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Items: 1 to 20 of 54


Sequestration of Late Antigens Within Viral Factories Impairs MVA Vector-Induced Protective Memory CTL Responses.

Tao S, Tao R, Busch DH, Widera M, Schaal H, Drexler I.

Front Immunol. 2019 Dec 4;10:2850. doi: 10.3389/fimmu.2019.02850. eCollection 2019.


High Concentration of Low-Density Lipoprotein Results in Disturbances in Mitochondrial Transcription and Functionality in Endothelial Cells.

Gonnissen S, Ptok J, Goy C, Jander K, Jakobs P, Eckermann O, Kaisers W, von Ameln F, Timm J, Ale-Agha N, Haendeler J, Schaal H, Altschmied J.

Oxid Med Cell Longev. 2019 Jun 10;2019:7976382. doi: 10.1155/2019/7976382. eCollection 2019.


Context matters: Regulation of splice donor usage.

Ptok J, Müller L, Theiss S, Schaal H.

Biochim Biophys Acta Gene Regul Mech. 2019 Nov - Dec;1862(11-12):194391. doi: 10.1016/j.bbagrm.2019.06.002. Epub 2019 Jun 13. Review.


Gymnotic Delivery of LNA Mixmers Targeting Viral SREs Induces HIV-1 mRNA Degradation.

Hillebrand F, Ostermann PN, Müller L, Degrandi D, Erkelenz S, Widera M, Pfeffer K, Schaal H.

Int J Mol Sci. 2019 Mar 3;20(5). pii: E1088. doi: 10.3390/ijms20051088.


Hierarchical Clustering of DNA k-mer Counts in RNAseq Fastq Files Identifies Sample Heterogeneities.

Kaisers W, Schwender H, Schaal H.

Int J Mol Sci. 2018 Nov 21;19(11). pii: E3687. doi: 10.3390/ijms19113687.


An IL7RA exon 5 polymorphism is associated with impaired IL-7Rα splicing and protection against tuberculosis in Ghana.

Lundtoft C, Awuah AA, Güler A, Harling K, Schaal H, Mayatepek E, Phillips RO, Nausch N, Owusu-Dabo E, Jacobsen M.

Genes Immun. 2019 Jul;20(6):514-519. doi: 10.1038/s41435-018-0049-5. Epub 2018 Oct 31.


Ranking noncanonical 5' splice site usage by genome-wide RNA-seq analysis and splicing reporter assays.

Erkelenz S, Theiss S, Kaisers W, Ptok J, Walotka L, Müller L, Hillebrand F, Brillen AL, Sladek M, Schaal H.

Genome Res. 2018 Dec;28(12):1826-1840. doi: 10.1101/gr.235861.118. Epub 2018 Oct 24.


Identification of a novel Dlg2 isoform differentially expressed in IFNβ-producing plasmacytoid dendritic cells.

Ali S, Hoven A, Dress RJ, Schaal H, Alferink J, Scheu S.

BMC Genomics. 2018 Mar 12;19(1):194. doi: 10.1186/s12864-018-4573-5.


Behind the scenes of HIV-1 replication: Alternative splicing as the dependency factor on the quiet.

Sertznig H, Hillebrand F, Erkelenz S, Schaal H, Widera M.

Virology. 2018 Mar;516:176-188. doi: 10.1016/j.virol.2018.01.011. Review.


Sample Size Estimation for Detection of Splicing Events in Transcriptome Sequencing Data.

Kaisers W, Schwender H, Schaal H.

Int J Mol Sci. 2017 Sep 5;18(9). pii: E1900. doi: 10.3390/ijms18091900.


Validation of Splicing Events in Transcriptome Sequencing Data.

Kaisers W, Ptok J, Schwender H, Schaal H.

Int J Mol Sci. 2017 May 23;18(6). pii: E1110. doi: 10.3390/ijms18061110.


Age, gender and UV-exposition related effects on gene expression in in vivo aged short term cultivated human dermal fibroblasts.

Kaisers W, Boukamp P, Stark HJ, Schwender H, Tigges J, Krutmann J, Schaal H.

PLoS One. 2017 May 5;12(5):e0175657. doi: 10.1371/journal.pone.0175657. eCollection 2017.


Analysis of Competing HIV-1 Splice Donor Sites Uncovers a Tight Cluster of Splicing Regulatory Elements within Exon 2/2b.

Brillen AL, Walotka L, Hillebrand F, Müller L, Widera M, Theiss S, Schaal H.

J Virol. 2017 Jun 26;91(14). pii: e00389-17. doi: 10.1128/JVI.00389-17. Print 2017 Jul 15.


A purine-rich element in foamy virus pol regulates env splicing and gag/pol expression.

Moschall R, Denk S, Erkelenz S, Schenk C, Schaal H, Bodem J.

Retrovirology. 2017 Feb 6;14(1):10. doi: 10.1186/s12977-017-0337-6.


Succession of splicing regulatory elements determines cryptic 5΄ss functionality.

Brillen AL, Schöneweis K, Walotka L, Hartmann L, Müller L, Ptok J, Kaisers W, Poschmann G, Stühler K, Buratti E, Theiss S, Schaal H.

Nucleic Acids Res. 2017 Apr 20;45(7):4202-4216. doi: 10.1093/nar/gkw1317.


Differential hnRNP D isoform incorporation may confer plasticity to the ESSV-mediated repressive state across HIV-1 exon 3.

Hillebrand F, Peter JO, Brillen AL, Otte M, Schaal H, Erkelenz S.

Biochim Biophys Acta Gene Regul Mech. 2017 Feb;1860(2):205-217. doi: 10.1016/j.bbagrm.2016.12.001. Epub 2016 Dec 3.


Exon-skipping and mRNA decay in human liver tissue: molecular consequences of pathogenic bile salt export pump mutations.

Dröge C, Schaal H, Engelmann G, Wenning D, Häussinger D, Kubitz R.

Sci Rep. 2016 Apr 26;6:24827. doi: 10.1038/srep24827.


Human endogenous retrovirus HERV-K(HML-2) activity in prostate cancer is dominated by a few loci.

Goering W, Schmitt K, Dostert M, Schaal H, Deenen R, Mayer J, Schulz WA.

Prostate. 2015 Dec;75(16):1958-71. doi: 10.1002/pros.23095. Epub 2015 Sep 18.


Balanced splicing at the Tat-specific HIV-1 3'ss A3 is critical for HIV-1 replication.

Erkelenz S, Hillebrand F, Widera M, Theiss S, Fayyaz A, Degrandi D, Pfeffer K, Schaal H.

Retrovirology. 2015 Mar 28;12:29. doi: 10.1186/s12977-015-0154-8.


rbamtools: an R interface to samtools enabling fast accumulative tabulation of splicing events over multiple RNA-seq samples.

Kaisers W, Schaal H, Schwender H.

Bioinformatics. 2015 May 15;31(10):1663-4. doi: 10.1093/bioinformatics/btu846. Epub 2015 Jan 5.


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