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Items: 19


ABC Transporter-Mediated Multidrug-Resistant Cancer.

Amawi H, Sim HM, Tiwari AK, Ambudkar SV, Shukla S.

Adv Exp Med Biol. 2019;1141:549-580. doi: 10.1007/978-981-13-7647-4_12. Review.


The Effect of Long-Term Second-Generation Antipsychotics Use on the Metabolic Syndrome Parameters in Jordanian Population.

Abo Alrob O, Alazzam S, Alzoubi K, Nusair MB, Amawi H, Karasneh R, Rababa'h A, Nammas M.

Medicina (Kaunas). 2019 Jun 28;55(7). pii: E320. doi: 10.3390/medicina55070320.


Novel 3-((2-chloroquinolin-3-yl)methylene)indolin-2-one derivatives produce anticancer efficacy in ovarian cancer in vitro.

Karthikeyan C, Amawi H, Ashby CR Jr, Khare VM, Jones V, Hari Narayana Moorthy NS, Trivedi P, Tiwari AK.

Heliyon. 2019 May 14;5(5):e01603. doi: 10.1016/j.heliyon.2019.e01603. eCollection 2019 May.


Novel Thienopyrimidine Derivative, RP-010, Induces β-Catenin Fragmentation and Is Efficacious against Prostate Cancer Cells.

Amawi H, Hussein N, Boddu SHS, Karthikeyan C, Williams FE, Ashby CR Jr, Raman D, Trivedi P, Tiwari AK.

Cancers (Basel). 2019 May 23;11(5). pii: E711. doi: 10.3390/cancers11050711.


Cariprazine, A Dopamine D₂/D₃ Receptor Partial Agonist, Modulates ABCG2-Mediated Multidrug Resistance in Cancer.

Hussein N, Ashby CR Jr, Amawi H, Nyinawabera A, Vij A, Khare VM, Karthikeyan C, Tiwari AK.

Cancers (Basel). 2018 Sep 4;10(9). pii: E308. doi: 10.3390/cancers10090308.


Bax/Tubulin/Epithelial-Mesenchymal Pathways Determine the Efficacy of Silybin Analog HM015k in Colorectal Cancer Cell Growth and Metastasis.

Amawi H, Hussein NA, Ashby CR Jr, Alnafisah R, Sanglard LM, Manivannan E, Karthikeyan C, Trivedi P, Eisenmann KM, Robey RW, Tiwari AK.

Front Pharmacol. 2018 May 23;9:520. doi: 10.3389/fphar.2018.00520. eCollection 2018.


lH-Pyrazolo[3,4-b]quinolin-3-amine derivatives inhibit growth of colon cancer cells via apoptosis and sub G1 cell cycle arrest.

Karthikeyan C, Amawi H, Viana AG, Sanglard L, Hussein N, Saddler M, Ashby CR Jr, Moorthy NSHN, Trivedi P, Tiwari AK.

Bioorg Med Chem Lett. 2018 Jul 15;28(13):2244-2249. doi: 10.1016/j.bmcl.2018.05.045. Epub 2018 May 24.


Erratum to: Cancer chemoprevention through dietary flavonoids: what's limiting?

Amawi H, Ashby CR Jr, Tiwari AK.

Chin J Cancer. 2017 Aug 30;36(1):70. doi: 10.1186/s40880-017-0237-0. No abstract available.


Polyphenolic Nutrients in Cancer Chemoprevention and Metastasis: Role of the Epithelial-to-Mesenchymal (EMT) Pathway.

Amawi H, Ashby CR, Samuel T, Peraman R, Tiwari AK.

Nutrients. 2017 Aug 21;9(8). pii: E911. doi: 10.3390/nu9080911. Review.


HM015k, a Novel Silybin Derivative, Multi-Targets Metastatic Ovarian Cancer Cells and Is Safe in Zebrafish Toxicity Studies.

Amawi H, Hussein NA, Karthikeyan C, Manivannan E, Wisner A, Williams FE, Samuel T, Trivedi P, Ashby CR Jr, Tiwari AK.

Front Pharmacol. 2017 Aug 2;8:498. doi: 10.3389/fphar.2017.00498. eCollection 2017.


