Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 19

1.

Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.

Mitchell SJ, Bernier M, Aon MA, Cortassa S, Kim EY, Fang EF, Palacios HH, Ali A, Navas-Enamorado I, Di Francesco A, Kaiser TA, Waltz TB, Zhang N, Ellis JL, Elliott PJ, Frederick DW, Bohr VA, Schmidt MS, Brenner C, Sinclair DA, Sauve AA, Baur JA, de Cabo R.

Cell Metab. 2018 Mar 6;27(3):667-676.e4. doi: 10.1016/j.cmet.2018.02.001.

2.

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice.

Mitchell SJ, Madrigal-Matute J, Scheibye-Knudsen M, Fang E, Aon M, González-Reyes JA, Cortassa S, Kaushik S, Gonzalez-Freire M, Patel B, Wahl D, Ali A, Calvo-Rubio M, Burón MI, Guiterrez V, Ward TM, Palacios HH, Cai H, Frederick DW, Hine C, Broeskamp F, Habering L, Dawson J, Beasley TM, Wan J, Ikeno Y, Hubbard G, Becker KG, Zhang Y, Bohr VA, Longo DL, Navas P, Ferrucci L, Sinclair DA, Cohen P, Egan JM, Mitchell JR, Baur JA, Allison DB, Anson RM, Villalba JM, Madeo F, Cuervo AM, Pearson KJ, Ingram DK, Bernier M, de Cabo R.

Cell Metab. 2016 Jun 14;23(6):1093-1112. doi: 10.1016/j.cmet.2016.05.027.

3.

Cytochrome b5 reductase and the control of lipid metabolism and healthspan.

Martin-Montalvo A, Sun Y, Diaz-Ruiz A, Ali A, Gutierrez V, Palacios HH, Curtis J, Siendones E, Ariza J, Abulwerdi GA, Sun X, Wang AX, Pearson KJ, Fishbein KW, Spencer RG, Wang M, Han X, Scheibye-Knudsen M, Baur JA, Shertzer HG, Navas P, Villalba JM, Zou S, Bernier M, de Cabo R.

NPJ Aging Mech Dis. 2016 May 12;2:16006. doi: 10.1038/npjamd.2016.6. eCollection 2016.

4.

SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass.

Mercken EM, Mitchell SJ, Martin-Montalvo A, Minor RK, Almeida M, Gomes AP, Scheibye-Knudsen M, Palacios HH, Licata JJ, Zhang Y, Becker KG, Khraiwesh H, González-Reyes JA, Villalba JM, Baur JA, Elliott P, Westphal C, Vlasuk GP, Ellis JL, Sinclair DA, Bernier M, de Cabo R.

Aging Cell. 2014 Oct;13(5):787-96. doi: 10.1111/acel.12220. Epub 2014 Jun 16.

5.

Immunocytochemical Characterization of Alzheimer's Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid-β Vaccine.

Carrera I, Etcheverria I, Li Y, Fernandez-Novoa L, Lombardi V, Vigo C, Palacios HH, Benberin VV, Cacabelos R, Aliev G.

Cent Asian J Glob Health. 2014 Mar 27;2(Suppl):119. doi: 10.5195/cajgh.2013.119. eCollection 2013.

6.

The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet.

Mitchell SJ, Martin-Montalvo A, Mercken EM, Palacios HH, Ward TM, Abulwerdi G, Minor RK, Vlasuk GP, Ellis JL, Sinclair DA, Dawson J, Allison DB, Zhang Y, Becker KG, Bernier M, de Cabo R.

Cell Rep. 2014 Mar 13;6(5):836-43. doi: 10.1016/j.celrep.2014.01.031. Epub 2014 Feb 27.

7.

Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet.

Jimenez-Gomez Y, Mattison JA, Pearson KJ, Martin-Montalvo A, Palacios HH, Sossong AM, Ward TM, Younts CM, Lewis K, Allard JS, Longo DL, Belman JP, Malagon MM, Navas P, Sanghvi M, Moaddel R, Tilmont EM, Herbert RL, Morrell CH, Egan JM, Baur JA, Ferrucci L, Bogan JS, Bernier M, de Cabo R.

Cell Metab. 2013 Oct 1;18(4):533-45. doi: 10.1016/j.cmet.2013.09.004.

8.

Immunocytochemical characterization of Alzheimer disease hallmarks in APP/PS1 transgenic mice treated with a new anti-amyloid-β vaccine.

Carrera I, Etcheverría I, Li Y, Fernández-Novoa L, Lombardi V, Vigo C, Palacios HH, Benberin VV, Cacabelos R, Aliev G.

