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Items: 1 to 20 of 232


Prospective of nanoscale metal organic frameworks [NMOFs] for cancer therapy.

Shait Mohammed MR, Ahmad V, Ahmad A, Tabrez S, Choudhry H, Zamzami MA, Bakhrebah MA, Ahmad A, Wasi S, Mukhtar H, Khan MI.

Semin Cancer Biol. 2019 Dec 19. pii: S1044-579X(19)30414-6. doi: 10.1016/j.semcancer.2019.12.015. [Epub ahead of print] Review.


Polyalthia longifolia Extract Triggers ER Stress in Prostate Cancer Cells Concomitant with Induction of Apoptosis: Insights from In Vitro and In Vivo Studies.

Afolabi SO, Olorundare OE, Babatunde A, Albrecht RM, Koketsu M, Syed DN, Mukhtar H.

Oxid Med Cell Longev. 2019 Nov 13;2019:6726312. doi: 10.1155/2019/6726312. eCollection 2019.


Hepatic stearoyl CoA desaturase 1 deficiency increases glucose uptake in adipose tissue partially through the PGC-1α-FGF21 axis in mice.

Aljohani A, Khan MI, Bonneville A, Guo C, Jeffery J, O'Neill L, Syed DN, Lewis SA, Burhans M, Mukhtar H, Ntambi JM.

J Biol Chem. 2019 Dec 20;294(51):19475-19485. doi: 10.1074/jbc.RA119.009868. Epub 2019 Nov 5.


Hepatic Stearoyl-CoA desaturase-1 deficiency-mediated activation of mTORC1- PGC-1α axis regulates ER stress during high-carbohydrate feeding.

Aljohani A, Khan MI, Syed DN, Abram B, Lewis S, Neill LO, Mukhtar H, Ntambi JM.

Sci Rep. 2019 Oct 31;9(1):15761. doi: 10.1038/s41598-019-52339-7.


Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models.

Chamcheu JC, Esnault S, Adhami VM, Noll AL, Banang-Mbeumi S, Roy T, Singh SS, Huang S, Kousoulas KG, Mukhtar H.

Cells. 2019 Sep 15;8(9). pii: E1089. doi: 10.3390/cells8091089.


Fisetin and 5-fluorouracil: Effective combination for PIK3CA-mutant colorectal cancer.

Khan N, Jajeh F, Eberhardt EL, Miller DD, Albrecht DM, Van Doorn R, Hruby MD, Maresh ME, Clipson L, Mukhtar H, Halberg RB.

Int J Cancer. 2019 Dec 1;145(11):3022-3032. doi: 10.1002/ijc.32367. Epub 2019 May 10.


Tea Polyphenols in Promotion of Human Health.

Khan N, Mukhtar H.

Nutrients. 2018 Dec 25;11(1). pii: E39. doi: 10.3390/nu11010039. Review.


AKT Inhibition Modulates H3K4 Demethylase Levels in PTEN-Null Prostate Cancer.

Khan MI, Hamid A, Rath S, Ateeq B, Khan Q, Siddiqui IA, Adhami VM, Choudhry H, Zamzami MA, Mukhtar H.

Mol Cancer Ther. 2019 Feb;18(2):356-363. doi: 10.1158/1535-7163.MCT-18-0141. Epub 2018 Nov 16.


Proproliferative function of adaptor protein GRB10 in prostate carcinoma.

Khan MI, Al Johani A, Hamid A, Ateeq B, Manzar N, Adhami VM, Lall RK, Rath S, Sechi M, Siddiqui IA, Choudhry H, Zamzami MA, Havighurst TC, Huang W, Ntambi JM, Mukhtar H.

FASEB J. 2019 Mar;33(3):3198-3211. doi: 10.1096/fj.201800265RR. Epub 2018 Oct 31.


Fisetin targets YB-1/RSK axis independent of its effect on ERK signaling: insights from in vitro and in vivo melanoma models.

Sechi M, Lall RK, Afolabi SO, Singh A, Joshi DC, Chiu SY, Mukhtar H, Syed DN.

