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Items: 10

1.

Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases.

Holmgren G, Ulfenborg B, Asplund A, Toet K, Andersson CX, Hammarstedt A, Hanemaaijer R, Küppers-Munther B, Synnergren J.

Int J Mol Sci. 2020 Jan 11;21(2). pii: E469. doi: 10.3390/ijms21020469.

2.

Artificial neural networks improve and simplify intensive care mortality prognostication: a national cohort study of 217,289 first-time intensive care unit admissions.

Holmgren G, Andersson P, Jakobsson A, Frigyesi A.

J Intensive Care. 2019 Aug 16;7:44. doi: 10.1186/s40560-019-0393-1. eCollection 2019.

3.

Expression Profiling of Human Pluripotent Stem Cell-Derived Cardiomyocytes Exposed to Doxorubicin-Integration and Visualization of Multi-Omics Data.

Holmgren G, Sartipy P, Andersson CX, Lindahl A, Synnergren J.

Toxicol Sci. 2018 May 1;163(1):182-195. doi: 10.1093/toxsci/kfy012.

PMID:
29385562
4.

MicroRNAs as potential biomarkers for doxorubicin-induced cardiotoxicity.

Holmgren G, Synnergren J, Andersson CX, Lindahl A, Sartipy P.

Toxicol In Vitro. 2016 Aug;34:26-34. doi: 10.1016/j.tiv.2016.03.009. Epub 2016 Apr 6.

PMID:
27033315
5.

High Content Analysis of Human Pluripotent Stem Cell Derived Hepatocytes Reveals Drug Induced Steatosis and Phospholipidosis.

Pradip A, Steel D, Jacobsson S, Holmgren G, Ingelman-Sundberg M, Sartipy P, Björquist P, Johansson I, Edsbagge J.

Stem Cells Int. 2016;2016:2475631. doi: 10.1155/2016/2475631. Epub 2016 Jan 5.

6.

Identification of stable reference genes in differentiating human pluripotent stem cells.

Holmgren G, Ghosheh N, Zeng X, Bogestål Y, Sartipy P, Synnergren J.

Physiol Genomics. 2015 Jun;47(6):232-9. doi: 10.1152/physiolgenomics.00130.2014. Epub 2015 Apr 7.

PMID:
25852171
7.

Identification of novel biomarkers for doxorubicin-induced toxicity in human cardiomyocytes derived from pluripotent stem cells.

Holmgren G, Synnergren J, Bogestål Y, Améen C, Åkesson K, Holmgren S, Lindahl A, Sartipy P.

Toxicology. 2015 Feb 3;328:102-11. doi: 10.1016/j.tox.2014.12.018. Epub 2014 Dec 18.

8.

Long-term chronic toxicity testing using human pluripotent stem cell-derived hepatocytes.

Holmgren G, Sjögren AK, Barragan I, Sabirsh A, Sartipy P, Synnergren J, Björquist P, Ingelman-Sundberg M, Andersson TB, Edsbagge J.

Drug Metab Dispos. 2014 Sep;42(9):1401-6. doi: 10.1124/dmd.114.059154. Epub 2014 Jun 30.

PMID:
24980256
9.

Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells.

Ulvestad M, Nordell P, Asplund A, Rehnström M, Jacobsson S, Holmgren G, Davidson L, Brolén G, Edsbagge J, Björquist P, Küppers-Munther B, Andersson TB.

Biochem Pharmacol. 2013 Sep 1;86(5):691-702. doi: 10.1016/j.bcp.2013.06.029. Epub 2013 Jul 12.

PMID:
23856292
10.

Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models.

Doktorova TY, Yildirimman R, Vinken M, Vilardell M, Vanhaecke T, Gmuender H, Bort R, Brolen G, Holmgren G, Li R, Chesne C, van Delft J, Kleinjans J, Castell J, Bjorquist P, Herwig R, Rogiers V.

Carcinogenesis. 2013 Jun;34(6):1393-402. doi: 10.1093/carcin/bgt054. Epub 2013 Feb 7.

PMID:
23393228

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