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Items: 1 to 20 of 54

1.

The mechanism of cancer drug addiction in ALK-positive T-Cell lymphoma.

Rajan SS, Amin AD, Li L, Rolland DC, Li H, Kwon D, Kweh MF, Arumov A, Roberts ER, Yan A, Basrur V, Elenitoba-Johnson KSJ, Chen XS, Puvvada SD, Lussier YA, Bilbao D, Lim MS, Schatz JH.

Oncogene. 2019 Dec 5. doi: 10.1038/s41388-019-1136-4. [Epub ahead of print]

PMID:
31804622
2.

NIR-Activated Polymeric Nanoplatform with Upper Critical Solution Temperature for Image-Guided Synergistic Photothermal Therapy and Chemotherapy.

Tian J, Huang B, Li H, Cao H, Zhang W.

Biomacromolecules. 2019 Jun 10;20(6):2338-2349. doi: 10.1021/acs.biomac.9b00321. Epub 2019 May 6.

PMID:
31017765
3.

Precision drug repurposing via convergent eQTL-based molecules and pathway targeting independent disease-associated polymorphisms.

Vitali F, Berghout J, Fan J, Li J, Li Q, Li H, Lussier YA.

Pac Symp Biocomput. 2019;24:308-319.

4.

Novel disease syndromes unveiled by integrative multiscale network analysis of diseases sharing molecular effectors and comorbidities.

Li H, Fan J, Vitali F, Berghout J, Aberasturi D, Li J, Wilson L, Chiu W, Pumarejo M, Han J, Kenost C, Koripella PC, Pouladi N, Billheimer D, Bedrick EJ, Lussier YA.

BMC Med Genomics. 2018 Dec 31;11(Suppl 6):112. doi: 10.1186/s12920-018-0428-9.

5.

Multicenter study of diagnostic procedures, genetic aberration analysis, and first-line treatment of lung cancer in Jiangsu Province, China.

Hu Y, Hu H, Miao L, Zhao X, Gu W, Heng W, Meng Z, Feng J, You Y, Xu X, Hu R, Li H, Zhao J, Zhu X, Shi M, Shen L, Zhang X, Yin X, Ma H, Shi M, Yu Y, Lv H, Cai L, Feng G, Zhang Y, Wu F, Lv T, Song Y.

Thorac Cancer. 2018 Mar;9(3):376-383. doi: 10.1111/1759-7714.12588. Epub 2018 Jan 17.

6.
7.

A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations.

Gardeux V, Berghout J, Achour I, Schissler AG, Li Q, Kenost C, Li J, Shang Y, Bosco A, Saner D, Halonen MJ, Jackson DJ, Li H, Martinez FD, Lussier YA.

J Am Med Inform Assoc. 2017 Nov 1;24(6):1116-1126. doi: 10.1093/jamia/ocx069.

8.

N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes.

Li Q, Schissler AG, Gardeux V, Achour I, Kenost C, Berghout J, Li H, Zhang HH, Lussier YA.

BMC Med Genomics. 2017 May 24;10(Suppl 1):27. doi: 10.1186/s12920-017-0263-4.

9.

kMEn: Analyzing noisy and bidirectional transcriptional pathway responses in single subjects.

Li Q, Schissler AG, Gardeux V, Berghout J, Achour I, Kenost C, Li H, Zhang HH, Lussier YA.

J Biomed Inform. 2017 Feb;66:32-41. doi: 10.1016/j.jbi.2016.12.009. Epub 2016 Dec 19.

10.

Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions.

Li H, Achour I, Bastarache L, Berghout J, Gardeux V, Li J, Lee Y, Pesce L, Yang X, Ramos KS, Foster I, Denny JC, Moore JH, Lussier YA.

NPJ Genom Med. 2016;1. pii: 16006. Epub 2016 Apr 27.

11.

Analysis of aggregated cell-cell statistical distances within pathways unveils therapeutic-resistance mechanisms in circulating tumor cells.

Schissler AG, Li Q, Chen JL, Kenost C, Achour I, Billheimer DD, Li H, Piegorsch WW, Lussier YA.

Bioinformatics. 2016 Jun 15;32(12):i80-i89. doi: 10.1093/bioinformatics/btw248.

12.

[The significance of multi-criteria decision analysis for the bundle treatment of severe pneumonia].

Xu J, Zhao J, Jia X, Wang H, Wang G, Li H.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2015 Oct;27(10):796-9. Chinese.

13.

eQTL networks unveil enriched mRNA master integrators downstream of complex disease-associated SNPs.

Li H, Pouladi N, Achour I, Gardeux V, Li J, Li Q, Zhang HH, Martinez FD, 'Skip' Garcia JGN, Lussier YA.

J Biomed Inform. 2015 Dec;58:226-234. doi: 10.1016/j.jbi.2015.10.010. Epub 2015 Oct 30.

14.

Dynamic changes of RNA-sequencing expression for precision medicine: N-of-1-pathways Mahalanobis distance within pathways of single subjects predicts breast cancer survival.

Schissler AG, Gardeux V, Li Q, Achour I, Li H, Piegorsch WW, Lussier YA.

Bioinformatics. 2015 Jun 15;31(12):i293-302. doi: 10.1093/bioinformatics/btv253.

15.

Prognostic implication of pulmonary function at the beginning of postoperative radiotherapy in non-small cell lung cancer.

Kim H, Lussier YA, Noh OK, Li H, Oh YT, Heo J.

Radiother Oncol. 2014 Dec;113(3):374-8. doi: 10.1016/j.radonc.2014.11.007. Epub 2014 Nov 28.

16.
17.

'N-of-1-pathways' unveils personal deregulated mechanisms from a single pair of RNA-Seq samples: towards precision medicine.

Gardeux V, Achour I, Li J, Maienschein-Cline M, Li H, Pesce L, Parinandi G, Bahroos N, Winn R, Foster I, Garcia JG, Lussier YA.

J Am Med Inform Assoc. 2014 Nov-Dec;21(6):1015-25. doi: 10.1136/amiajnl-2013-002519. Epub 2014 Jun 12.

18.

In Silico cancer cell versus stroma cellularity index computed from species-specific human and mouse transcriptome of xenograft models: towards accurate stroma targeting therapy assessment.

Yang X, Huang Y, Lee Y, Gardeux V, Achour I, Regan K, Rebman E, Li H, Lussier YA.

BMC Med Genomics. 2014;7 Suppl 1:S2. doi: 10.1186/1755-8794-7-S1-S2. Epub 2014 May 8.

19.

The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis.

Huang LS, Mathew B, Li H, Zhao Y, Ma SF, Noth I, Reddy SP, Harijith A, Usatyuk PV, Berdyshev EV, Kaminski N, Zhou T, Zhang W, Zhang Y, Rehman J, Kotha SR, Gurney TO, Parinandi NL, Lussier YA, Garcia JG, Natarajan V.

Am J Respir Crit Care Med. 2014 Jun 1;189(11):1402-15. doi: 10.1164/rccm.201310-1917OC.

20.

COPD Hospitalization Risk Increased with Distinct Patterns of Multiple Systems Comorbidities Unveiled by Network Modeling.

Lee YJ, Boyd AD, Li JJ, Gardeux V, Kenost C, Saner D, Li H, Abraham I, Krishnan JA, Lussier YA.

AMIA Annu Symp Proc. 2014 Nov 14;2014:855-64. eCollection 2014.

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