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Items: 1 to 20 of 45

1.

Inhibitory and Inductive Effects of Opuntia ficus indica Extract and Its Flavonoid Constituents on Cytochrome P450s and UDP-Glucuronosyltransferases.

Jeong H, Kim S, Kim MY, Lee J, An BH, Kim HD, Jeong H, Song YS, Chang M.

Int J Mol Sci. 2018 Oct 30;19(11). pii: E3400. doi: 10.3390/ijms19113400.

2.

Hepatic Metabolism of Sakuranetin and Its Modulating Effects on Cytochrome P450s and UDP-Glucuronosyltransferases.

Jeong H, Lee J, Kim S, Yeo YY, So H, Wu H, Song YS, Jang CY, Kim HD, Kim MJ, Chang M.

Molecules. 2018 Jun 26;23(7). pii: E1542. doi: 10.3390/molecules23071542.

3.

2-Methylacrylamide as a bioisoster of thiourea group for 1,3-dibenzylthioureido TRPV1 receptor antagonists.

Park SR, Kim J, Lee SY, Park YH, Kim HD.

Bioorg Med Chem Lett. 2018 Jun 15;28(11):2080-2083. doi: 10.1016/j.bmcl.2018.04.044. Epub 2018 Apr 17.

PMID:
29709253
4.

Asymmetric synthesis of H1 receptor antagonist (R,R)-clemastine.

Lee SY, Jung JW, Kim TH, Kim HD.

Arch Pharm Res. 2015 Dec;38(12):2131-6. doi: 10.1007/s12272-015-0641-4. Epub 2015 Jul 29.

PMID:
26219510
5.

Psoralidin, a coumestan analogue, as a novel potent estrogen receptor signaling molecule isolated from Psoralea corylifolia.

Liu X, Nam JW, Song YS, Viswanath AN, Pae AN, Kil YS, Kim HD, Park JH, Seo EK, Chang M.

Bioorg Med Chem Lett. 2014 Mar 1;24(5):1403-6. doi: 10.1016/j.bmcl.2014.01.029. Epub 2014 Jan 20.

PMID:
24507928
6.

Design, synthesis, and biological evaluation of cyclopropyl analogues of stilbene with raloxifene side chain as subtype-selective ligands for estrogen receptor.

Yeo HL, Song YS, Ryu JH, Kim HD.

Arch Pharm Res. 2013 Sep;36(9):1096-103. doi: 10.1007/s12272-013-0134-2. Epub 2013 Apr 24.

PMID:
23613312
7.

Heterocycle-linked phenylbenzyl amides as novel TRPV1 antagonists and their TRPV1 binding modes: constraint-induced enhancement of in vitro and in vivo activities.

Kim NJ, Li FN, Lee JH, Park SG, Kim K, Lim C, Han YT, Yun H, Jung JW, Park HG, Kim HD, Woo BY, Shin SS, Kim SY, Choi JK, Jeong YS, Park Y, Park YH, Kim DD, Choi S, Suh YG.

Chem Asian J. 2013 Feb;8(2):400-9. doi: 10.1002/asia.201200730. Epub 2012 Dec 3.

PMID:
23208797
8.

Chain branching approach in structure modification of TRPV1 receptor antagonist MK056 and its analogs.

Jang M, Ryu CH, Park YH, Kim HD.

Arch Pharm Res. 2012 Feb;35(2):321-6. doi: 10.1007/s12272-012-0212-x. Epub 2012 Feb 28.

PMID:
22370786
9.

Design and synthesis of 3'-fluoropenciclovir analogues as antiviral agents.

Choi MH, Lee CK, Kim HD.

Arch Pharm Res. 2010 Feb;33(2):197-202. doi: 10.1007/s12272-010-0202-9. Epub 2010 Feb 24.

PMID:
20195818
10.

Silicon switch approach in TRPV1 antagonist MK-056 and its analogues.