Sci Rep. 2018 Oct 24;8(1):15726. doi: 10.1038/s41598-018-33879-w.


India-United States Dialogue on Traditional Medicine: Toward Collaborative Research and Generation of an Evidence Base.

White JD, O'Keefe BR, Sharma J, Javed G, Nukala V, Ganguly A, Khan IA, Kumar NB, Mukhtar H, Pauli GF, Walker L, Sivaram S, Rajaraman P, Trimble EL.

J Glob Oncol. 2018 Sep;4:1-10. doi: 10.1200/JGO.17.00099. Epub 2017 Nov 16. Review.


Chitosan-based nanoformulated (-)-epigallocatechin-3-gallate (EGCG) modulates human keratinocyte-induced responses and alleviates imiquimod-induced murine psoriasiform dermatitis.

Chamcheu JC, Siddiqui IA, Adhami VM, Esnault S, Bharali DJ, Babatunde AS, Adame S, Massey RJ, Wood GS, Longley BJ, Mousa SA, Mukhtar H.

Int J Nanomedicine. 2018 Jul 20;13:4189-4206. doi: 10.2147/IJN.S165966. eCollection 2018.


Nummularic acid, a triterpenoid, from the medicinal plant Fraxinus xanthoxyloides, induces energy crisis to suppress growth of prostate cancer cells.

Younis T, Khan MI, Khan MR, Rasul A, Majid M, Adhami VM, Mukhtar H.

Mol Carcinog. 2018 Oct;57(10):1267-1277. doi: 10.1002/mc.22841. Epub 2018 Jun 5.


Targeting epithelial to mesenchymal transition in prostate cancer by a novel compound, plectranthoic acid, isolated from Ficus microcarpa.

Akhtar N, Syed DN, Lall RK, Mirza B, Mukhtar H.

Mol Carcinog. 2018 May;57(5):653-663. doi: 10.1002/mc.22790. Epub 2018 Feb 27.


Targeting epigenome with dietary nutrients in cancer: Current advances and future challenges.

Khan MI, Rath S, Adhami VM, Mukhtar H.

Pharmacol Res. 2018 Mar;129:375-387. doi: 10.1016/j.phrs.2017.12.008. Epub 2017 Dec 9. Review.


Synthetic transcription elongation factors license transcription across repressive chromatin.

Erwin GS, Grieshop MP, Ali A, Qi J, Lawlor M, Kumar D, Ahmad I, McNally A, Teider N, Worringer K, Sivasankaran R, Syed DN, Eguchi A, Ashraf M, Jeffery J, Xu M, Park PMC, Mukhtar H, Srivastava AK, Faruq M, Bradner JE, Ansari AZ.

Science. 2017 Dec 22;358(6370):1617-1622. doi: 10.1126/science.aan6414. Epub 2017 Nov 30.


Ousting RAGE in melanoma: A viable therapeutic target?

Syed DN, Aljohani A, Waseem D, Mukhtar H.

Semin Cancer Biol. 2018 Apr;49:20-28. doi: 10.1016/j.semcancer.2017.10.008. Epub 2017 Oct 24. Review.


Comparative Antileukemic Activity of a Tetranorditerpene Isolated from Polyalthia longifolia Leaves and the Derivative against Human Leukemia HL-60 Cells.

Afolabi S, Olorundare O, Ninomiya M, Babatunde A, Mukhtar H, Koketsu M.

J Oleo Sci. 2017 Oct 1;66(10):1169-1174. doi: 10.5650/jos.ess17042. Epub 2017 Sep 15.


Hypoxia driven glycation: Mechanisms and therapeutic opportunities.

Khan MI, Rath S, Adhami VM, Mukhtar H.

Semin Cancer Biol. 2018 Apr;49:75-82. doi: 10.1016/j.semcancer.2017.05.008. Epub 2017 May 22. Review.


Melittin, a major peptide component of bee venom, and its conjugates in cancer therapy.

Rady I, Siddiqui IA, Rady M, Mukhtar H.

Cancer Lett. 2017 Aug 28;402:16-31. doi: 10.1016/j.canlet.2017.05.010. Epub 2017 May 20. Review.

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