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Items: 1 to 20 of 41


The generation and use of recombinant extracellular vesicles as biological reference material.

Geeurickx E, Tulkens J, Dhondt B, Van Deun J, Lippens L, Vergauwen G, Heyrman E, De Sutter D, Gevaert K, Impens F, Miinalainen I, Van Bockstal PJ, De Beer T, Wauben MHM, Nolte-'t-Hoen ENM, Bloch K, Swinnen JV, van der Pol E, Nieuwland R, Braems G, Callewaert N, Mestdagh P, Vandesompele J, Denys H, Eyckerman S, De Wever O, Hendrix A.

Nat Commun. 2019 Jul 23;10(1):3288. doi: 10.1038/s41467-019-11182-0.


The Role of Epithelial-to-Mesenchymal Plasticity in Ovarian Cancer Progression and Therapy Resistance.

Loret N, Denys H, Tummers P, Berx G.

Cancers (Basel). 2019 Jun 17;11(6). pii: E838. doi: 10.3390/cancers11060838. Review.


PRIMMO study protocol: a phase II study combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer.

Tuyaerts S, Van Nuffel AMT, Naert E, Van Dam PA, Vuylsteke P, De Caluwé A, Aspeslagh S, Dirix P, Lippens L, De Jaeghere E, Amant F, Vandecasteele K, Denys H.

BMC Cancer. 2019 May 28;19(1):506. doi: 10.1186/s12885-019-5676-3.


Corneal features in trastuzumab emtansine treatment: not a rare occurrence.

Deklerck E, Denys H, Kreps EO.

Breast Cancer Res Treat. 2019 Jun;175(2):525-530. doi: 10.1007/s10549-019-05179-y. Epub 2019 Feb 28.


Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction.

Tulkens J, Vergauwen G, Van Deun J, Geeurickx E, Dhondt B, Lippens L, De Scheerder MA, Miinalainen I, Rappu P, De Geest BG, Vandecasteele K, Laukens D, Vandekerckhove L, Denys H, Vandesompele J, De Wever O, Hendrix A.

Gut. 2018 Dec 5. pii: gutjnl-2018-317726. doi: 10.1136/gutjnl-2018-317726. [Epub ahead of print] No abstract available.


Neo-adjuvant treatment of adenocarcinoma and squamous cell carcinoma of the cervix results in significantly different pathological complete response rates.

Couvreur K, Naert E, De Jaeghere E, Tummers P, Makar A, De Visschere P, Van Bockstal M, Van Dorpe J, De Neve W, Denys H, Vandecasteele K.

BMC Cancer. 2018 Nov 12;18(1):1101. doi: 10.1186/s12885-018-5007-0.


EXclusion of non-Involved uterus from the Target Volume (EXIT-trial): an individualized treatment for locally advanced cervical cancer using modern radiotherapy and imaging techniques.

Vandecasteele K, Tummers P, Van Bockstal M, De Visschere P, Vercauteren T, De Gersem W, Denys H, Naert E, Makar A, De Neve W.

BMC Cancer. 2018 Sep 17;18(1):898. doi: 10.1186/s12885-018-4800-0.


Collagen Alignment and Recurrence of DCIS-Letter.

Libbrecht L, Lambein K, Van Bockstal M, Denys H.

Cancer Epidemiol Biomarkers Prev. 2018 May;27(5):613. doi: 10.1158/1055-9965.EPI-17-1071. No abstract available.


Corneal Changes in Trastuzumab Emtansine Treatment.

Kreps EO, Derveaux T, Denys H.

Clin Breast Cancer. 2018 Aug;18(4):e427-e429. doi: 10.1016/j.clbc.2018.03.005. Epub 2018 Mar 12. No abstract available.


Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research.

Vergauwen G, Dhondt B, Van Deun J, De Smedt E, Berx G, Timmerman E, Gevaert K, Miinalainen I, Cocquyt V, Braems G, Van den Broecke R, Denys H, De Wever O, Hendrix A.