Biomed Res Int. 2013;2013:709145. doi: 10.1155/2013/709145. Epub 2013 Sep 9.

9.

Metformin improves healthspan and lifespan in mice.

Martin-Montalvo A, Mercken EM, Mitchell SJ, Palacios HH, Mote PL, Scheibye-Knudsen M, Gomes AP, Ward TM, Minor RK, Blouin MJ, Schwab M, Pollak M, Zhang Y, Yu Y, Becker KG, Bohr VA, Ingram DK, Sinclair DA, Wolf NS, Spindler SR, Bernier M, de Cabo R.

Nat Commun. 2013;4:2192. doi: 10.1038/ncomms3192.

10.

Oxidative stress induced mitochondrial DNA deletion as a hallmark for the drug development in the context of the cerebrovascular diseases.

Aliev G, Li Y, Palacios HH, Obrenovich ME.

Recent Pat Cardiovasc Drug Discov. 2011 Sep;6(3):222-41. Review.

PMID:
21906026
11.

Effects of coenzyme Q and creatine supplementation on brain energy metabolism in rats exposed to chronic cerebral hypoperfusion.

Horecký J, Gvozdjáková A, Kucharská J, Obrenovich ME, Palacios HH, Li Y, Vančová O, Aliev G.

Curr Alzheimer Res. 2011 Dec;8(8):868-75.

PMID:
21592049
12.

Antioxidants in health, disease and aging.

Obrenovich ME, Li Y, Parvathaneni K, Yendluri BB, Palacios HH, Leszek J, Aliev G.

CNS Neurol Disord Drug Targets. 2011 Mar;10(2):192-207. Review.

PMID:
21226664
13.

Implication of oncogenic signaling pathways as a treatment strategy for neurodegenerative disorders - contemporary approaches.

Sieradzki A, Yendluri BB, Palacios HH, Parvathaneni K, Reddy VP, Obrenovich ME, Gąsiorowski K, Leszek J, Aliev G.

CNS Neurol Disord Drug Targets. 2011 Mar;10(2):175-83. Review.

PMID:
21222633
14.

Mitochondrion-specific antioxidants as drug treatments for Alzheimer disease.

Palacios HH, Yendluri BB, Parvathaneni K, Shadlinski VB, Obrenovich ME, Leszek J, Gokhman D, Gąsiorowski K, Bragin V, Aliev G.

CNS Neurol Disord Drug Targets. 2011 Mar;10(2):149-62. Review.

PMID:
21222631
15.

Oxidative Stress Induced Mitochondrial Failure and Vascular Hypoperfusion as a Key Initiator for the Development of Alzheimer Disease.

Aliev G, Palacios HH, Gasimov E, Obrenovich ME, Morales L, Leszek J, Bragin V, Solís Herrera A, Gokhman D.

Pharmaceuticals (Basel). 2010 Jan 19;3(1):158-187. Review.

16.

In vivo and in vitro assessment of brain bioenergetics in aging rats.

Vančová O, Bačiak L, Kašparová S, Kucharská J, Palacios HH, Horecký J, Aliev G.

J Cell Mol Med. 2010 Nov;14(11):2667-74. doi: 10.1111/j.1582-4934.2009.00879.x.

17.

Brain mitochondria as a primary target in the development of treatment strategies for Alzheimer disease.

Aliev G, Palacios HH, Walrafen B, Lipsitt AE, Obrenovich ME, Morales L.

Int J Biochem Cell Biol. 2009 Oct;41(10):1989-2004. doi: 10.1016/j.biocel.2009.03.015. Epub 2009 Apr 5. Review.

PMID:
19703659
18.

Nitric oxide as an initiator of brain lesions during the development of Alzheimer disease.

Aliev G, Palacios HH, Lipsitt AE, Fischbach K, Lamb BT, Obrenovich ME, Morales L, Gasimov E, Bragin V.

Neurotox Res. 2009 Oct;16(3):293-305. doi: 10.1007/s12640-009-9066-5. Epub 2009 May 30.

PMID:
19526276
19.

The GRK2 Overexpression Is a Primary Hallmark of Mitochondrial Lesions during Early Alzheimer Disease.

Obrenovich ME, Palacios HH, Gasimov E, Leszek J, Aliev G.

Cardiovasc Psychiatry Neurol. 2009;2009:327360. doi: 10.1155/2009/327360. Epub 2010 Mar 3.

Supplemental Content

Loading ...
Support Center