Thienopyrimidine derivatives exert their anticancer efficacy via apoptosis induction, oxidative stress and mitotic catastrophe.

Amawi H, Karthikeyan C, Pathak R, Hussein N, Christman R, Robey R, Ashby CR Jr, Trivedi P, Malhotra A, Tiwari AK.

Eur J Med Chem. 2017 Sep 29;138:1053-1065. doi: 10.1016/j.ejmech.2017.07.028. Epub 2017 Jul 20.


Cancer chemoprevention through dietary flavonoids: what's limiting?

Amawi H, Ashby CR Jr, Tiwari AK.

Chin J Cancer. 2017 Jun 19;36(1):50. doi: 10.1186/s40880-017-0217-4. Review. Erratum in: Chin J Cancer. 2017 Aug 30;36(1):70.


N-(1H-Pyrazol-3-yl)quinazolin-4-amines as a novel class of casein kinase 1δ/ε inhibitors: Synthesis, biological evaluation and molecular modeling studies.

Karthikeyan C, Jharia P, Waiker DK, Nusbaum AC, Amawi H, Kirwen EM, Christman R, Arudra SKC, Meijer L, Tiwari AK, Trivedi P.

Bioorg Med Chem Lett. 2017 Jun 15;27(12):2663-2667. doi: 10.1016/j.bmcl.2017.04.080. Epub 2017 Apr 27.


Design and discovery of silybin analogues as antiproliferative compounds using a ring disjunctive - Based, natural product lead optimization approach.

Manivannan E, Amawi H, Hussein N, Karthikeyan C, Fetcenko A, Narayana Moorthy NSH, Trivedi P, Tiwari AK.

Eur J Med Chem. 2017 Jun 16;133:365-378. doi: 10.1016/j.ejmech.2017.03.033. Epub 2017 Mar 22.


The dopamine D3 receptor antagonists PG01037, NGB2904, SB277011A, and U99194 reverse ABCG2 transporter-mediated drug resistance in cancer cell lines.

Hussein N, Amawi H, Karthikeyan C, Hall FS, Mittal R, Trivedi P, Ashby CR Jr, Tiwari AK.

Cancer Lett. 2017 Jun 28;396:167-180. doi: 10.1016/j.canlet.2017.03.015. Epub 2017 Mar 18.


2,3-Diaryl-3H-imidazo[4,5-b]pyridine derivatives as potential anticancer and anti-inflammatory agents.

Marie Kirwen E, Batra T, Karthikeyan C, Deora GS, Rathore V, Mulakayala C, Mulakayala N, Nusbaum AC, Chen J, Amawi H, McIntosh K, Sahabjada, Shivnath N, Chowarsia D, Sharma N, Arshad M, Trivedi P, Tiwari AK.

Acta Pharm Sin B. 2017 Jan;7(1):73-79. doi: 10.1016/j.apsb.2016.05.003. Epub 2016 Aug 6.


Pyrimido[1″,2″:1,5]pyrazolo[3,4-b]quinolines: Novel compounds that reverse ABCG2-mediated resistance in cancer cells.

Karthikeyan C, Malla R, Ashby CR Jr, Amawi H, Abbott KL, Moore J, Chen J, Balch C, Lee C, Flannery PC, Trivedi P, Faridi JS, Pondugula SR, Tiwari AK.

Cancer Lett. 2016 Jun 28;376(1):118-26. doi: 10.1016/j.canlet.2016.03.030. Epub 2016 Mar 21.


Synthesis, Antibacterial Evaluation and QSAR of α-Substituted-N₄-Acetamides of Ciprofloxacin and Norfloxacin.

Qandil AM, Al-Zoubi LO, Al-Bakri AG, Amawi HA, Al-Balas QA, Alkatheri AM, Albekairy AM.

Antibiotics (Basel). 2014 Jun 25;3(3):244-69. doi: 10.3390/antibiotics3030244.


Virtual lead identification of farnesyltransferase inhibitors based on ligand and structure-based pharmacophore techniques.

Al-Balas QA, Amawi HA, Hassan MA, Qandil AM, Almaaytah AM, Mhaidat NM.

Pharmaceuticals (Basel). 2013 May 27;6(6):700-15. doi: 10.3390/ph6060700.

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