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Molecules. 2019 May 17;24(10). pii: E1913. doi: 10.3390/molecules24101913.

Lamium Plants-A Comprehensive Review on Health Benefits and Biological Activities.

Author information

1
Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam 44340847, Iran. bahar.salehi007@gmail.com.
2
Department of Pharmaceutical Sciences, State University of Ponta Grossa, Ponta Grossa, Paraná 84030900, Brasil. lorenearmstrong@hotmail.com.
3
Department of Biomedical Sciences, University of Cagliari, s.s. 554 bivio Sestu, I-09042 Monserrato, CA, Italy. rescigno@unica.it.
4
Faculty of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty 480012, Kazakhstan. balakyz@mail.ru.
5
Faculty of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty 480012, Kazakhstan. sitigulnaz@mail.ru.
6
Department of Medicinal and Aromatic Plants, University of Health Sciences, 34668 Istanbul, Turkey. ahmet.beyatli@sbu.edu.tr.
7
Department of Health Sciences; Faculty of Science, University of Mauritius, Réduit 80837, Mauritius. sharmeenjugs@gmail.com.
8
Department of Health Sciences; Faculty of Science, University of Mauritius, Réduit 80837, Mauritius. f.mahomoodally@uom.ac.mu.
9
Department of Pharmaceutical Technology, Avicenna Tajik State Medical University, Rudaki 139, Dushanbe 734003, Tajikistan. shfarukh@mail.ru.
10
CREA-Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy. alessandra.durazzo@crea.gov.it.
11
CREA-Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy. massimo.lucarini@crea.gov.it.
12
Department of Pharmacy, University of Napoli Federico II, Via D. Montesano, 49-80131 Napoli, Italy. asantini@unina.it.
13
Department of Health Sciences, University Magna Graecia, viale Europa-Germaneto, 88100 Catanzaro, Italy. l.abenavoli@unicz.it.
14
Department of Agricultural Sciences, University of Naples Federico II, 80055 Portici, Italy. rafcapas@unina.it.
15
Zabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol 61615-585, Iran. javad.sharifirad@gmail.com.

Abstract

This work is an updated snapshot of Lamium plants and their biological activities. The main features of the plant are described and the components of its essential oils are summarized. The traditional medicinal uses of Lamium plants has been reported. The presence of these chemicals i.e., hydroxycinnamic acids, iridoids, secoiridoids, flavonoids, anthocyanins, phenylpropanoids, phytoecdysteroids, benzoxazinoids, betaine can provide biological activities. After the discussion of antioxidant properties documented for Lamium plants, the biological activities, studied using in vitro models, antimicrobial, antiviral, anti-inflammatory, anti-nociceptive activity, and pain therapy and cytotoxicity and cytoprotective activity are here described and discussed. Finally, targeted examples of in vivo studies are reported.

KEYWORDS:

Lamium plants; anti-inflammatory; antioxidant; antiviral; cytotoxicity

PMID:
31109023
DOI:
10.3390/molecules24101913
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