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Items: 1 to 20 of 39

1.

STAT3 Inhibits CD103+ cDC1 Vaccine Efficacy in Murine Breast Cancer.

Chrisikos TT, Zhou Y, Li HS, Babcock RL, Wan X, Patel B, Newton K, Mancuso JJ, Watowich SS.

Cancers (Basel). 2020 Jan 4;12(1). pii: E128. doi: 10.3390/cancers12010128.

2.

Preventing abnormal NF-κB activation and autoimmunity by Otub1-mediated p100 stabilization.

Li Y, Yang JY, Xie X, Jie Z, Zhang L, Shi J, Lin D, Gu M, Zhou X, Li HS, Watowich SS, Jain A, Yun Jung S, Qin J, Cheng X, Sun SC.

Cell Res. 2019 Jun;29(6):474-485. doi: 10.1038/s41422-019-0174-3. Epub 2019 May 13.

PMID:
31086255
3.

CXCR5+CD8+ T cells are a distinct functional subset with an antitumor activity.

Chu F, Li HS, Liu X, Cao J, Ma W, Ma Y, Weng J, Zhu Z, Cheng X, Wang Z, Liu J, Jiang ZY, Luong AU, Peng W, Wang J, Balakrishnan K, Yee C, Dong C, Davis RE, Watowich SS, Neelapu SS.

Leukemia. 2019 Nov;33(11):2640-2653. doi: 10.1038/s41375-019-0464-2. Epub 2019 Apr 25.

4.

PPARD and Interferon Gamma Promote Transformation of Gastric Progenitor Cells and Tumorigenesis in Mice.

Zuo X, Deguchi Y, Xu W, Liu Y, Li HS, Wei D, Tian R, Chen W, Xu M, Yang Y, Gao S, Jaoude JC, Liu F, Chrieki SP, Moussalli MJ, Gagea M, Sebastian MM, Zheng X, Tan D, Broaddus R, Wang J, Ajami NJ, Swennes AG, Watowich SS, Shureiqi I.

Gastroenterology. 2019 Jul;157(1):163-178. doi: 10.1053/j.gastro.2019.03.018. Epub 2019 Mar 15.

PMID:
30885780
5.

Molecular regulation of dendritic cell development and function in homeostasis, inflammation, and cancer.

Chrisikos TT, Zhou Y, Slone N, Babcock R, Watowich SS, Li HS.

Mol Immunol. 2019 Jun;110:24-39. doi: 10.1016/j.molimm.2018.01.014. Epub 2018 Mar 15. Review.

PMID:
29549977
6.

Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis.

Zhang H, Li HS, Hillmer EJ, Zhao Y, Chrisikos TT, Hu H, Wu X, Thompson EJ, Clise-Dwyer K, Millerchip KA, Wei Y, Puebla-Osorio N, Kaushik S, Santos MA, Wang B, Garcia-Manero G, Wang J, Sun SC, Watowich SS.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2311-E2319. doi: 10.1073/pnas.1713889115. Epub 2018 Feb 20.

7.

MicroRNA-22 controls interferon alpha production and erythroid maturation in response to infectious stress in mice.

Kadmon CS, Landers CT, Li HS, Watowich SS, Rodriguez A, King KY.

Exp Hematol. 2017 Dec;56:7-15. doi: 10.1016/j.exphem.2017.09.001. Epub 2017 Sep 11.

8.

Mesenchymal stem cells and their therapeutic applications in inflammatory bowel disease.

Mao F, Tu Q, Wang L, Chu F, Li X, Li HS, Xu W.

Oncotarget. 2017 Jun 6;8(23):38008-38021. doi: 10.18632/oncotarget.16682. Review.

9.

The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity.

Xiao Y, Zou Q, Xie X, Liu T, Li HS, Jie Z, Jin J, Hu H, Manyam G, Zhang L, Cheng X, Wang H, Marie I, Levy DE, Watowich SS, Sun SC.

J Exp Med. 2017 May 1;214(5):1493-1507. doi: 10.1084/jem.20161524. Epub 2017 Mar 29.