Chang M, Park SR, Kim J, Jang M, Park JH, Park JE, Park HG, Suh YG, Jeong YS, Park YH, Kim HD.

Bioorg Med Chem. 2010 Jan 1;18(1):111-6. doi: 10.1016/j.bmc.2009.11.014. Epub 2009 Nov 10.

PMID:
19931463
11.

Synthesis and structural optimization of multiple H-bonding region of diarylalkyl (thio)amides as novel TRPV1 antagonists.

Li FN, Kim NJ, Chang DJ, Jang J, Jang H, Jung JW, Min KH, Jeong YS, Kim SY, Park YH, Kim HD, Park HG, Suh YG.

Bioorg Med Chem. 2009 Dec 15;17(24):8149-60. doi: 10.1016/j.bmc.2009.10.043. Epub 2009 Oct 27.

PMID:
19897373
12.

Design, synthesis, and biological evaluation of novel diarylalkyl amides as TRPV1 antagonists.

Li FN, Kim NJ, Paek SM, Kwon DY, Min KH, Jeong YS, Kim SY, Park YH, Kim HD, Park HG, Suh YG.

Bioorg Med Chem. 2009 May 15;17(10):3557-67. doi: 10.1016/j.bmc.2009.04.010. Epub 2009 Apr 11.

PMID:
19398205
13.

Synthesis of phenylisothiourea derivatives as inhibitors of NO production in LPS activated macrophages.

Jin GH, Lee DY, Cheon YJ, Gim HJ, Kim do H, Kim HD, Ryu JH, Jeon R.

Bioorg Med Chem Lett. 2009 Jun 1;19(11):3088-92. doi: 10.1016/j.bmcl.2009.04.001. Epub 2009 Apr 7.

PMID:
19394216
14.

Synthesis and cytotoxic activities of C-benzylated flavonoids.

Choi YJ, Kim HM, Kim HD.

Arch Pharm Res. 2009 Jan;32(1):59-63. doi: 10.1007/s12272-009-1118-0. Epub 2009 Jan 29.

PMID:
19183877
15.

In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii.

Kim JY, Lim HJ, Lee da Y, Kim JS, Kim DH, Lee HJ, Kim HD, Jeon R, Ryu JH.

Bioorg Med Chem Lett. 2009 Feb 1;19(3):937-40. doi: 10.1016/j.bmcl.2008.11.103. Epub 2008 Dec 26.

PMID:
19110419
16.

Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 expression by xanthanolides isolated from Xanthium strumarium.

Yoon JH, Lim HJ, Lee HJ, Kim HD, Jeon R, Ryu JH.

Bioorg Med Chem Lett. 2008 Mar 15;18(6):2179-82. doi: 10.1016/j.bmcl.2007.12.076. Epub 2008 Feb 2.

PMID:
18276135
17.

Structure-activity relationships of 2-chloro-N6-substituted-4'-thioadenosine-5'-N,N-dialkyluronamides as human A3 adenosine receptor antagonists.

Jeong LS, Lee HW, Kim HO, Tosh DK, Pal S, Choi WJ, Gao ZG, Patel AR, Williams W, Jacobson KA, Kim HD.

Bioorg Med Chem Lett. 2008 Mar 1;18(5):1612-6. doi: 10.1016/j.bmcl.2008.01.070. Epub 2008 Jan 19.

PMID:
18255292
18.
19.

In vitro and in vivo study of poly(ethylene glycol) conjugated ketoprofen to extend the duration of action.

Choi HK, Chun MK, Lee SH, Jang MH, Kim HD, Jung CS, Oh SY.

Int J Pharm. 2007 Aug 16;341(1-2):50-7. Epub 2007 Apr 5.

PMID:
17517483
20.

Suppression of inducible nitric oxide synthase expression by yakuchinones and their analogues.

Lee HJ, Kim JS, Yoon JW, Kim HD, Ryu JH.

Chem Pharm Bull (Tokyo). 2006 Mar;54(3):377-9.

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