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Items: 1 to 20 of 27

1.

Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence.

Do H, Makthal N, Chandrangsu P, Olsen RJ, Helmann JD, Musser JM, Kumaraswami M.

Nucleic Acids Res. 2019 Sep 5;47(15):8333-8334. doi: 10.1093/nar/gkz641. No abstract available.

2.

Environmental pH and peptide signaling control virulence of Streptococcus pyogenes via a quorum-sensing pathway.

Do H, Makthal N, VanderWal AR, Saavedra MO, Olsen RJ, Musser JM, Kumaraswami M.

Nat Commun. 2019 Jun 13;10(1):2586. doi: 10.1038/s41467-019-10556-8.

3.

Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence.

Do H, Makthal N, Chandrangsu P, Olsen RJ, Helmann JD, Musser JM, Kumaraswami M.

Nucleic Acids Res. 2019 Aug 22;47(14):7476-7493. doi: 10.1093/nar/gkz524.

4.

Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis.

Kachroo P, Eraso JM, Beres SB, Olsen RJ, Zhu L, Nasser W, Bernard PE, Cantu CC, Saavedra MO, Arredondo MJ, Strope B, Do H, Kumaraswami M, Vuopio J, Gröndahl-Yli-Hannuksela K, Kristinsson KG, Gottfredsson M, Pesonen M, Pensar J, Davenport ER, Clark AG, Corander J, Caugant DA, Gaini S, Magnussen MD, Kubiak SL, Nguyen HAT, Long SW, Porter AR, DeLeo FR, Musser JM.

Nat Genet. 2019 Mar;51(3):548-559. doi: 10.1038/s41588-018-0343-1. Epub 2019 Feb 18.

PMID:
30778225
5.

Signaling by a Conserved Quorum Sensing Pathway Contributes to Growth Ex Vivo and Oropharyngeal Colonization of Human Pathogen Group A Streptococcus.

Makthal N, Do H, VanderWal AR, Olsen RJ, Musser JM, Kumaraswami M.

Infect Immun. 2018 Apr 23;86(5). pii: e00169-18. doi: 10.1128/IAI.00169-18. Print 2018 May.

6.
7.

Leaderless secreted peptide signaling molecule alters global gene expression and increases virulence of a human bacterial pathogen.

Do H, Makthal N, VanderWal AR, Rettel M, Savitski MM, Peschek N, Papenfort K, Olsen RJ, Musser JM, Kumaraswami M.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8498-E8507. doi: 10.1073/pnas.1705972114. Epub 2017 Sep 18.

8.

A Critical Role of Zinc Importer AdcABC in Group A Streptococcus-Host Interactions During Infection and Its Implications for Vaccine Development.

Makthal N, Nguyen K, Do H, Gavagan M, Chandrangsu P, Helmann JD, Olsen RJ, Kumaraswami M.

EBioMedicine. 2017 Jul;21:131-141. doi: 10.1016/j.ebiom.2017.05.030. Epub 2017 Jun 2.

9.

Structure and catalytic mechanism of monodehydroascorbate reductase, MDHAR, from Oryza sativa L. japonica.

Park AK, Kim IS, Do H, Jeon BW, Lee CW, Roh SJ, Shin SC, Park H, Kim YS, Kim YH, Yoon HS, Lee JH, Kim HW.

Sci Rep. 2016 Sep 22;6:33903. doi: 10.1038/srep33903.

10.

Structural Mechanisms of Peptide Recognition and Allosteric Modulation of Gene Regulation by the RRNPP Family of Quorum-Sensing Regulators.

Do H, Kumaraswami M.

J Mol Biol. 2016 Jul 17;428(14):2793-804. doi: 10.1016/j.jmb.2016.05.026. Epub 2016 Jun 7. Review.

11.

Crystal structure and modeling of the tetrahedral intermediate state of methylmalonate-semialdehyde dehydrogenase (MMSDH) from Oceanimonas doudoroffii.

Do H, Lee CW, Lee SG, Kang H, Park CM, Kim HJ, Park H, Park H, Lee JH.

