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Items: 1 to 20 of 58

1.

A Single Drop in the Eye - Effects on the Whole Body?

Vaajanen A, Vapaatalo H.

Open Ophthalmol J. 2017 Oct 31;11:305-314. doi: 10.2174/1874364101711010305. eCollection 2017.

2.

Many Faces of Renin-angiotensin System - Focus on Eye.

Holappa M, Vapaatalo H, Vaajanen A.

Open Ophthalmol J. 2017 Jun 19;11:122-142. doi: 10.2174/1874364101711010122. eCollection 2017. Review.

3.

Vascular Calcification, Vitamin K and Warfarin Therapy - Possible or Plausible Connection?

Siltari A, Vapaatalo H.

Basic Clin Pharmacol Toxicol. 2018 Jan;122(1):19-24. doi: 10.1111/bcpt.12834. Epub 2017 Jul 17. Review.

4.

Local corticosterone production and angiotensin-I converting enzyme shedding in a mouse model of intestinal inflammation.

Salmenkari H, Issakainen T, Vapaatalo H, Korpela R.

World J Gastroenterol. 2015 Sep 21;21(35):10072-9. doi: 10.3748/wjg.v21.i35.10072.

5.

Effect of fermented milk product containing lactotripeptides and plant sterol esters on haemodynamics in subjects with the metabolic syndrome--a randomised, double-blind, placebo-controlled study.

Hautaniemi EJ, Tikkakoski AJ, Tahvanainen A, Nordhausen K, Kähönen M, Mattsson T, Luhtala S, Turpeinen AM, Niemelä O, Vapaatalo H, Korpela R, Pörsti IH.

Br J Nutr. 2015 Aug 14;114(3):376-86. doi: 10.1017/S0007114515002032. Epub 2015 Jul 14.

PMID:
26168857
6.

[Renin-angiotensin system (RAS) in the bowel].

Savinen A, Vapaatalo H.

Duodecim. 2014;130(20):2086-91. Review. Finnish.

PMID:
25558606
7.

Does the cis/trans configuration of peptide bonds in bioactive tripeptides play a role in ACE-1 enzyme inhibition?

Siltari A, Viitanen R, Kukkurainen S, Vapaatalo H, Valjakka J.

Biologics. 2014 Feb 11;8:59-65. doi: 10.2147/BTT.S54056. eCollection 2014.

8.

Low serum enterolactone concentration is associated with low colonic Lactobacillus-Enterococcus counts in men but is not affected by a synbiotic mixture in a randomised, placebo-controlled, double-blind, cross-over intervention study.

Holma R, Kekkonen RA, Hatakka K, Poussa T, Vapaatalo H, Adlercreutz H, Korpela R.

Br J Nutr. 2014 Jan 28;111(2):301-9. doi: 10.1017/S0007114513002420. Epub 2013 Aug 7.

PMID:
23919920
9.

Antihypertensive effects of bioactive tripeptides-a random effects meta-analysis.

Turpeinen AM, Järvenpää S, Kautiainen H, Korpela R, Vapaatalo H.

Ann Med. 2013 Feb;45(1):51-6. doi: 10.3109/07853890.2012.663926. Epub 2012 Mar 9. Review.

PMID:
23305234
10.

Plant sterols and casein-derived tripeptides attenuate blood pressure increase in spontaneously hypertensive rats.

Ehlers PI, Kivimäki AS, Siltari A, Turpeinen AM, Korpela R, Vapaatalo H.

Nutr Res. 2012 Apr;32(4):292-300. doi: 10.1016/j.nutres.2012.03.004. Epub 2012 May 2.

PMID:
22575043
11.

Flavonoids eupatorin and sinensetin present in Orthosiphon stamineus leaves inhibit inflammatory gene expression and STAT1 activation.

Laavola M, Nieminen R, Yam MF, Sadikun A, Asmawi MZ, Basir R, Welling J, Vapaatalo H, Korhonen R, Moilanen E.

Planta Med. 2012 May;78(8):779-86. doi: 10.1055/s-0031-1298458. Epub 2012 Apr 19.

PMID:
22516932
12.

A spread containing bioactive milk peptides Ile-Pro-Pro and Val-Pro-Pro, and plant sterols has antihypertensive and cholesterol-lowering effects.

Turpeinen AM, Ikonen M, Kivimäki AS, Kautiainen H, Vapaatalo H, Korpela R.

Food Funct. 2012 Jun;3(6):621-7. doi: 10.1039/c2fo10286b.

PMID:
22398753
13.

Downregulation of Bradykinin type 2 receptor expression in cardiac endothelial cells during senescence.

Nurmi L, Heikkilä HM, Vapaatalo H, Kovanen PT, Lindstedt KA.

J Vasc Res. 2012;49(1):13-23. doi: 10.1159/000329615. Epub 2011 Oct 4.

14.

High blood pressure-lowering and vasoprotective effects of milk products in experimental hypertension.

Ehlers PI, Kivimäki AS, Turpeinen AM, Korpela R, Vapaatalo H.

Br J Nutr. 2011 Nov;106(9):1353-63. doi: 10.1017/S0007114511001723. Epub 2011 May 10.

PMID:
21736845
15.

Ile-Pro-Pro and Val-Pro-Pro tripeptide-containing milk product has acute blood pressure lowering effects in mildly hypertensive subjects.

Turpeinen AM, Ehlers PI, Kivimäki AS, Järvenpää S, Filler I, Wiegert E, Jähnchen E, Vapaatalo H, Korpela R, Wagner F.

Clin Exp Hypertens. 2011;33(6):388-96. doi: 10.3109/10641963.2010.549267. Epub 2011 Jun 7.

PMID:
21649532
16.

Local ocular renin-angiotensin system - a target for glaucoma therapy?

Vaajanen A, Vapaatalo H.

Basic Clin Pharmacol Toxicol. 2011 Oct;109(4):217-24. doi: 10.1111/j.1742-7843.2011.00729.x. Epub 2011 Jul 28. Review.

17.

Metabolism of ophthalmic timolol: new aspects of an old drug.

Volotinen M, Hakkola J, Pelkonen O, Vapaatalo H, Mäenpää J.

Basic Clin Pharmacol Toxicol. 2011 May;108(5):297-303. doi: 10.1111/j.1742-7843.2011.00694.x. Review.

18.

Effects of flavonoids on prostaglandin E2 production and on COX-2 and mPGES-1 expressions in activated macrophages.

Hämäläinen M, Nieminen R, Asmawi MZ, Vuorela P, Vapaatalo H, Moilanen E.

Planta Med. 2011 Sep;77(13):1504-11. doi: 10.1055/s-0030-1270762. Epub 2011 Feb 21.

PMID:
21341175
19.

Persistence of probiotic strains in the gastrointestinal tract when administered as capsules, yoghurt, or cheese.

Saxelin M, Lassig A, Karjalainen H, Tynkkynen S, Surakka A, Vapaatalo H, Järvenpää S, Korpela R, Mutanen M, Hatakka K.

Int J Food Microbiol. 2010 Dec 15;144(2):293-300. doi: 10.1016/j.ijfoodmicro.2010.10.009. Epub 2010 Oct 21.

PMID:
21074284
20.

Casein-derived tripeptide Ile-Pro-Pro improves angiotensin-(1-7)- and bradykinin-induced rat mesenteric artery relaxation.

Ehlers PI, Nurmi L, Turpeinen AM, Korpela R, Vapaatalo H.

Life Sci. 2011 Jan 31;88(5-6):206-11. doi: 10.1016/j.lfs.2010.11.001. Epub 2010 Nov 4.

PMID:
21056585

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