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Items: 14


Combination Therapy of Chloroquine and C₂-Ceramide Enhances Cytotoxicity in Lung Cancer H460 and H1299 Cells.

Chou HL, Lin YH, Liu W, Wu CY, Li RN, Huang HW, Chou CH, Chiou SJ, Chiu CC.

Cancers (Basel). 2019 Mar 15;11(3). pii: E370. doi: 10.3390/cancers11030370.


Exogenous C₈-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells.

Chang YC, Fong Y, Tsai EM, Chang YG, Chou HL, Wu CY, Teng YN, Liu TC, Yuan SS, Chiu CC.

Int J Mol Sci. 2018 Oct 2;19(10). pii: E3010. doi: 10.3390/ijms19103010.


The Potential Role of Krüppel-Like Zinc-Finger Protein Glis3 in Genetic Diseases and Cancers.

Chou CK, Tang CJ, Chou HL, Liu CY, Ng MC, Chang YT, Yuan SF, Tsai EM, Chiu CC.

Arch Immunol Ther Exp (Warsz). 2017 Oct;65(5):381-389. doi: 10.1007/s00005-017-0470-x. Epub 2017 May 18. Review.


An XIST-related small RNA regulates KRAS G-quadruplex formation beyond X-inactivation.

Chang YC, Chiu CC, Yuo CY, Chan WL, Chang YS, Chang WH, Wu SM, Chou HL, Liu TC, Lu CY, Yang WK, Chang JG.

Oncotarget. 2016 Dec 27;7(52):86713-86729. doi: 10.18632/oncotarget.13433.


An Acetamide Derivative as a Camptothecin Sensitizer for Human Non-Small-Cell Lung Cancer Cells through Increased Oxidative Stress and JNK Activation.

Chou HL, Fong Y, Lin HH, Tsai EM, Chen JY, Chang WT, Wu CY, David Wang HM, Huang HW, Chiu CC.

Oxid Med Cell Longev. 2016;2016:9128102. Epub 2016 Oct 24.


A Quinone-Containing Compound Enhances Camptothecin-Induced Apoptosis of Lung Cancer Through Modulating Endogenous ROS and ERK Signaling.

Chou HL, Fong Y, Wei CK, Tsai EM, Chen JY, Chang WT, Wu CY, Huang HW, Chiu CC.

Arch Immunol Ther Exp (Warsz). 2017 Jun;65(3):241-252. doi: 10.1007/s00005-016-0424-8. Epub 2016 Sep 27.


9-bis[2-(pyrrolidin-1-yl)ethoxy]-6-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-11H-indeno[1, 2-c]quinolin-11-one (BPIQ), A Quinoline Derivative Inhibits Human Hepatocellular Carcinoma Cells by Inducing ER Stress and Apoptosis.

Chang WT, Fong Y, Chuang SC, Chou CK, Chou HL, Yang CF, Tseng CH, Chen YL, Chiu CC.

Anticancer Agents Med Chem. 2017;17(5):692-700. doi: 10.2174/1871520616666160802121456.


BPIQ, a novel synthetic quinoline derivative, inhibits growth and induces mitochondrial apoptosis of lung cancer cells in vitro and in zebrafish xenograft model.

Chiu CC, Chou HL, Chen BH, Chang KF, Tseng CH, Fong Y, Fu TF, Chang HW, Wu CY, Tsai EM, Lin SR, Chen YL.

BMC Cancer. 2015 Dec 16;15:962. doi: 10.1186/s12885-015-1970-x.


Chondroitin sulfate-polyethylenimine copolymer-coated superparamagnetic iron oxide nanoparticles as an efficient magneto-gene carrier for microRNA-encoding plasmid DNA delivery.

Lo YL, Chou HL, Liao ZX, Huang SJ, Ke JH, Liu YS, Chiu CC, Wang LF.

Nanoscale. 2015 May 14;7(18):8554-65. doi: 10.1039/c5nr01404b.


The antiproliferative and apoptotic effects of sirtinol, a sirtuin inhibitor on human lung cancer cells by modulating Akt/β-catenin-Foxo3a axis.

Fong Y, Lin YC, Wu CY, Wang HM, Lin LL, Chou HL, Teng YN, Yuan SS, Chiu CC.

ScientificWorldJournal. 2014;2014:937051. doi: 10.1155/2014/937051. Epub 2014 Aug 12.


The antiproliferative effect of C2-ceramide on lung cancer cells through apoptosis by inhibiting Akt and NFκB.

Lin IL, Chou HL, Lee JC, Chen FW, Fong Y, Chang WC, Huang HW, Wu CY, Chang WT, Wang HD, Chiu CC.

Cancer Cell Int. 2014 Jan 6;14(1):1. doi: 10.1186/1475-2867-14-1.


Cardiotoxin III inhibits proliferation and migration of oral cancer cells through MAPK and MMP signaling.

Yen CY, Liang SS, Han LY, Chou HL, Chou CK, Lin SR, Chiu CC.

ScientificWorldJournal. 2013 Apr 8;2013:650946. doi: 10.1155/2013/650946. Print 2013.


Protective effect of caffeic acid on paclitaxel induced anti-proliferation and apoptosis of lung cancer cells involves NF-κB pathway.

Lin CL, Chen RF, Chen JY, Chu YC, Wang HM, Chou HL, Chang WC, Fong Y, Chang WT, Wu CY, Chiu CC.

Int J Mol Sci. 2012;13(5):6236-45. doi: 10.3390/ijms13056236. Epub 2012 May 21.


Bio-functional constituents from the stems of Liriodendron tulipifera.

Chiu CC, Chou HL, Wu PF, Chen HL, Wang HM, Chen CY.

Molecules. 2012 Apr 10;17(4):4357-72. doi: 10.3390/molecules17044357.

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