J Microbiol. 2016 Feb;54(2):114-21. doi: 10.1007/s12275-016-5549-2. Epub 2016 Feb 2.

PMID:
26832667
12.

Structural understanding of the recycling of oxidized ascorbate by dehydroascorbate reductase (OsDHAR) from Oryza sativa L. japonica.

Do H, Kim IS, Jeon BW, Lee CW, Park AK, Wi AR, Shin SC, Park H, Kim YS, Yoon HS, Kim HW, Lee JH.

Sci Rep. 2016 Jan 18;6:19498. doi: 10.1038/srep19498.

13.

Structural and functional analysis of RopB: a major virulence regulator in Streptococcus pyogenes.

Makthal N, Gavagan M, Do H, Olsen RJ, Musser JM, Kumaraswami M.

Mol Microbiol. 2016 Mar;99(6):1119-33. doi: 10.1111/mmi.13294. Epub 2016 Feb 19.

14.

Crystal Structure and Comparative Sequence Analysis of GmhA from Colwellia psychrerythraea Strain 34H Provides Insight into Functional Similarity with DiaA.

Do H, Yun JS, Lee CW, Choi YJ, Kim HY, Kim YJ, Park H, Chang JH, Lee JH.

Mol Cells. 2015 Dec;38(12):1086-95. doi: 10.14348/molcells.2015.0191. Epub 2015 Nov 26.

15.

Structural basis for the ligand-binding specificity of fatty acid-binding proteins (pFABP4 and pFABP5) in gentoo penguin.

Lee CW, Kim JE, Do H, Kim RO, Lee SG, Park HH, Chang JH, Yim JH, Park H, Kim IC, Lee JH.

Biochem Biophys Res Commun. 2015 Sep 11;465(1):12-8. doi: 10.1016/j.bbrc.2015.07.087. Epub 2015 Jul 20.

PMID:
26206084
16.

Crystal structure of UbiX, an aromatic acid decarboxylase from the psychrophilic bacterium Colwellia psychrerythraea that undergoes FMN-induced conformational changes.

Do H, Kim SJ, Lee CW, Kim HW, Park HH, Kim HM, Park H, Park H, Lee JH.

Sci Rep. 2015 Feb 3;5:8196. doi: 10.1038/srep08196.

17.

Purification, characterization and preliminary X-ray crystallographic studies of monodehydroascorbate reductase from Oryza sativa L. japonica.

Do H, Kim IS, Kim YS, Shin SY, Kim JJ, Mok JE, Park SI, Wi AR, Park H, Lee JH, Yoon HS, Kim HW.

Acta Crystallogr F Struct Biol Commun. 2014 Sep;70(Pt 9):1244-8. doi: 10.1107/S2053230X14015908. Epub 2014 Aug 27.

18.

Crystallization and preliminary X-ray crystallographic studies of dehydroascorbate reductase (DHAR) from Oryza sativa L. japonica.

Do H, Kim IS, Kim YS, Shin SY, Kim JJ, Mok JE, Park SI, Wi AR, Park H, Kim HW, Yoon HS, Lee JH.

Acta Crystallogr F Struct Biol Commun. 2014 Jun;70(Pt 6):781-5. doi: 10.1107/S2053230X14009133. Epub 2014 May 24.

19.

Structure-based characterization and antifreeze properties of a hyperactive ice-binding protein from the Antarctic bacterium Flavobacterium frigoris PS1.

Do H, Kim SJ, Kim HJ, Lee JH.

Acta Crystallogr D Biol Crystallogr. 2014 Apr;70(Pt 4):1061-73. doi: 10.1107/S1399004714000996. Epub 2014 Mar 19.

PMID:
24699650
20.

Purification, crystallization and preliminary X-ray crystallographic studies of FMN-bound and FMN-free forms of aromatic acid decarboxylase (CpsUbiX) from the psychrophilic bacterium Colwellia psychrerythraea 34H.

Do H, Lee CW, Han SJ, Lee SG, Kim HJ, Park H, Lee JH.

Acta Crystallogr F Struct Biol Commun. 2014 Feb;70(Pt 2):215-20. doi: 10.1107/S2053230X1303447X. Epub 2014 Jan 21.

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