10.

Bypassing STAT3-mediated inhibition of the transcriptional regulator ID2 improves the antitumor efficacy of dendritic cells.

Li HS, Liu C, Xiao Y, Chu F, Liang X, Peng W, Hu J, Neelapu SS, Sun SC, Hwu P, Watowich SS.

Sci Signal. 2016 Sep 27;9(447):ra94. doi: 10.1126/scisignal.aaf3957.

11.

STAT3 signaling in immunity.

Hillmer EJ, Zhang H, Li HS, Watowich SS.

Cytokine Growth Factor Rev. 2016 Oct;31:1-15. doi: 10.1016/j.cytogfr.2016.05.001. Epub 2016 May 9. Review.

12.

Loss of c-Kit and bone marrow failure upon conditional removal of the GATA-2 C-terminal zinc finger domain in adult mice.

Li HS, Jin J, Liang X, Matatall KA, Ma Y, Zhang H, Ullrich SE, King KY, Sun SC, Watowich SS.

Eur J Haematol. 2016 Sep;97(3):261-70. doi: 10.1111/ejh.12719. Epub 2016 Jan 14.

13.

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.

Peng W, Chen JQ, Liu C, Malu S, Creasy C, Tetzlaff MT, Xu C, McKenzie JA, Zhang C, Liang X, Williams LJ, Deng W, Chen G, Mbofung R, Lazar AJ, Torres-Cabala CA, Cooper ZA, Chen PL, Tieu TN, Spranger S, Yu X, Bernatchez C, Forget MA, Haymaker C, Amaria R, McQuade JL, Glitza IC, Cascone T, Li HS, Kwong LN, Heffernan TP, Hu J, Bassett RL Jr, Bosenberg MW, Woodman SE, Overwijk WW, Lizée G, Roszik J, Gajewski TF, Wargo JA, Gershenwald JE, Radvanyi L, Davies MA, Hwu P.

Cancer Discov. 2016 Feb;6(2):202-16. doi: 10.1158/2159-8290.CD-15-0283. Epub 2015 Dec 8.

14.

15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway.

Mao F, Xu M, Zuo X, Yu J, Xu W, Moussalli MJ, Elias E, Li HS, Watowich SS, Shureiqi I.

FASEB J. 2015 Jun;29(6):2359-70. doi: 10.1096/fj.14-264515. Epub 2015 Feb 24.

15.

STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13.

Zhang H, Hu H, Greeley N, Jin J, Matthews AJ, Ohashi E, Caetano MS, Li HS, Wu X, Mandal PK, McMurray JS, Moghaddam SJ, Sun SC, Watowich SS.

Nat Commun. 2014 Dec 15;5:5798. doi: 10.1038/ncomms6798.

16.

Innate immune regulation by STAT-mediated transcriptional mechanisms.

Li HS, Watowich SS.

Immunol Rev. 2014 Sep;261(1):84-101. doi: 10.1111/imr.12198. Review.

17.

USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses.

Zou Q, Jin J, Hu H, Li HS, Romano S, Xiao Y, Nakaya M, Zhou X, Cheng X, Yang P, Lozano G, Zhu C, Watowich SS, Ullrich SE, Sun SC.

Nat Immunol. 2014 Jun;15(6):562-70. doi: 10.1038/ni.2885. Epub 2014 Apr 28.

19.

Noncanonical NF-κB pathway controls the production of type I interferons in antiviral innate immunity.

Jin J, Hu H, Li HS, Yu J, Xiao Y, Brittain GC, Zou Q, Cheng X, Mallette FA, Watowich SS, Sun SC.

Immunity. 2014 Mar 20;40(3):342-54. doi: 10.1016/j.immuni.2014.02.006.

20.

Diversification of dendritic cell subsets: Emerging roles for STAT proteins.

Li HS, Watowich SS.

JAKSTAT. 2013 Oct 1;2(4):e25112. doi: 10.4161/jkst.25112. Epub 2013 May 21. Review.

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