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Derailed Ceramide Metabolism in Atopic Dermatitis (AD): A Causal Starting Point for a Personalized (Basic) Therapy.

Blaess M, Deigner HP.

Int J Mol Sci. 2019 Aug 15;20(16). pii: E3967. doi: 10.3390/ijms20163967. Review.


Data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrument.

Mahmoud M, Laufer S, Deigner HP.

Data Brief. 2019 Apr 23;24:103946. doi: 10.1016/j.dib.2019.103946. eCollection 2019 Jun.


The potential of click reactions for the synthesis of bioactive triterpenes.

Csuk R, Deigner HP.

Bioorg Med Chem Lett. 2019 Apr 15;29(8):949-958. doi: 10.1016/j.bmcl.2019.02.020. Epub 2019 Feb 19. Review.


An aptamer based thermofluorimetric assay for ethanolamine.

Mahmoud M, Laufer S, Deigner HP.

Biochimie. 2019 Mar;158:233-237. doi: 10.1016/j.biochi.2019.01.014. Epub 2019 Jan 25.


A smartphone readout system for gold nanoparticle-based lateral flow assays: application to monitoring of digoxigenin.

Ruppert C, Phogat N, Laufer S, Kohl M, Deigner HP.

Mikrochim Acta. 2019 Jan 19;186(2):119. doi: 10.1007/s00604-018-3195-6.


Small molecule detection with aptamer based lateral flow assays: Applying aptamer-C-reactive protein cross-recognition for ampicillin detection.

Kaiser L, Weisser J, Kohl M, Deigner HP.

Sci Rep. 2018 Apr 4;8(1):5628. doi: 10.1038/s41598-018-23963-6.


NB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation.

Blaess M, Bibak N, Claus RA, Kohl M, Bonaterra GA, Kinscherf R, Laufer S, Deigner HP.

Eur J Med Chem. 2018 Jun 10;153:73-104. doi: 10.1016/j.ejmech.2017.09.021. Epub 2017 Sep 21.


Crystal structures of pure 3-(4-bromo-2-chloro-phen-yl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one and contaminated with 3-(4-bromo-phen-yl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one.

Wahedy K, Abu Thaher B, Schollmeyer D, Almasri I, Morjan R, Qeshta B, Deigner HP.

Acta Crystallogr E Crystallogr Commun. 2017 Aug 15;73(Pt 9):1341-1343. doi: 10.1107/S2056989017011732. eCollection 2017 Sep 1.


Discovery of biomarkers in rare diseases: innovative approaches by predictive and personalized medicine.

Gülbakan B, Özgül RK, Yüzbaşıoğlu A, Kohl M, Deigner HP, Özgüç M.

EPMA J. 2016 Dec 8;7:24. eCollection 2016. Review.


Bimodal imaging and beyond.

Deigner HP.

Atherosclerosis. 2016 Nov;254:307-308. doi: 10.1016/j.atherosclerosis.2016.10.015. Epub 2016 Oct 8. No abstract available.


Acid Sphingomyelinase Promotes Endothelial Stress Response in Systemic Inflammation and Sepsis.

Chung HY, Hupe DC, Otto GP, Sprenger M, Bunck AC, Dorer MJ, Bockmeyer CL, Deigner HP, Gräler MH, Claus RA.

Mol Med. 2016 Sep;22:412-423. doi: 10.2119/molmed.2016.00140. Epub 2016 Jun 15.


Oxidized Phospholipids Inhibit the Formation of Cholesterol-Dependent Plasma Membrane Nanoplatforms.

Brameshuber M, Sevcsik E, Rossboth BK, Manner C, Deigner HP, Peksel B, Péter M, Török Z, Hermetter A, Schütz GJ.

Biophys J. 2016 Jan 5;110(1):205-13. doi: 10.1016/j.bpj.2015.11.018.


HPLC separation and ultrasensitive optical quantification of ceramide species applying 7-(diethylamino)coumarin-3-carbonyl azide derivatisation.

Blaess M, Claus RA, Deigner HP.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Apr 1;986-987:123-8. doi: 10.1016/j.jchromb.2015.02.014. Epub 2015 Feb 17.


Hyperresponsiveness of mice deficient in plasma-secreted sphingomyelinase reveals its pivotal role in early phase of host response.

Jbeily N, Suckert I, Gonnert FA, Acht B, Bockmeyer CL, Grossmann SD, Blaess MF, Lueth A, Deigner HP, Bauer M, Claus RA.

J Lipid Res. 2013 Feb;54(2):410-24. doi: 10.1194/jlr.M031625. Epub 2012 Dec 10.


Annual Conferences of the European, Middle Eastern and African Society for Biopreservation and Biobanking (ESBB): overview of 2011 and preview of 2012.

Chabannon C, Doran P, Hofman P, Seberg O, Cinotti S, Bledsoe M, Deigner HP, Koschorreck J, Dagher G, Cooreman A, De Blasio P, Riegman P, Hewitt R.

Biopreserv Biobank. 2012 Oct;10(5):407-15. doi: 10.1089/bio.2012.1052. No abstract available.


Inflammatory-induced hibernation in the fetus: priming of fetal sheep metabolism correlates with developmental brain injury.

Keller M, Enot DP, Hodson MP, Igwe EI, Deigner HP, Dean J, Bolouri H, Hagberg H, Mallard C.

PLoS One. 2011;6(12):e29503. doi: 10.1371/journal.pone.0029503. Epub 2011 Dec 29.


Lactoferrin inhibits neutrophil apoptosis via blockade of proximal apoptotic signaling events.

Francis N, Wong SH, Hampson P, Wang K, Young SP, Deigner HP, Salmon M, Scheel-Toellner D, Lord JM.

Biochim Biophys Acta. 2011 Oct;1813(10):1822-6. doi: 10.1016/j.bbamcr.2011.07.004. Epub 2011 Jul 19.


Preprocessing of gene expression data by optimally robust estimators.

Kohl M, Deigner HP.

BMC Bioinformatics. 2010 Nov 30;11:583. doi: 10.1186/1471-2105-11-583.


Targeted metabolomics for biomarker discovery.

Griffiths WJ, Koal T, Wang Y, Kohl M, Enot DP, Deigner HP.

Angew Chem Int Ed Engl. 2010 Jul 26;49(32):5426-45. doi: 10.1002/anie.200905579. Review.


Complexity and pitfalls of mass spectrometry-based targeted metabolomics in brain research.

Urban M, Enot DP, Dallmann G, Körner L, Forcher V, Enoh P, Koal T, Keller M, Deigner HP.

Anal Biochem. 2010 Nov 15;406(2):124-31. doi: 10.1016/j.ab.2010.07.002. Epub 2010 Jul 7.


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