Sci Rep. 2017 Jun 2;7(1):2704. doi: 10.1038/s41598-017-02599-y.


Comparison of HER2 amplification status among breast cancer subgroups offers new insights in pathways of breast cancer progression.

Lambein K, Van Bockstal M, Vandemaele L, Van den Broecke R, Cocquyt V, Geenen S, Denys H, Libbrecht L.

Virchows Arch. 2017 Nov;471(5):575-587. doi: 10.1007/s00428-017-2161-8. Epub 2017 May 31.


Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth.

Lapeire L, Hendrix A, Lecoutere E, Van Bockstal M, Vandesompele J, Maynard D, Braems G, Van Den Broecke R, Müller C, Bracke M, Cocquyt V, Denys H, De Wever O.

Oncotarget. 2017 Jul 18;8(29):47239-47249. doi: 10.18632/oncotarget.17592.


The isolation of morphologically intact and biologically active extracellular vesicles from the secretome of cancer-associated adipose tissue.

Jeurissen S, Vergauwen G, Van Deun J, Lapeire L, Depoorter V, Miinalainen I, Sormunen R, Van den Broecke R, Braems G, Cocquyt V, Denys H, Hendrix A.

Cell Adh Migr. 2017 Mar 4;11(2):196-204. doi: 10.1080/19336918.2017.1279784. Epub 2017 Feb 1.


Incorporating PARP-inhibitors into clinical routine: A tailored treatment strategy to tackle ovarian cancer.

De Jaeghere E, Vandecasteele K, Claes K, Makar A, Tummers P, Cocquyt V, Denys H.

Acta Clin Belg. 2017 Feb;72(1):6-11. doi: 10.1080/17843286.2016.1188455. Epub 2016 May 31. Review.


When fat becomes an ally of the enemy: adipose tissue as collaborator in human breast cancer.

Lapeire L, Denys H, Cocquyt V, De Wever O.

Horm Mol Biol Clin Investig. 2015 Jul;23(1):21-38. doi: 10.1515/hmbci-2015-0018. Review.


Resection of single metachronous liver metastases from breast cancer stage I-II yield excellent overall and disease-free survival. Single center experience and review of the literature.

Vertriest C, Berardi G, Tomassini F, Vanden Broucke R, Depypere H, Cocquyt V, Denys H, Van Belle S, Troisi RI.

Dig Surg. 2015;32(1):52-9. doi: 10.1159/000375132. Epub 2015 Feb 11. Review.


Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion.

Van Bockstal M, Lambein K, Van Gele M, De Vlieghere E, Limame R, Braems G, Van den Broecke R, Cocquyt V, Denys H, Bracke M, Libbrecht L, De Wever O.

Oncoscience. 2014 Oct 15;1(10):634-48. eCollection 2014.


Cancer-associated adipose tissue promotes breast cancer progression by paracrine oncostatin M and Jak/STAT3 signaling.

Lapeire L, Hendrix A, Lambein K, Van Bockstal M, Braems G, Van Den Broecke R, Limame R, Mestdagh P, Vandesompele J, Vanhove C, Maynard D, Lehuédé C, Muller C, Valet P, Gespach CP, Bracke M, Cocquyt V, Denys H, De Wever O.

Cancer Res. 2014 Dec 1;74(23):6806-19. doi: 10.1158/0008-5472.CAN-14-0160. Epub 2014 Sep 24.


Histopathological characterization of ductal carcinoma in situ (DCIS) of the breast according to HER2 amplification status and molecular subtype.

Van Bockstal M, Lambein K, Denys H, Braems G, Nuyts A, Van den Broecke R, Cocquyt V, De Wever O, Libbrecht L.

Virchows Arch. 2014 Sep;465(3):275-89. doi: 10.1007/s00428-014-1609-3. Epub 2014 Jun 29.


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