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Genes (Basel). 2019 Nov 14;10(11). pii: E925. doi: 10.3390/genes10110925.

Tomato Natural Resistance Genes in Controlling the Root-Knot Nematode.

El-Sappah AH1,2,3, M M I1,2, H El-Awady H1,2, Yan S1,2, Qi S1,2, Liu J1,2, Cheng GT1,2, Liang Y1,2.

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College of Horticulture, Northwest A&F University, Yangling 712100, China.
State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling 712100, China.
Genetics Department, Faculty of Agriculture, Zagazig University, 44511 Zagazig, Egypt.


The root-knot nematode (RKN) is one of the most dangerous and widespread types of nematodes affecting tomatoes. There are few methods for controlling nematodes in tomatoes. Nature resistance genes (R-genes) are important in conferring resistance against nematodes. These genes that confer resistance to the RKN have already been identified as Mi-1, Mi-2, Mi-3, Mi-4, Mi-5, Mi-6, Mi-7, Mi-8, Mi-9, and Mi-HT. Only five of these genes have been mapped. The major problem is that their resistance breaks down at high temperatures. Some of these genes still work at high temperatures. In this paper, the mechanism and characteristics of these natural resistance genes are summarized. Other difficulties in using these genes in the resistance and how to improve them are also mentioned.


Mi resistance genes; gene-based marker; heat-stable resistance; root-knot nematode; tomato-resistant resources

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