for ocular surface repair.

Wang X, Gericke A, Ackermann M, Wang S, Neufurth M, Schröder HC, Pfeiffer N, Müller WEG.

Biomater Sci. 2019 Dec 1;7(12):5506-5515. doi: 10.1039/c9bm01289c. Epub 2019 Oct 31.


Transformation of Construction Cement to a Self-Healing Hybrid Binder.

Müller WEG, Tolba E, Wang S, Li Q, Neufurth M, Ackermann M, Muñoz-Espí R, Schröder HC, Wang X.

Int J Mol Sci. 2019 Jun 17;20(12). pii: E2948. doi: 10.3390/ijms20122948.


In Situ Polyphosphate Nanoparticle Formation in Hybrid Poly(vinyl alcohol)/Karaya Gum Hydrogels: A Porous Scaffold Inducing Infiltration of Mesenchymal Stem Cells.

Tolba E, Wang X, Ackermann M, Neufurth M, Muñoz-Espí R, Schröder HC, Müller WEG.

Adv Sci (Weinh). 2018 Nov 13;6(2):1801452. doi: 10.1002/advs.201801452. eCollection 2019 Jan 23.


Biomimetic transformation of polyphosphate microparticles during restoration of damaged teeth.

Ackermann M, Tolba E, Neufurth M, Wang S, Schröder HC, Wang X, Müller WEG.

Dent Mater. 2019 Feb;35(2):244-256. doi: 10.1016/ Epub 2018 Dec 3.


Role of ATP during the initiation of microvascularization: acceleration of an autocrine sensing mechanism facilitating chemotaxis by inorganic polyphosphate.

Müller WEG, Ackermann M, Tolba E, Neufurth M, Ivetac I, Kokkinopoulou M, Schröder HC, Wang X.

Biochem J. 2018 Oct 31;475(20):3255-3273. doi: 10.1042/BCJ20180535.


Transformation of Amorphous Polyphosphate Nanoparticles into Coacervate Complexes: An Approach for the Encapsulation of Mesenchymal Stem Cells.

Müller WEG, Wang S, Tolba E, Neufurth M, Ackermann M, Muñoz-Espí R, Lieberwirth I, Glasser G, Schröder HC, Wang X.

Small. 2018 Jul;14(27):e1801170. doi: 10.1002/smll.201801170. Epub 2018 May 30.


Silicateins, silicatein interactors and cellular interplay in sponge skeletogenesis: formation of glass fiber-like spicules.

Wang X, Schloßmacher U, Wiens M, Batel R, Schröder HC, Müller WEG.

FEBS J. 2018 Apr;285(7):1373. doi: 10.1111/febs.14432. Epub 2018 Mar 23. No abstract available.


Amorphous, Smart, and Bioinspired Polyphosphate Nano/Microparticles: A Biomaterial for Regeneration and Repair of Osteo-Articular Impairments In-Situ.

Müller WEG, Neufurth M, Wang S, Ackermann M, Muñoz-Espí R, Feng Q, Lu Q, Schröder HC, Wang X.

Int J Mol Sci. 2018 Jan 31;19(2). pii: E427. doi: 10.3390/ijms19020427.


Uptake of polyphosphate microparticles in vitro (SaOS-2 and HUVEC cells) followed by an increase of the intracellular ATP pool size.

Müller WEG, Wang S, Wiens M, Neufurth M, Ackermann M, Relkovic D, Kokkinopoulou M, Feng Q, Schröder HC, Wang X.

PLoS One. 2017 Dec 29;12(12):e0188977. doi: 10.1371/journal.pone.0188977. eCollection 2017.


Restoration of Impaired Metabolic Energy Balance (ATP Pool) and Tube Formation Potential of Endothelial Cells under "high glucose", Diabetic Conditions by the Bioinorganic Polymer Polyphosphate.

Wang X, Ackermann M, Neufurth M, Wang S, Li Q, Feng Q, Schröder HC, Müller WEG.

Polymers (Basel). 2017 Nov 4;9(11). pii: E575. doi: 10.3390/polym9110575.


Rebalancing β-Amyloid-Induced Decrease of ATP Level by Amorphous Nano/Micro Polyphosphate: Suppression of the Neurotoxic Effect of Amyloid β-Protein Fragment 25-35.

Müller WEG, Wang S, Ackermann M, Neufurth M, Steffen R, Mecja E, Muñoz-Espí R, Feng Q, Schröder HC, Wang X.

Int J Mol Sci. 2017 Oct 16;18(10). pii: E2154. doi: 10.3390/ijms18102154.


Collagen-inducing biologization of prosthetic material for hernia repair: Polypropylene meshes coated with polyP/collagen.

Ackermann M, Wang X, Wang S, Neufurth M, Schröder HC, Isemer FE, Müller WEG.

J Biomed Mater Res B Appl Biomater. 2018 Aug;106(6):2109-2121. doi: 10.1002/jbm.b.34016. Epub 2017 Oct 10.


3D printing of hybrid biomaterials for bone tissue engineering: Calcium-polyphosphate microparticles encapsulated by polycaprolactone.

Neufurth M, Wang X, Wang S, Steffen R, Ackermann M, Haep ND, Schröder HC, Müller WEG.

Acta Biomater. 2017 Dec;64:377-388. doi: 10.1016/j.actbio.2017.09.031. Epub 2017 Sep 28.


Inorganic polyphosphate induces accelerated tube formation of HUVEC endothelial cells.

Müller WEG, Ackermann M, Wang S, Neufurth M, Muñoz-Espí R, Feng Q, Schröder HC, Wang X.

Cell Mol Life Sci. 2018 Jan;75(1):21-32. doi: 10.1007/s00018-017-2601-2. Epub 2017 Aug 2.


Enhancement of Wound Healing in Normal and Diabetic Mice by Topical Application of Amorphous Polyphosphate. Superior Effect of a Host⁻Guest Composite Material Composed of Collagen (Host) and Polyphosphate (Guest).

Müller WEG, Relkovic D, Ackermann M, Wang S, Neufurth M, Paravic Radicevic A, Ushijima H, Schröder HC, Wang X.

Polymers (Basel). 2017 Jul 22;9(7). pii: E300. doi: 10.3390/polym9070300.


Polyphosphate as a donor of high-energy phosphate for the synthesis of ADP and ATP.

Müller WEG, Wang S, Neufurth M, Kokkinopoulou M, Feng Q, Schröder HC, Wang X.

J Cell Sci. 2017 Aug 15;130(16):2747-2756. doi: 10.1242/jcs.204941. Epub 2017 Jul 7.


The Understanding of the Metazoan Skeletal System, Based on the Initial Discoveries with Siliceous and Calcareous Sponges.

Müller WEG, Schröder HC, Wang X.

Mar Drugs. 2017 Jun 12;15(6). pii: E172. doi: 10.3390/md15060172. Review.


Morphogenetically-Active Barrier Membrane for Guided Bone Regeneration, Based on Amorphous Polyphosphate.

Wang X, Ackermann M, Neufurth M, Wang S, Schröder HC, Müller WEG.

Mar Drugs. 2017 May 17;15(5). pii: E142. doi: 10.3390/md15050142.


Bifunctional dentifrice: Amorphous polyphosphate a regeneratively active sealant with potent anti-Streptococcus mutans activity.

Müller WEG, Neufurth M, Ackermann M, Tolba E, Korzhev M, Wang S, Feng Q, Schröder HC, Wang X.

Dent Mater. 2017 Jul;33(7):753-764. doi: 10.1016/ Epub 2017 May 9.


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